Faculty profile

Associate Professor (Part-Time)MedicineMcMaster University

Research

Research areas, by share of publications

Research areas are derived from OpenAlex topics of their publications.

From the 150 most recent of 201 publications.

01

Modulating pro-fibrotic macrophages using yeast beta-glucan microparticles prepared by Pressurized Gas eXpanded liquid (PGX) Technology®

Naiel S, Dowdall N, Zhou Q, Ali P, Hayat A, Vierhout M, Wong EY, Couto R, Yépez B, Seifried B

Biomaterials20256 citations
02

Upregulation of HSP90α in the lungs and circulation in sarcoidosis

Isshiki T, Sunakawa M, Vierhout M, Ayoub A, Ali P, Naiel S, Miyoshi S, Naqvi A, Hambly N, Kishi K

Frontiers in Medicine20253 citations
03

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Dowdall N, Naiel S, Zhou Q, Ali P, Yousof TR, Wong E, Couto R, Yépez B, Seifried B, Moquin P

Advanced healthcare materials20252 citations
04

Late Breaking Abstract - Proteomic profiling of bronchoalveolar lavage identifies soluble biomarkers of poor prognosis in IPF and CTD-ILD patients

Ruwisch J, Seeliger B, Zhao F, Barron A, Loureiro J, Mccauley K, Ask K, Prasse A

2025
05

Therapeutic strategies to target connective tissue growth factor in fibrotic lung diseases

Isshiki T, Naiel S, Vierhout M, Otsubo K, Ali P, Tsubouchi K, Yazdanshenas P, Kumaran V, Dvorkin-Gheva A, Kolb MRJ

Pharmacology and Therapeutics202452 citations
06

CD206+ macrophages are relevant non-invasive imaging biomarkers and therapeutic targets in experimental lung fibrosis

Pommerolle L, Beltramo G, Biziorek L, Truchi M, Dias AMM, Dondaine L, Tanguy J, Pernet N, Goncalves V, Bouchard A

Thorax202423 citations
07

A novel ex vivo approach for investigating profibrotic macrophage polarization using murine precision-cut lung slices

Vierhout M, Ayoub A, Ali P, Kumaran V, Naiel S, Isshiki T, Koenig JFE, Kolb MRJ, Ask K

Biochemical and Biophysical Research Communications20245 citationsSenior author
08

Novel roles of cardiac-derived erythropoietin in cardiac development and function

Allwood MA, Edgett BA, Platt MJ, Marrow JP, Coyle-Asbil B, Holjak EJB, Nelson VL, Bangali S, Alshamali R, Jacyniak K

Journal of Molecular and Cellular Cardiology20245 citations
09

Cardiomyocyte crosstalk with endothelium modulates cardiac structure, function, and ischemia-reperfusion injury susceptibility through erythropoietin

Marrow JP, Alshamali R, Edgett BA, Allwood MA, Cochrane KLS, Al-Sabbag S, Ayoub A, Ask K, Hare GMT, Brunt KR

Frontiers in Physiology20244 citations
10

Diagnostic potential of genomic blood biomarkers of pulmonary fibrosis in a prospective cohort

He D, Shannon CP, Hirota JA, Ask K, Ryerson CJ, Tebbutt SJ

PLoS ONE20241 citations

Courses taught

5
  • Independent Study in Medical Sciences

    MEDSCI 799 · last taught 2019

    Graduate
  • Demystifying Medicine

    HTHSCI 3DM3 · last taught 2023

    Undergraduate
  • Demystifying Research

    HTHSCI 3DR3 · last taught 2023

    Undergraduate
  • Demystifying Science - Advanced Knowledge Translation and Science Communication

    HTHSCI 4KT3 · last taught 2023

    Undergraduate
  • Demystifying Medicine

    HTHSCI 4DM3 · last taught 2022

    Undergraduate

Roles and appointments

  • Assistant Professor, Medicine, McMaster University (2011 - 2017)

Research institutes and memberships

  • McMaster Immunology Research Centre (MIRC)
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A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for
Subject: Prospective PhD student: Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Dear Professor Ask, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Modulating pro-fibrotic macrophages using yeast beta-glucan microparticles prepared by Pressurized Gas eXpanded liquid (PGX) Technology®" (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]
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