Faculty profile

Damu Tang

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Associate Professor (Part-Time)MedicineMcMaster University

Damu Tang

Associate Professor (Part-Time)

Medicine

Faculty of Health Sciences

McMaster University

Hamilton, Ontario, Canada

In this role since 2025

Email ORCID

Supervision signals

Adjunct, part-time and visiting faculty usually co-supervise alongside a core faculty member.
Teaches 1 graduate course, most recently in 2020.
16 publications in the last five years, latest in 2026.
Senior (last) author on 10 recent papers, a sign of leading a research group.
Principal investigator on 3 CIHR grants, most recently in 2018.

These signals come from public records. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

161

Publications

7,261

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Academic profiles

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Contact

damut@mcmaster.ca (905) 525-9140 ext. 35168

Research

Research areas, by share of publications

Cancer-related Molecular PathwaysMedicine
Prostate Cancer Treatment and ResearchMedicine
Cancer, Hypoxia, and MetabolismBiochemistry, Genetics and Molecular Biology
Cancer Cells and MetastasisMedicine

Research areas are derived from OpenAlex topics of their publications.

From the 150 most recent of 161 publications.

PCSK9 promotes prostate cancer via facilitating intratumoral cholesterol accumulation and enhancing immunosuppressive tumor microenvironment

Gu Y, Wei F, Dong Y, Lin X, Su Y, Wood G, Seidah NG, Bonert M, Werstuck G, Aziz T

Journal of Advanced Research20263 citations

DOI: 10.1016/j.jare.2026.04.020

SigRZ predicts the overall survival and disease progression in advanced renal cell carcinoma treated with the PD-1 inhibitor nivolumab

Dong Y, Mei W, Tang D

Asian Journal of Surgery2026Senior author

DOI: 10.1016/j.asjsur.2026.01.182

CYTH4 Facilitates Renal Cell Carcinoma via Enhancing Proliferation and Likely Immune Evasion

Dong Y, Su Y, Tang D

Biomolecules2026Senior author

DOI: 10.3390/biom16060923

The Sig27 multigene stratifies breast cancer fatality risk via reflecting tumor-associated immune suppressive features

Su Y, Dong Y, Zhang T, Tang D

Translational Oncology2026Senior author

DOI: 10.1016/j.tranon.2026.102820

A novel multigene panel (Sig27) robustly predicts poor prognosis of renal cell carcinoma via high-level associations with immunosuppressive features

Dong Y, Shayegan B, Su Y, Neira SV, Tang D

BJC Reports20256 citationsSenior author

DOI: 10.1038/s44276-025-00128-3

Peroxiredoxin 1 promotes intestinal inflammation by activating the NLRP3 inflammasome in macrophages through lysosomal disruption in Crohn’s disease

Li S, Xia Q, He Y, Wu W, Tang D, Deng Z, Zeng Z, Tu S, Chen B, Gu L

Cell Death and Disease20255 citations

DOI: 10.1038/s41419-025-07898-1

Sig27 stratifies prostate cancer recurrence by assessing the immunosuppressive properties of tumors.

Neira SV, Dong Y, Zhang T, Tang D

Endocrine-Related Cancer20253 citationsSenior author

DOI: 10.1530/erc-25-0326 PMID: W4415862069

Membranous Nephropathy Target Antigens Display Podocyte-Specific and Non-Specific Expression in Healthy Kidneys

Dong Y, Xu H, Tang D

Genes20253 citationsSenior author

DOI: 10.3390/genes16030241

Peroxiredoxin 1 aggravates acute kidney injury by promoting inflammation through Mincle/Syk/NF-κB signaling

Li S, Zhang Y, Lu R, Lv X, Lei Q, Tang D, Dai Q, Deng Z, Liao X, Tu S

Kidney International202388 citations

DOI: 10.1016/j.kint.2023.04.013

PCSK9 facilitates melanoma pathogenesis via a network regulating tumor immunity

Gu Y, Lin X, Dong Y, Wood G, Seidah NG, Werstuck G, Major P, Bonert M, Kapoor A, Tang D

Journal of Experimental and Clinical Cancer Research202342 citationsSenior authorOpen Access

DOI: 10.1186/s13046-022-02584-y PMID: W4313475622

Courses taught

Independent Study in Medical Sciences
MEDSCI 799 · last taught 2020
Graduate

Researchers with similar interests

Michael Levesque

Oncology

Cancer-related Molecular Pathways, Prostate Cancer Treatment and Research

Jean-claude Cutz

Pathology & Molecular Medicine

Cancer, Hypoxia, and Metabolism, Prostate Cancer Treatment and Research

Theos Tsakiridis

Oncology

Prostate Cancer Treatment and Research, Cancer, Hypoxia, and Metabolism

Gregory Pond

Oncology

Prostate Cancer Treatment and Research

Bobby Shayegan

Surgery

Prostate Cancer Treatment and Research

Sebastien Hotte

Oncology

Prostate Cancer Treatment and Research

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mention

Subject: Prospective PhD student: Cancer-related Molecular Pathways Dear Professor Tang, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "PCSK9 promotes prostate cancer via facilitating intratumoral cholesterol accumulation and enhancing immunosuppressive tumor microenvironment" (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

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Damu Tang

Research

PCSK9 promotes prostate cancer via facilitating intratumoral cholesterol accumulation and enhancing immunosuppressive tumor microenvironment

SigRZ predicts the overall survival and disease progression in advanced renal cell carcinoma treated with the PD-1 inhibitor nivolumab

CYTH4 Facilitates Renal Cell Carcinoma via Enhancing Proliferation and Likely Immune Evasion

The Sig27 multigene stratifies breast cancer fatality risk via reflecting tumor-associated immune suppressive features

A novel multigene panel (Sig27) robustly predicts poor prognosis of renal cell carcinoma via high-level associations with immunosuppressive features

Peroxiredoxin 1 promotes intestinal inflammation by activating the NLRP3 inflammasome in macrophages through lysosomal disruption in Crohn’s disease

Sig27 stratifies prostate cancer recurrence by assessing the immunosuppressive properties of tumors.

Membranous Nephropathy Target Antigens Display Podocyte-Specific and Non-Specific Expression in Healthy Kidneys

Peroxiredoxin 1 aggravates acute kidney injury by promoting inflammation through Mincle/Syk/NF-κB signaling

PCSK9 facilitates melanoma pathogenesis via a network regulating tumor immunity

Courses taught

Frequent collaborators

Alistair John Ingram

Jean-claude Cutz

Yingying Su

Michael Bonert

Joan Krepinsky

Tariq Aziz

Researchers with similar interests

Michael Levesque

Jean-claude Cutz

Theos Tsakiridis

Gregory Pond

Bobby Shayegan

Sebastien Hotte