Faculty profile

Jackek Michael Kwiecien

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Associate Professor (Part-Time)Pathology & Molecular MedicineMcMaster University

Research

Research areas, by share of publications

Research areas are derived from OpenAlex topics of their publications.

87 publications.

01

uPAR is highly expressed in recurrent glioblastoma and represents a candidate CAR T cell target

Maich WT, Shaikh MV, Puri A, Rossotti MA, Grewal S, Khanna A, Anand A, Mikolajewicz N, Seyfrid MP, McKenna DA

Science Translational Medicine20264 citations
02

Targeted Radionuclide Therapy Using a Lutetium-177 Labeled Human Anti-CD133 Antibody

Wyszatko K, Janzen N, Law N, Ventura M, Komal T, Savage N, Venugopal C, Kwiecien JM, Singh SK, Sadeghi S

Molecular Imaging and Biology20254 citations
03

Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells

Chokshi CR, Shaikh MV, Brakel B, Rossotti MA, Tieu D, Maich W, Anand A, Chafe SC, Zhai K, Suk Y

Nature Medicine202445 citations
04

Intratumoral Delivery of Chimeric Antigen Receptor T Cells Targeting CD133 Effectively Treats Brain Metastases.

Kieliszek AM, Mobilio D, Upreti D, Bloemberg D, Escudero L, Kwiecien JM, Alizada Z, Zhai K, Ang P, Chafe SC

Clinical Cancer Research202426 citations
05

Photoacoustic imaging of a cyanine dye targeting bacterial infection

Swann R, Hernández-Valdés D, Silva LR, Marfatia YM, El-Zaria ME, Genady AR, Kwiecien JM, Valliant JF, Sadeghi S

Scientific Reports20246 citations
06

Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice

Desjardins EM, Wu J, Lavoie DCT, Ahmadi E, Townsend LK, Morrow MR, Wang D, Tsakiridis EE, Batchuluun B, Fayyazi R

Cell Reports Medicine202339 citations
07

Functional dissection and assembly of a small, newly evolved, W chromosome-specific genomic region of the African clawed frog Xenopus laevis

Cauret CMS, Jordan DC, Kukoly LM, Burton SR, Anele EU, Kwiecien JM, Gansauge M-T, Senthillmohan S, Greenbaum E, Meyer M

PLoS Genetics202311 citationsOpen Access
08

Development of a new surgical technique to infuse kynurenic acid to optic nerves in chickens for studying loss of myelination

Gurdita A, Kwiecien JM, Choh V

Trials in Vaccinology20231 citations
09

Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia

Morrow MR, Batchuluun B, Wu J, Ahmadi E, Leroux JM, Mohammadi-Shemirani P, Desjardins EM, Wang Z, Tsakiridis EE, Lavoie DCT

Cell Metabolism2022200 citations
10

Barriers to axonal regeneration after spinal cord injury: a current perspective

Kwiecien JM

Neural Regeneration Research20229 citationsFirst author
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Subject: Prospective PhD student: Spinal Cord Injury Research Dear Professor Kwiecien, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "uPAR is highly expressed in recurrent glioblastoma and represents a candidate CAR T cell target" (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]
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