Faculty profile

Jianhan Wu

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nullMcMaster University

Jianhan Wu

null

Faculty of Health Sciences

McMaster University

Hamilton, Ontario, Canada

Email ORCID

Supervision signals

This is a research or leadership role; ask the department whether it includes supervision.
No graduate courses on record.
8 publications in the last five years, latest in 2025.

These signals come from public records. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

509

Citations

h-index

Collaborators

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Academic profiles

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Contact

wuj95@mcmaster.ca

Research

Research areas, by share of publications

Liver Disease Diagnosis and TreatmentMedicine
Chronic Kidney Disease and DiabetesMedicine

Research areas are derived from OpenAlex topics of their publications.

13 publications.

ACLY inhibition promotes tumour immunity and suppresses liver cancer

Gautam J, Wu J, Lally JSV, McNicol JD, Fayyazi R, Ahmadi E, Oniciu DC, Heaton S, Newton RS, Rehal S

Nature2025

DOI: 10.1038/s41586-025-09297-0

Kidney Volume and Risk of Incident Kidney Outcomes

Wu J, Wang Y, Vlasschaert C, Lali R, Feiner J, Gaheer P, Yang S, Perrot N, Chong M, Paré G

Journal of the American Society of Nephrology202411 citationsFirst author

DOI: 10.1681/asn.0000000000000419

Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non‐small cell lung cancer (NSCLC) through inhibition of HIF‐1α

Biziotis O, Tsakiridis EE, Ali A, Ahmadi E, Wu J, Wang S, Mekhaeil B, Singh K, Menjolian G, Farrell T

Molecular Oncology202340 citations

DOI: 10.1002/1878-0261.13508

The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy

Ali A, Mekhaeil B, Biziotis OD, Tsakiridis EE, Ahmadi E, Wu J, Wang S, Singh K, Menjolian G, Farrell T

Communications Biology202339 citationsOpen Access

DOI: 10.1038/s42003-023-05289-w PMID: W4386545412

Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice

Desjardins EM, Wu J, Lavoie DCT, Ahmadi E, Townsend LK, Morrow MR, Wang D, Tsakiridis EE, Batchuluun B, Fayyazi R

Cell Reports Medicine202339 citations

DOI: 10.1016/j.xcrm.2023.101193

Metformin-induced reductions in tumor growth involves modulation of the gut microbiome

Broadfield LA, Saigal A, Szamosi JC, Hammill JA, Bezverbnaya K, Wang D, Gautam J, Tsakiridis EE, Di Pastena F, McNicol J

Molecular Metabolism2022

Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia

Morrow MR, Batchuluun B, Wu J, Ahmadi E, Leroux JM, Mohammadi-Shemirani P, Desjardins EM, Wang Z, Tsakiridis EE, Lavoie DCT

Cell Metabolism2022200 citations

DOI: 10.1016/j.cmet.2022.05.004

Metformin-induced reductions in tumor growth involves modulation of the gut microbiome

Broadfield LA, Saigal A, Szamosi JC, Hammill JA, Bezverbnaya K, Wang D, Gautam J, Tsakiridis EE, Di Pastena F, McNicol J

Molecular Metabolism202264 citations

DOI: 10.1016/j.molmet.2022.101498

The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue

Wang B, Tsakiridis EE, Zhang S, Llanos A, Desjardins EM, Yabut JM, Green AE, Day EA, Smith BK, Lally JSV

Nature Communications202172 citationsOpen Access

DOI: 10.1038/s41467-021-25384-y PMID: W3194507827

Bone cancer-induced pain is associated with glutamate signalling in peripheral sensory neurons

Zhu YF, Linher-Melville K, Wu J, Fazzari J, Miladinovic T, Ungard R, Zhu KL, Singh G

Molecular Pain202026 citations

DOI: 10.1177/1744806920911536

Courses taught

Research Project in Computational Biology
HTHSCI 3CP3 · last taught 2026
Undergraduate
Introduction to Computational Biology
HTHSCI 3CB3 · last taught 2025
Undergraduate
Inquiry III: Advanced Inquiry in Health Sciences
HTHSCI 3E03 · last taught 2023
Undergraduate

Researchers with similar interests

Maryam Moini

Medicine

Liver Disease Diagnosis and Treatment

Jimin (Nancy) Liu

Pathology & Molecular Medicine

Liver Disease Diagnosis and Treatment

Melanie Ferri

Medical Imaging

Liver Disease Diagnosis and Treatment

Joan Krepinsky

Medicine

Chronic Kidney Disease and Diabetes

Catherine Clase

Medicine

Chronic Kidney Disease and Diabetes

Amber Molnar

Medicine

Chronic Kidney Disease and Diabetes

Write to this professor

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Paper to mention

Subject: Prospective PhD student: Liver Disease Diagnosis and Treatment Dear Professor Wu, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "ACLY inhibition promotes tumour immunity and suppresses liver cancer" (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

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Jianhan Wu

Research

ACLY inhibition promotes tumour immunity and suppresses liver cancer

Kidney Volume and Risk of Incident Kidney Outcomes

Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non‐small cell lung cancer (NSCLC) through inhibition of HIF‐1α

The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy

Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice

Metformin-induced reductions in tumor growth involves modulation of the gut microbiome

Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia

Metformin-induced reductions in tumor growth involves modulation of the gut microbiome

The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue

Bone cancer-induced pain is associated with glutamate signalling in peripheral sensory neurons

Courses taught

Frequent collaborators

Gregory Steinberg

Theos Tsakiridis

Paola Muti

Jonathan Bramson

Dongdong Wang

Guillaume Pare

Researchers with similar interests

Maryam Moini

Jimin (Nancy) Liu

Melanie Ferri

Joan Krepinsky

Catherine Clase

Amber Molnar