Faculty profile

Martin R Stampfli

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Professor EmeritusPathology & Molecular MedicineMcMaster University

Research

The goal of my research program is to understand how environmental and infectious agents, alone or in combination, influence innate and adaptive immune responses in the respiratory tract and the contribution of these changes to the pathogenesis of respiratory disorders such as chronic obstructive pulmonary disease (COPD) and asthma.

Research areas, by share of publications

Research areas are derived from OpenAlex topics of their publications.

From the 150 most recent of 178 publications.

01

Endothelial dysfunction drives atherosclerotic plaque macrophage-dependent abdominal aortic aneurysm formation

Thayaparan D, Emoto T, Khan AB, Besla R, Hamidzada H, El-Maklizi M, Sivasubramaniyam T, Vohra S, Hagerman A, Nejat S

Nature Immunology202541 citations
02

Serum Immunoglobulin G Levels Are Associated with Risk for Exacerbations: An Analysis of SPIROMICS

Burnim M, Putcha N, LaFon D, Woo H, Azar A, Groenke L, Stampfli M, Schaub A, Fawzy A, Balasubramanian A

American Journal of Respiratory and Critical Care Medicine20259 citations
03

Cannabis smoke suppresses antiviral immune responses to influenza A in mice

Milad N, Fantauzzi MF, McGrath JJC, Cass SP, Thayaparan D, Wang P, Afkhami S, Aguiar JA, Ask K, Doxey AC

ERJ Open Research202310 citationsOpen Access
04

Multi-omics analyses of airway host–microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions

Yan Z, Chen B, Yang Y, Yi X, Wei M, Ecklu-Mensah G, Buschmann MM, Liu H, Gao J, Liang W

Nature Microbiology2022236 citations
05

Inflammatory Endotype-Associated Airway Resistome in Chronic Obstructive Pulmonary Disease

Yi X, Li Y, Liu H, Liu X, Yang J, Gao J, Yang Y, Liang Z, Wang F, Chen D

Microbiology Spectrum202222 citations
06

Effects of Traffic-Related Air Pollution on Exercise Endurance, Dyspnea, and Cardiorespiratory Responses in Health and COPD A Randomized, Placebo-Controlled, Crossover Trial

Syed N, Ryu MH, Dhillon S, Schaeffer MR, Ramsook AH, Leung JM, Ryerson CJ, Carlsten C, Guenette JA, Network CRR

Chest202214 citations
07

Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar–capillary barrier function during influenza infection

McGrath JJC, Vanderstocken G, Dvorkin-Gheva A, Cass SP, Afkhami S, Fantauzzi MF, Thayaparan D, Reihani A, Wang P, Beaulieu A

European Respiratory Journal202214 citations
08

Cigarette smoke exposure attenuates the induction of antigen-specific IgA in the murine upper respiratory tract

McGrath JJC, Thayaparan D, Cass SP, Mapletoft JP, Zeng PYF, Koenig JFE, Fantauzzi MF, Bagri P, Ly B, Heo R

Mucosal Immunology202114 citationsOpen Access
09

Increased Monocyte-Derived CD11b+ Macrophage Subpopulations Following Cigarette Smoke Exposure Are Associated With Impaired Bleomycin-Induced Tissue Remodelling

Cass SP, Mekhael O, Thayaparan D, McGrath JJC, Revill SD, Fantauzzi MF, Wang P, Reihani A, Hayat AI, Stevenson CS

Frontiers in Immunology202114 citations
10

Development and validation of a mouse model of contemporary cannabis smoke exposure

Fantauzzi MF, Cass SP, McGrath JJC, Thayaparan D, Wang P, Stampfli MR, Hirota JA

ERJ Open Research202111 citationsOpen Access

Courses taught

1
  • Introductory Immunology

    HTHSCI 3I03 · last taught 2019

    Undergraduate

Research institutes and memberships

  • McMaster Immunology Research Centre (MIRC)
  • Michael G. DeGroote Centre for Medicinal Cannabis Research (Joint Institute)
Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for
Subject: Prospective PhD student: Asthma and respiratory diseases Dear Professor Stampfli, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Endothelial dysfunction drives atherosclerotic plaque macrophage-dependent abdominal aortic aneurysm formation" (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]
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