Eva Kaufmann, Queen's University

Research

Trained Immunity Cell-Based Therapy Fungal Infections Immunology Immunosuppression Innate Immune Memory Allergy Epigenetic Reprogramming

Latest papers

Trained Immunity in Childhood Vaccination.
Acta paediatrica (Oslo, Norway : 1992) · 2026 · senior author
Evolution and development of innate immune memory.
Science immunology · 2026 · senior author
Sensory neuron production of substance P and TAFA4 promotes disease tolerance during viral infection.
Immunity · 2026

All 18 publications

Latest funding

SHIELDing life: enhancing trained immunity against fungal threats
CIHR · 2024 · Nominated PI
$500,000
Targeting innate immune memory for prevention of asthma
CIHR · 2024 · Nominated PI
$100,000
Wildfire Particles Exacerbate Asthma by Increasing Inflammation Through Neural and Microbial Alterations
CIHR · 2023 · Principal investigator
$1,875,000

All 4 grants and awards

18 publications.

01

Trained Immunity in Childhood Vaccination.

Cai C, Hossenbaccus L, Kaufmann E

Acta paediatrica (Oslo, Norway : 1992)2026Senior author

DOI: 10.1111/apa.70751 PMID: 42770653

02

Evolution and development of innate immune memory.

Divangahi M, Kaufmann E

Science immunology2026Senior author

DOI: 10.1126/sciimmunol.aeb7976 PMID: 42397938

03

Sensory neuron production of substance P and TAFA4 promotes disease tolerance during viral infection.

Roger A, Fohrer T, Mardelle U, Thomas I, Nezhad ST, Gupta S, Dory A, Jeyanathan V, Liaghat A, Mielle J, Khlifi HM, Santamaria JC, Brunet E, Gouilly J, Escaliere B, Bretaud N, Crosson T, Barbon PV, Mossadegh-Keller N, Irla M, Basta S, Broggi A, Milpied P, Gour N, Feuillet V, Hoeffel G, Dong X, Kaufmann E, Reynders A, Talbot S, Moqrich A, Ugolini S

Immunity2026

DOI: 10.1016/j.immuni.2026.01.022 PMID: 41747735

04

Basophils activate oncostatin M receptor-expressing vagal sensory neurons.

Wang JC, Park K, Roger A, Nikpoor AR, Crosson T, Sunwoo HJ, Kaufmann E, Rafei M, Chang EH, Talbot S

The Journal of allergy and clinical immunology2026

DOI: 10.1016/j.jaci.2025.10.027 PMID: 41207641

05

Evolving our understanding of trained immunity.

Kaufmann E, Sohrabi Y, Domínguez-Andrés J, Novakovic B, Netea MG, van der Meer JWM

eLife2025First author

DOI: 10.7554/elife.106029 PMID: 41190945

06

Hematopoietic stem and progenitor cells as a reservoir for trained immunity.

Tran BT, Jeyanathan V, Cao R, Kaufmann E, King KY

eLife2025

DOI: 10.7554/elife.106610 PMID: 40905954

07

Psychological Stress-Induced Local Immune Response to Food Antigens Increases Pain Signaling Across the Gut in Mice.

Aguilera-Lizarraga J, Lopez-Lopez C, Jaramillo-Polanco J, Florens MV, Yu Y, Tsang QK, Chakraborty A, De Gand S, Pia F, Quan R, Cuende-Estévez M, Van Remoortel S, Strid J, Lomax AE, Berin MC, Craig AW, Kaufmann E, Ormiston ML, Vanner SJ, Hussein H, Boeckxstaens GE, Reed DE

Gastroenterology2025

DOI: 10.1053/j.gastro.2025.01.246 PMID: 39978560

08

Author Correction: β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus.

Khan N, Tran KA, Chevre R, Locher V, Richter M, Sun S, Sadeghi M, Pernet E, Herrero-Cervera A, Grant A, Saif A, Downey J, Kaufmann E, Khader SA, Joubert P, Barreiro LB, Yipp BG, Soehnlein O, Divangahi M

Nature immunology2025

DOI: 10.1038/s41590-025-02099-6 PMID: 39920361

09

Characterization of SARS-CoV-2 Entry Genes in Skeletal Muscle and Impacts of In Vitro Versus In Vivo Infection.

Bhattarai S, Kaufmann E, Liang F, Zheng Y, Gusev E, Hamid Q, Ding J, Divangahi M, Petrof BJ

Journal of cachexia, sarcopenia and muscle2025

DOI: 10.1002/jcsm.13705 PMID: 39871399

10

β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus.

Khan N, Tran KA, Chevre R, Locher V, Richter M, Sun S, Sadeghi M, Pernet E, Herrero-Cervera A, Grant A, Saif A, Downey J, Kaufmann E, Khader SA, Joubert P, Barreiro LB, Yipp BG, Soehnlein O, Divangahi M

Nature immunology2025

DOI: 10.1038/s41590-024-02041-2 PMID: 39779870

SHIELDing life: enhancing trained immunity against fungal threats

Nominated PICIHR2024Operating Grant: 17th JPIAMR transnational call for research projects (2024)

Principal investigators: Kaufmann, Eva

Keywords: Cell-Based Therapy; Fungal Infections; Immunology; Immunosuppression; Innate Immune Memory; Trained Immunity

$500,000

Targeting innate immune memory for prevention of asthma

Nominated PICIHR2024Project Grant - Priority Announcement: Infection and Immunity

Principal investigators: Kaufmann, Eva

Keywords: Allergy; Epigenetic Reprogramming; Hematopoietic Stem And Progenitor Cells; Innate Immunity; Mouse Models; Trained Immunity; Vaccination

$100,000

Wildfire Particles Exacerbate Asthma by Increasing Inflammation Through Neural and Microbial Alterations

Principal investigatorCIHR2023Team Grant: Lung Health - Inflammation and Lung Health

Principal investigators: Kubes, Paul; Jull, Janet E; Kaufmann, Eva; Leigh, Richard; Talbot, Sébastien; Thornton, Christina S; Zhao, Ran

Keywords: Asthma; Eosinophils; Imaging; Inflammation; Lung; Microbiome; Neuroinflammation; Neutrophils; Trained Immunity; Wildfires

$1,875,000

Canada Research Chairs - Tier 2

Nominated PICIHR2022Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Kaufmann, Eva

Keywords: Crc

$600,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biomedical and Molecular Sciences
Medicine
Meakins-Christie Laboratories
Microbiology and Immunology
Microbiology
Physiology and Pharmacology
Other

Co-authors at Queen's University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Eva Kaufmann

Faculty

13 shared papers, latest 2026

Maziar Divangahi

Medicine

9 shared papers, latest 2026

Jun Ding

Meakins-Christie Laboratories

3 shared papers, latest 2025

Sébastien Talbot

Biomedical and Molecular Sciences

2 shared papers, latest 2026

Philippe Joubert

Faculty

2 shared papers, latest 2025

Nargis Khan

Microbiology and Immunology

2 shared papers, latest 2025

Nader Ghasemlou

Biomedical and Molecular Sciences

1 shared papers, latest 2024

Moutih Rafei

Physiology and Pharmacology

1 shared papers, latest 2026

Moutih Rafei

Microbiology

1 shared papers, latest 2026

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2024

Subject: Prospective PhD student: Trained Immunity Dear Professor Kaufmann, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Trained Immunity in Childhood Vaccination." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "SHIELDing life: enhancing trained immunity against fungal threats" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Eva Kaufmann

Research

Latest papers

Latest funding

Trained Immunity in Childhood Vaccination.

Evolution and development of innate immune memory.

Sensory neuron production of substance P and TAFA4 promotes disease tolerance during viral infection.

Basophils activate oncostatin M receptor-expressing vagal sensory neurons.

Evolving our understanding of trained immunity.

Hematopoietic stem and progenitor cells as a reservoir for trained immunity.

Psychological Stress-Induced Local Immune Response to Food Antigens Increases Pain Signaling Across the Gut in Mice.

Author Correction: &#x3b2;-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus.

Characterization of SARS-CoV-2 Entry Genes in Skeletal Muscle and Impacts of In&#xa0;Vitro Versus In&#xa0;Vivo Infection.

&#x3b2;-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus.

SHIELDing life: enhancing trained immunity against fungal threats

Targeting innate immune memory for prevention of asthma

Wildfire Particles Exacerbate Asthma by Increasing Inflammation Through Neural and Microbial Alterations

Canada Research Chairs - Tier 2

Frequent collaborators

Eva Kaufmann

Maziar Divangahi

Jun Ding

Sébastien Talbot

Philippe Joubert

Nargis Khan

Nader Ghasemlou

Moutih Rafei

Moutih Rafei

Author Correction: β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus.

Characterization of SARS-CoV-2 Entry Genes in Skeletal Muscle and Impacts of In Vitro Versus In Vivo Infection.

β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus.