Maziar Divangahi, McGill University

Research

Trained Immunity Immune Response Respiratory Infection Innate Immunity Influenza Virus Adaptive Immunity Cell Death Program Eicosanoids

Latest papers

Maladaptive trained immunity as a hematopoietic stem cell driver of inflammaging.
Nature aging · 2026 · first author
Innate immunity at the crossroads of protection and pathology: insights from the Aegean.
Nature immunology · 2026
Neutrophil-T cell dynamics predict tuberculosis outcome.
Trends in immunology · 2026 · first author

All 113 publications

Latest funding

International Conference on Innate Immune Memory
CIHR · 2025 · Nominated PI
$20,000
Canada Research Chair - Tier 1
CIHR · 2025 · Nominated PI
$1,400,000
Harnessing the power of trained immunity in disease tolerance against influenza virus
CIHR · 2025 · Nominated PI
$1,304,325

All 29 grants and awards

113 publications.

01

Maladaptive trained immunity as a hematopoietic stem cell driver of inflammaging.

Divangahi M, King KY

Nature aging2026First author

DOI: 10.1038/s43587-026-01197-w PMID: 42576025

02

Innate immunity at the crossroads of protection and pathology: insights from the Aegean.

Hajishengallis G, Chavakis T, Divangahi M, Murray PJ, Walmsley S

Nature immunology2026

DOI: 10.1038/s41590-026-02601-8 PMID: 42463558

03

Neutrophil-T cell dynamics predict tuberculosis outcome.

Divangahi M, Schurr E

Trends in immunology2026First author

DOI: 10.1016/j.it.2026.08.010 PMID: 42660718

04

Evolution and development of innate immune memory.

Divangahi M, Kaufmann E

Science immunology2026First author

DOI: 10.1126/sciimmunol.aeb7976 PMID: 42397938

05

Spatially Distinct Bone Marrow Sites Are Asymmetrically Impacted by Inflammatory Cardiovascular Disease.

Deckers J, van Elsas Y, Versteeg I, Anbergen T, Toner YC, Grao-Roldán C, Cole JE, Umali M, Wang W, Nauta S, Demkiw KM, Pérez-Medina C, van Leent MMT, Teunissen AJP, Fayad ZA, Joosten LAB, Swirski FK, Nahrendorf M, Divangahi M, Riksen NP, Netea MG, van der Meel R, Monaco C, Lutgens E, Beldman TJ, Mulder WJM

JACC. Basic to translational science2026

DOI: 10.1016/j.jacbts.2026.101660 PMID: 42748518

06

TGFβ-PDL1 signaling in neutrophils preserves lung barrier during hyperinflammation.

Li Z, Moore AR, Zheng H, Karunamurthy J, Bhagrath A, Li J, Young D, Jurado LF, Couto K, Kulle A, Park H, Kwak A, Belur V, Talbot S, Divangahi M, DiGiandomenico A, Rogers A, Cohen TS, Ehrlicher AJ, Mandl JN, Wang J, Dufour A, Khatri P, Thanabalasuriar A

Blood2026

DOI: 10.1182/blood.2025031635 PMID: 42154905

07

Revisiting T cells: Innate actions and emerging links to innate memory response.

Tran KA, Divangahi M

Journal of immunology (Baltimore, Md. : 1950)2026Senior author

DOI: 10.1093/jimmun/vkag001 PMID: 41861096

08

A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection

Westfall S, Gentile ME, Olsen TM, Karo-Atar D, Bogza A, Röstel F, Pardy RD, Mandato G, Fontes G, Herbert D

Cell202518 citations

DOI: 10.1016/j.cell.2025.03.043

09

Cellular and Molecular Mechanisms of Innate Memory Responses.

Mhlanga MM, Fanucchi S, Ozturk M, Divangahi M

Annual review of immunology2025Senior author

DOI: 10.1146/annurev-immunol-101721-035114 PMID: 40279311

10

Author Correction: β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus.

Khan N, Tran KA, Chevre R, Locher V, Richter M, Sun S, Sadeghi M, Pernet E, Herrero-Cervera A, Grant A, Saif A, Downey J, Kaufmann E, Khader SA, Joubert P, Barreiro LB, Yipp BG, Soehnlein O, Divangahi M

Nature immunology2025Senior author

DOI: 10.1038/s41590-025-02099-6 PMID: 39920361

International Conference on Innate Immune Memory

Nominated PICIHR2025Planning and Dissemination Grant - Institute Community Support

Principal investigators: Divangahi, Maziar

Keywords: Career Development; Host Defense Mechanisms; Novel Immunotherapies; Trained Immunity; Training; Vaccines

$20,000

Canada Research Chair - Tier 1

Nominated PICIHR2025Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Divangahi, Maziar

Keywords: Crc

$1,400,000

Harnessing the power of trained immunity in disease tolerance against influenza virus

Nominated PICIHR2025Project Grant

Principal investigators: Divangahi, Maziar

Keywords: Disease Tolearnce; Influenza Virus; Trained Immunity

$1,304,325

Identifying Correlates of Protection Against TB for Novel Vaccine Development

Nominated PICIHR2025Project Grant

Principal investigators: Divangahi, Maziar

Keywords: Tb Vaccine

$1,369,350

Unlocking the Power of Trained Immunity in Cancer

Nominated PICIHR2025Team Grant: Bringing Biology to Cancer Prevention - Vaccines

Principal investigators: Divangahi, Maziar; McPherson, Victor A; Muller, William J; Thanabalasuriar, Ajitha

Keywords: Cancer; Trained Immunity

$1,500,000

Programming Innate Memory Responses to promote host defense against SARS-CoV-2 Pneumonia

Nominated PICIHR2024Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Divangahi, Maziar

Keywords: Covid-19; Disease Tolerance; Trained Immunity

$100,000

Targeting unconventional T cells in early life to enhance immunity against tuberculosis

SupervisorCIHR2022CIHR Fellowship

Principal investigators: Ahmed, Mohamed

Keywords: Gut Micriobiota; Human Immunology; Infectious Diseases; Neonates; Respiratory Infections; Tuberculosis; Vaccines

$135,000

Determinants of susceptibility to influenza infection in pregnant mice

Co-investigatorCIHR2022Project Grant

Principal investigators: Martin, James G

Keywords: Allogeneic; Epithelium; Influenza A; Innate Lymphoid Cells; Interleukin 33; Macrophage; Murine Model; Syngeneic

$768,825

Developing a novel vaccine against COVID-19

Nominated PICIHR2020Operating Grant: COVID-19 - Project Grant

Principal investigators: Divangahi, Maziar

Keywords: Immune Response; Respiratory Infection

$569,925

Deciphering the Implementability of Epigenetic Reprogramming in Hematopoietic Stem Cells as a Novel Vaccination Strategy against Human Tuberculosis

SupervisorCIHR2019CIHR Fellowship

Principal investigators: Kaufmann, Eva

Keywords: Bcg; Hematopoietic Stem Cells; Humanized Mice; Innate Immune System; Mouse Models; Mycobacterium Tuberculosis; Trained Immunity; Tuberculosis; Vaccination

$135,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Microbiology and Immunology
Biomedical and Molecular Sciences
Meakins-Christie Laboratories
Physiology
Microbiology and Infectious Diseases
Pediatrics
Other

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Eva Kaufmann

Faculty

23 shared papers, latest 2026

Eva Kaufmann

Biomedical and Molecular Sciences

9 shared papers, latest 2026

Jun Ding

Meakins-Christie Laboratories

5 shared papers, latest 2025

Ajitha Thanabalasuriar

Medicine

4 shared papers, latest 2026

Philippe Joubert

Faculty

4 shared papers, latest 2025

Nargis Khan

Microbiology and Immunology

3 shared papers, latest 2025

Erwin Schurr

Medicine

3 shared papers, latest 2026

Salman Qureshi

Medicine

3 shared papers, latest 2017

Antoine Dufour

Microbiology and Infectious Diseases

2 shared papers, latest 2026

Alex Gregorieff

Faculty

2 shared papers, latest 2025

Danuta Radzioch

Biomedical Engineering

2 shared papers, latest 2015

Julianna Blagih

Obstetrics and Gynecology

2 shared papers, latest 2018

Anastasia Nijnik

Physiology

2 shared papers, latest 2020

Zhou Xing

Medicine

2 shared papers, latest 2014

Bruce Mazer

Pediatrics

2 shared papers, latest 2020

Annie Rochette

Occupational Therapy

1 shared papers, latest 2023

Sachiko Sato

Infection and Immunology

1 shared papers, latest 2020

Joyce Rauch

Medicine

1 shared papers, latest 2019

Janusz Rak

Pediatrics

1 shared papers, latest 2022

David Langlais

Rheumatology

1 shared papers, latest 2024

Braedon McDonald

Medicine

1 shared papers, latest 2022

Yue Li

Epidemiology and Biostatistics

1 shared papers, latest 2020

Jerry Pelletier

Biochemistry

1 shared papers, latest 2015

Jun Liu

Molecular Genetics

1 shared papers, latest 2021

Simon Rousseau

Faculty

1 shared papers, latest 2014

Connie Krawczyk

Microbiology and Immunology

1 shared papers, latest 2022

Philippe Gros

Biochemistry

1 shared papers, latest 2008

Karen Mossman

Medicine

1 shared papers, latest 2022

Christina Haston

Medicine

1 shared papers, latest 2009

Josh Koenig

Medicine

1 shared papers, latest 2025

Madhukar Pai

Medicine

1 shared papers, latest 2016

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Trained Immunity Dear Professor Divangahi, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Maladaptive trained immunity as a hematopoietic stem cell driver of inflammaging." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "International Conference on Innate Immune Memory" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Maziar Divangahi

Research

Latest papers

Latest funding

Maladaptive trained immunity as a hematopoietic stem cell driver of inflammaging.

Innate immunity at the crossroads of protection and pathology: insights from the Aegean.

Neutrophil-T cell dynamics predict tuberculosis outcome.

Evolution and development of innate immune memory.

Spatially Distinct Bone Marrow Sites Are Asymmetrically Impacted by Inflammatory Cardiovascular Disease.

TGF&#x3b2;-PDL1 signaling in neutrophils preserves lung barrier during hyperinflammation.

Revisiting T cells: Innate actions and emerging links to innate memory response.

A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection

Cellular and Molecular Mechanisms of Innate Memory Responses.

Author Correction: &#x3b2;-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus.

Frequent collaborators

Eva Kaufmann

Eva Kaufmann

Jun Ding

Ajitha Thanabalasuriar

Philippe Joubert

Nargis Khan

Erwin Schurr

Salman Qureshi

Antoine Dufour

Alex Gregorieff

Danuta Radzioch

Julianna Blagih

Anastasia Nijnik

Zhou Xing

Bruce Mazer

Annie Rochette

Sachiko Sato

Joyce Rauch

Janusz Rak

David Langlais

Braedon McDonald

Yue Li

Jerry Pelletier

Jun Liu

Simon Rousseau

Connie Krawczyk

Philippe Gros

Karen Mossman

Christina Haston

Josh Koenig

Madhukar Pai

TGFβ-PDL1 signaling in neutrophils preserves lung barrier during hyperinflammation.

Author Correction: β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus.