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Research
Latest papers
Characterization of Conformational Dynamics and Structural Plasticity of the Catalytic Domain of Human Mitochondrial YME1L Protease.
Biochemistry · 2026 · senior author
NMR Insights Into the Structural Dynamics of p47, A Key Adaptor Protein of p97 in Golgi Reassembly.
Journal of molecular biology · 2025 · senior author
1H, 13C, and 15N backbone resonance assignments of full-length and a SIM-SEP-containing fragment (101-266) of p47, a p97 adaptor protein.
Biomolecular NMR assignments · 2025 · senior author
Latest funding
- $185,000
Structural and dynamic insights into the mechanisms of mitochondrial AAA proteases
NSERC · 2020 · Principal investigator
- $12,500
Structural and dynamic insights into the mechanisms of mitochondrial AAA proteases
NSERC · 2020 · Principal investigator
6 publications.
Characterization of Conformational Dynamics and Structural Plasticity of the Catalytic Domain of Human Mitochondrial YME1L Protease.
Black MK, Kim A, Chen CY, Goncalves MM, Waseem S, Vahidi S, Huang R
NMR Insights Into the Structural Dynamics of p47, A Key Adaptor Protein of p97 in Golgi Reassembly.
Black MK, Raseekan R, Kanters P, Kim P, Huang R
1H, 13C, and 15N backbone resonance assignments of full-length and a SIM-SEP-containing fragment (101-266) of p47, a p97 adaptor protein.
Raseekan R, Black MK, Huang R
Allosteric regulation of proteolytic machines unveiled by the synergy between cryo-EM and solution NMR spectroscopy.
Turner M, Harkness RW, Ripstein ZA, Huang R, Vahidi S
Autoinhibition of ubiquitin-specific protease 8: Insights into domain interactions and mechanisms of regulation.
Caba C, Black M, Liu Y, DaDalt AA, Mallare J, Fan L, Harding RJ, Wang YX, Vacratsis PO, Huang R, Zhuang Z, Tong Y
Probing Cooperativity of N-Terminal Domain Orientations in the p97 Molecular Machine: Synergy Between NMR Spectroscopy and Cryo-EM.
Huang R, Ripstein ZA, Rubinstein JL, Kay LE
Structural and dynamic insights into the mechanisms of mitochondrial AAA proteases
Principal investigators: Huang, Rui
Keywords: mitochondrial protein; protein nmr spectroscopy; protein quality control; methyl-trosy nmr; protein dynamics; allostery; aaa protein; protein degradation; aaa protease; atpase
Structural and dynamic insights into the mechanisms of mitochondrial AAA proteases
Principal investigators: Huang, Rui
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Siavash Vahidi and Rui Huang: 2 shared papers
- Yufeng Tong and Rui Huang: 1 shared paper
- Rui Huang and Peter Kim: 1 shared paper
- Chemistry
- Molecular and Cellular Biology
- Mathematics and Statistics
- Pharmacology and Toxicology
Co-authors at University of Guelph, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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