Shayan Sharif, University of Guelph

Research

Edi

Latest papers

A novel Bacillus subtilis strain alleviates necrotic enteritis in chickens by reducing NetB toxin from Clostridium perfringens.
Poultry science · 2026
Modulation of gut immunity and microbiota by Bacteroides thetaiotaomicron confers dose-dependent protection against necrotic enteritis in broiler chickens.
Poultry science · 2026
Transcriptomic profiling reveals early immune activation and metabolic remodeling in lymphoid tissues following in ovo Marek's disease virus mRNA vaccination in chickens.
Veterinary immunology and immunopathology · 2026 · senior author

All 209 publications

Latest funding

Canada Research Chairs Program Institutional Equity Stipend
CIHR · 2025 · Nominated PI
$19,500
The Canadian One Health Training Program on Emerging Zoonoses
CIHR · 2024 · Co-investigator
$2,700,000
The H5Nx Genomic Landscape: Predictive Modelling of Host and Antigenic Transitions
CIHR · 2024 · Co-investigator

All 32 grants and awards

From the 150 most recent of 209 publications.

01

A novel Bacillus subtilis strain alleviates necrotic enteritis in chickens by reducing NetB toxin from Clostridium perfringens.

Dayem SB, Yu H, Alizadeh M, Cheung J, Tolooe A, Lepp D, Boodhoo N, Sharif S, Gong J

Poultry science2026

DOI: 10.1016/j.psj.2026.107264 PMID: 42501545

02

Modulation of gut immunity and microbiota by Bacteroides thetaiotaomicron confers dose-dependent protection against necrotic enteritis in broiler chickens.

Alizadeh M, Oladokun S, Fazel F, Fletcher C, Blake K, Sharif S, Rodriguez-Lecompte JC

Poultry science2026

DOI: 10.1016/j.psj.2026.106480 PMID: 41570523

03

Transcriptomic profiling reveals early immune activation and metabolic remodeling in lymphoid tissues following in ovo Marek's disease virus mRNA vaccination in chickens.

Shoja Doost J, Yitbarek A, Wootton SK, Behboudi S, Sharif S

Veterinary immunology and immunopathology2026Senior author

DOI: 10.1016/j.vetimm.2025.111052 PMID: 41468646

04

Quantitative risk assessment of avian influenza: A scoping review.

Khoshbazm M, Spence K, Soltani M, Grant L, Yan Y, Sharif S, Dara R

Infectious Disease Modelling2026

DOI: 10.1016/j.idm.2026.04.013 PMID: 42339283

05

Evaluating transient risk factors for avian influenza outbreaks in Canada using case-crossover study and machine learning.

Sekhavati I, Dara R, Sharif S, Aliabadi AA

Poultry science2026

DOI: 10.1016/j.psj.2026.107364 PMID: 42546427

06

Examining the Threat of H5N1 Highly Pathogenic Avian Influenza to Human Health.

Blais-Savoie J, Halajian E, Nirmalarajah K, Banete A, Corredor JC, Kotwa JD, Lee Y, Raj S, Sharif S, Mideo N, Mubareka S

Chest2026

DOI: 10.1016/j.chest.2025.10.030 PMID: 41197866

07

Vectored Immunoprophylaxis for Mucosal Immunity: Advances and Challenges Associated with Recombinant Secretory IgA Expression.

Manchester BJ, Gommerman JL, Sharif S, Susta L, Wootton SK

Vaccines2026

DOI: 10.3390/vaccines14080692 PMID: 42646709

08

Mapping of stakeholders in avian influenza surveillance in Canada.

Johncox E, Parmley EJ, Sharif S, Grant LE

One health outlook2025

DOI: 10.1186/s42522-025-00147-7 PMID: 40165335

09

Immune responses to avian influenza viruses in chickens.

Hassan MSH, Sharif S

Virology2025Senior author

DOI: 10.1016/j.virol.2025.110405 PMID: 39837219

10

Influenza a virus subtype H9N2 infection induces respiratory microbiota dysbiosis in chickens via type-I interferon-mediated mechanisms.

Oladokun S, Alizadeh M, Mallick AI, Fazel F, Doost JS, Blake K, Denis MS, Raj S, Sharif S

FEMS microbes2025Senior author

DOI: 10.1093/femsmc/xtaf001 PMID: 39991080

Canada Research Chairs Program Institutional Equity Stipend

Nominated PICIHR2025Chair: Canada Research Chairs Program Institutional Equity Stipend

Principal investigators: Sharif, Shayan

Keywords: Edi

$19,500

The Canadian One Health Training Program on Emerging Zoonoses

Co-investigatorCIHR2024Training Grant: HRTP - One Health - Emerging Zoonoses

Principal investigators: Parmley, Jane; Aenishaenslin, Cecile; Banerjee, Arinjay; Hillier, Sean A; Leighton, Patrick; Maguire, Finlay; Mubareka, Samira; Penney, Tarra L

Keywords: Emerging Zoonosis; Mentorship; One Health; Preparedness And Response; Prevention; Resilience; Sustainability; Training

$2,700,000

The H5Nx Genomic Landscape: Predictive Modelling of Host and Antigenic Transitions

Co-investigatorCIHR2024Catalyst Grant: Avian Influenza OneHealth Research

Principal investigators: Poljak, Zvonimir

Keywords: Antigenicity; Genomic Epidemiology; H5nx; Host; Machine Learning; Predictive Model; Risk Assessment; Surveillance

The H5Nx Genomic Landscape: Predictive Modelling of Host and Antigenic Transitions

Co-investigatorNSERC2024Alliance Grants

Principal investigators: Poljak, Zvonimir Z

$150,000

International Symposium on Avian Influenza

Co-investigatorCIHR2024Planning and Dissemination Grant - Institute Community Support

Principal investigators: Lang, Andrew S

Keywords: One Health; Pandemic Preparedness; Vaccines; Virology; Zoonotic Diseases

$20,000

Maintaining and Enhancing Flow Cytometry Capacity for Biological Research at the University of Guelph

Co-investigatorNSERC2023Research Tools and Instruments

Principal investigators: Wootton, Sarah

$150,000

A collaborative One Health approach to addressing highly pathogenic avian influenza virus, a clear and present danger

Co-investigatorCIHR2022Planning and Dissemination Grant - Institute Community Support

Principal investigators: Mubareka, Samira

Keywords: Biocontainment; Global Health And Security; Highly Pathogenic Avian Influenza Virus; One Health; Pandemic Preparedness

$25,000

High throughput real-time PCR instrument for studies of host responses to pathogens and cancer

Principal investigatorNSERC2021Research Tools and Instruments

Principal investigators: Sharif, Shayan

$74,797

Elucidating mechanisms of host-pathogen interactions in chickens

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Sharif, Shayan

$414,000

Is it possible to control avian influenza virus transmission?

Principal investigatorNSERC2018Collaborative Research and Development Grants

Principal investigators: Sharif, Shayan

$97,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Population Medicine
Pathobiology
Department of Laboratory Medicine and Pathobiology
Obstetrics & Gynecology
Molecular and Cellular Biology
Laboratory Medicine & Pathobiology
Medicine
Other

Co-authors at University of Guelph, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Zvonimir Poljak

Population Medicine

8 shared papers, latest 2023

Samira Mubareka

Department of Laboratory Medicine and Pathobiology

7 shared papers, latest 2026

Andrew Papadopoulos

Population Medicine

3 shared papers, latest 2023

James Petrik

Obstetrics & Gynecology

3 shared papers, latest 2018

Juliette Blais-Savoie

Laboratory Medicine & Pathobiology

1 shared papers, latest 2026

Patrick Boerlin

Pathobiology

1 shared papers, latest 2021

Anthony Clarke

Molecular and Cellular Biology

1 shared papers, latest 2008

Leonardo Susta

Pathobiology

1 shared papers, latest 2026

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Edi Dear Professor Sharif, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "A novel Bacillus subtilis strain alleviates necrotic enteritis in chickens by reducing NetB toxin from Clostridium perfringens." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Canada Research Chairs Program Institutional Equity Stipend" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Shayan Sharif

Research

Latest papers

Latest funding

A novel Bacillus subtilis strain alleviates necrotic enteritis in chickens by reducing NetB toxin from Clostridium perfringens.

Modulation of gut immunity and microbiota by Bacteroides thetaiotaomicron confers dose-dependent protection against necrotic enteritis in broiler chickens.

Transcriptomic profiling reveals early immune activation and metabolic remodeling in lymphoid tissues following in ovo Marek's disease virus mRNA vaccination in chickens.

Quantitative risk assessment of avian influenza: A scoping review.

Evaluating transient risk factors for avian influenza outbreaks in Canada using case-crossover study and machine learning.

Examining the Threat of H5N1 Highly Pathogenic Avian Influenza to Human Health.

Vectored Immunoprophylaxis for Mucosal Immunity: Advances and Challenges Associated with Recombinant Secretory IgA Expression.

Mapping of stakeholders in avian influenza surveillance in Canada.

Immune responses to avian influenza viruses in chickens.

Influenza a virus subtype H9N2 infection induces respiratory microbiota dysbiosis in chickens via type-I interferon-mediated mechanisms.

Canada Research Chairs Program Institutional Equity Stipend

The Canadian One Health Training Program on Emerging Zoonoses

The H5Nx Genomic Landscape: Predictive Modelling of Host and Antigenic Transitions

The H5Nx Genomic Landscape: Predictive Modelling of Host and Antigenic Transitions

International Symposium on Avian Influenza

Maintaining and Enhancing Flow Cytometry Capacity for Biological Research at the University of Guelph

A collaborative One Health approach to addressing highly pathogenic avian influenza virus, a clear and present danger

High throughput real-time PCR instrument for studies of host responses to pathogens and cancer

Elucidating mechanisms of host-pathogen interactions in chickens

Is it possible to control avian influenza virus transmission?

Frequent collaborators

John Parkinson

Zvonimir Poljak

Samira Mubareka

Andrew Papadopoulos

Byram Bridle

James Petrik

Juliette Blais-Savoie

Kevin Stinson

Patrick Boerlin

Anthony Clarke

Leonardo Susta