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Nongnuj Tanphaichitr

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Full ProfessorBiochemistry, Microbiology and ImmunologyUniversity of Ottawa

Nongnuj Tanphaichitr

Full Professor

Biochemistry, Microbiology and Immunology

Faculty of Medicine

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
4 publications in the last five years, latest in 2025.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 9 research grants (5 NSERC, 4 CIHR), most recently in 2020.
Supervisor on 1 trainee award (1 CIHR), most recently in 2009.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Read how they describe their research on their University of Ottawa profile.

Antimicrobial Peptide Hiv Ll-37 Vagina Contraceptive Microbicide Nanoparticle Neisseria Gonorrhoeae

Latest papers

A Short-Chain Analogue of Seminolipid: Synthesis and Inhibitory Effect on Mouse Fertilization.
Pharmaceuticals (Basel, Switzerland) · 2025 · senior author
Rats Orally Administered with Ethyl Alcohol for a Prolonged Time Show Histopathology of the Epididymis and Seminal Vesicle Together with Changes in the Luminal Metabolite Composition.
Biomedicines · 2024 · senior author
Safety of multiple administrations of spermicidal LL-37 antimicrobial peptide into the mouse female reproductive tract.
Molecular human reproduction · 2023 · senior author

All 29 publications

Latest funding

Use of antimicrobial peptides, LL-37/17BIPHE2, as vaginal spermicides/microbicides as part of multipurpose prevention technology (MPT)
CIHR · 2020 · Nominated PI
$734,400
Antimicrobial host defence peptides: their potential use as vaginal contraceptives with anti-HIV properties
CIHR · 2013 · Nominated PI
$622,391
""Sperm maturation and capacitation: Roles of Chaperone Proteins, Clusterin and Hsp70""
NSERC · 2012 · Principal investigator
$135,000

All 10 grants and awards

29 publications.

A Short-Chain Analogue of Seminolipid: Synthesis and Inhibitory Effect on Mouse Fertilization.

Lee SG, Vahdati L, Morelli L, Panza L, Compostella F, Tanphaichitr N

Pharmaceuticals (Basel, Switzerland)2025Senior author

DOI: 10.3390/ph18050611 PMID: 40430431

Rats Orally Administered with Ethyl Alcohol for a Prolonged Time Show Histopathology of the Epididymis and Seminal Vesicle Together with Changes in the Luminal Metabolite Composition.

Taoto C, Tangsrisakda N, Thukhammee W, Phetcharaburanin J, Iamsaard S, Tanphaichitr N

Biomedicines2024Senior author

DOI: 10.3390/biomedicines12051010 PMID: 38790972

Safety of multiple administrations of spermicidal LL-37 antimicrobial peptide into the mouse female reproductive tract.

Lee SG, Kiattiburut W, Burke Schinkel SC, Angel J, Tanphaichitr N

Molecular human reproduction2023Senior author

DOI: 10.1093/molehr/gaad023 PMID: 37326833

17BIPHE2, an engineered cathelicidin antimicrobial peptide with low susceptibility to proteases, is an effective spermicide and microbicide against Neisseria gonorrhoeae.

Lee SG, Kiattiburut W, Khongkha T, Schinkel SCB, Lunn Y, Decker AP, Mohammadi A, Vera-Cruz A, Misra A, Angel JB, Anderson DJ, Baker M, Kaul R, Wang G, Tanphaichitr N

Human reproduction (Oxford, England)2022Senior author

DOI: 10.1093/humrep/deac188 PMID: 36053257

Antimicrobial Peptide, LL-37, And Its Potential As An Anti-HIV Agent.

Vera-Cruz A, Tanphaichitr N, Angel JB

Clinical and investigative medicine. Medecine clinique et experimentale2021

DOI: 10.25011/cim.v44i3.36657 PMID: 34600462

Accumulation of Seminolipid in Sertoli Cells Is Associated with Increased Levels of Reactive Oxygen Species and Male Subfertility: Studies in Aging Arsa Null Male Mice.

Kongmanas K, Saewu A, Kiattiburut W, Baker MA, Faull KF, Burger D, Tanphaichitr N

Antioxidants (Basel, Switzerland)2021Senior author

DOI: 10.3390/antiox10060912 PMID: 34199863

Primary Sertoli Cell Cultures From Adult Mice Have Different Properties Compared With Those Derived From 20-Day-Old Animals.

Saewu A, Kongmanas K, Raghupathy R, Netherton J, Kadunganattil S, Linton JJ, Chaisuriyong W, Faull KF, Baker MA, Tanphaichitr N

Endocrinology2020Senior author

DOI: 10.1210/endocr/bqz020 PMID: 31730175

Sperm can act as vectors for HIV-1 transmission into vaginal and cervical epithelial cells.

Young CD, Tatieng S, Kongmanas K, Fongmoon D, Lomenick B, Yoon AJ, Kiattiburut W, Compostella F, Faull KF, Suree N, Angel JB, Tanphaichitr N

American journal of reproductive immunology (New York, N.Y. : 1989)2019Senior author

DOI: 10.1111/aji.13129 PMID: 31066971

Antimicrobial peptide LL-37 and its truncated forms, GI-20 and GF-17, exert spermicidal effects and microbicidal activity against Neisseria gonorrhoeae.

Kiattiburut W, Zhi R, Lee SG, Foo AC, Hickling DR, Keillor JW, Goto NK, Li W, Conlan W, Angel JB, Wang G, Tanphaichitr N

Human reproduction (Oxford, England)2018Senior author

DOI: 10.1093/humrep/dey315 PMID: 30357408

Properties, metabolism and roles of sulfogalactosylglycerolipid in male reproduction.

Tanphaichitr N, Kongmanas K, Faull KF, Whitelegge J, Compostella F, Goto-Inoue N, Linton JJ, Doyle B, Oko R, Xu H, Panza L, Saewu A

Progress in lipid research2018First author

DOI: 10.1016/j.plipres.2018.08.002 PMID: 30149090

Use of antimicrobial peptides, LL-37/17BIPHE2, as vaginal spermicides/microbicides as part of multipurpose prevention technology (MPT)

Nominated PICIHR2020Project Grant

Principal investigators: Tanphaichitr, Nongnuj; Angel, Jonathan B; Gadde, Suresh; Sheth, Prameet M

Keywords: Antimicrobial Peptide; Contraceptive; Hiv; Ll-37; Microbicide; Nanoparticle; Neisseria Gonorrhoeae; Spermicide; Vagina; Vaginal Microbiome

$734,400

Antimicrobial host defence peptides: their potential use as vaginal contraceptives with anti-HIV properties

Nominated PICIHR2013Operating Grant

Principal investigators: Tanphaichitr, Nongnuj; Angel, Jonathan B

Keywords: Antimicrobial Peptide; Cervix; Fertilization; Hiv; Ll-37; Non-Hormonal Contraceptive; Sperm Functions; Sperm Membranes; Vagina; Vaginal Contraceptive

$622,391

""Sperm maturation and capacitation: Roles of Chaperone Proteins, Clusterin and Hsp70""

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Tanphaichitr, Nongnuj

$135,000

Seminolipid homeostasis: its significance in male reproduction

Nominated PICIHR2011Operating Grant

Principal investigators: Tanphaichitr, Nongnuj

Keywords: Arylsulfatase; Electrospray Ionization Mass Spectrometry; Glycolipid; Lysosome Storage Disorder; Male Fertility; Seminoplid; Sertoli Cells; Sperm; Spermatogenesis; Testicular Germ Cells

$519,224

Roles of seminolipid and its binding proteins in male reproduction

Principal investigatorNSERC2010Discovery Grants Program - Individual

Principal investigators: Tanphaichitr, Nongnuj

$30,000

Role of sulfogalactosylglycerolipid as an egg binding molecule

SupervisorCIHR2009Master's Award: Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Sugeng, Clarissa K

Keywords: Apical/Anterior Sperm Head Plasma Membrane; Fertilization; Lipid Rafts; Male Reproduction; Protein-Lipid Interaction; Sulfogalactosylglycerolipid (Sgg); Sulfoglycolipid; Zona Pellucida

$17,500

CIHR Training Program in Reproduction, Early Development, and the Impact on Health (REDIH)

Principal investigatorCIHR2008Training Grant

Principal investigators: Baltz, Jay M; Clarke, Hugh J; Dufort, Daniel; Foster, Warren G; Gibb, William; Gruslin, Andree M; Hales, Barbara F; Kidder, Gerald M; Leader, Arthur; Leveille, Marie-Claude; Liu, Johne X; Macdonald, Colla J; Mann, Mellissa; McDonald, Sarah D; Murphy, Bruce D; Nisker, Jeffrey A; Richard, François; Robaire, Bernard; Sirard, Marc-André; Smith, Lawrence C; Tanphaichitr, Nongnuj; Trasler, Jacquetta M; Tsang, Benjamin K; Vanderhyden, Barbara C; Wade, Michael G; Walker, Mark C; Watson, Andrew J; Wen, Shi Wu; Yang, Kaiping; Yang, Qiuying

Keywords: Development; Ethics; Maternal Fetal Health; Origins Of Disease; Reproduction; Training

$1,787,598

Capacitated sperm rafts as platforms of ZP binding and signaling molecules.

Principal investigatorNSERC2004Discovery Grants Program - Individual

Principal investigators: Tanphaichitr, Nongnuj

$199,500

Characterization and role of mammalian sperm lipids on sperm functions

Principal investigatorNSERC2000Discovery Grants Program - Individual

Principal investigators: Tanphaichitr, Nongnuj

$106,000

Roles of sperm and epididymal lipids on mammalian sperm maturation and capacitation

Principal investigatorNSERC1996Discovery Grants Program - Individual

Principal investigators: Tanphaichitr, Nongnuj

$102,120

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Nongnuj Tanphaichitr

Research

Latest papers

Latest funding

A Short-Chain Analogue of Seminolipid: Synthesis and Inhibitory Effect on Mouse Fertilization.

Rats Orally Administered with Ethyl Alcohol for a Prolonged Time Show Histopathology of the Epididymis and Seminal Vesicle Together with Changes in the Luminal Metabolite Composition.

Safety of multiple administrations of spermicidal LL-37 antimicrobial peptide into the mouse female reproductive tract.

17BIPHE2, an engineered cathelicidin antimicrobial peptide with low susceptibility to proteases, is an effective spermicide and microbicide against Neisseria gonorrhoeae.

Antimicrobial Peptide, LL-37, And Its Potential As An Anti-HIV Agent.

Accumulation of Seminolipid in Sertoli Cells Is Associated with Increased Levels of Reactive Oxygen Species and Male Subfertility: Studies in Aging Arsa Null Male Mice.

Primary Sertoli Cell Cultures From Adult Mice Have Different Properties Compared With Those Derived From 20-Day-Old Animals.

Sperm can act as vectors for HIV-1 transmission into vaginal and cervical epithelial cells.

Antimicrobial peptide LL-37 and its truncated forms, GI-20 and GF-17, exert spermicidal effects and microbicidal activity against Neisseria gonorrhoeae.

Properties, metabolism and roles of sulfogalactosylglycerolipid in male reproduction.

Use of antimicrobial peptides, LL-37/17BIPHE2, as vaginal spermicides/microbicides as part of multipurpose prevention technology (MPT)

Antimicrobial host defence peptides: their potential use as vaginal contraceptives with anti-HIV properties

""Sperm maturation and capacitation: Roles of Chaperone Proteins, Clusterin and Hsp70""

Seminolipid homeostasis: its significance in male reproduction

Roles of seminolipid and its binding proteins in male reproduction

Role of sulfogalactosylglycerolipid as an egg binding molecule

CIHR Training Program in Reproduction, Early Development, and the Impact on Health (REDIH)

Capacitated sperm rafts as platforms of ZP binding and signaling molecules.

Characterization and role of mammalian sperm lipids on sperm functions

Roles of sperm and epididymal lipids on mammalian sperm maturation and capacitation

Frequent collaborators

Jason Fernandes

Dylan Burger

Ajoy Basak

Jonathan Angel

Richard Oko

Rupert Kaul