Jonathan Angel, University of Ottawa

Research

Read how they describe their research on their University of Ottawa profile.

Hiv Knowledge Dissemination Vaccines Knowledge Translation Education Continuing Education Vaccine Career Preparation

Latest papers

Safety of multiple administrations of spermicidal LL-37 antimicrobial peptide into the mouse female reproductive tract.
Molecular human reproduction · 2023
Virological Outcomes After Switching to Abacavir/Lamivudine/Dolutegravir Combined with Adherence Support in People Living with HIV with Poor Adherence: A Phase IV, Multicentre Randomized Prospective Open Label Study (TriiADD-CTN 286).
Patient preference and adherence · 2022
Repurposing Metformin in Nondiabetic People With HIV: Influence on Weight and Gut Microbiota.
Open forum infectious diseases · 2020

All 6 publications

Latest funding

HIV Vaccines: Search for a Cure
CIHR · 2024 · Nominated PI
$20,000
Reality Check: HIV Vaccine Failures, Progress and the Way Forward
CIHR · 2023 · Nominated PI
$20,000
HIV Vaccines: Taking Stock
CIHR · 2022 · Nominated PI
$15,000

All 39 grants and awards

6 publications.

01

Safety of multiple administrations of spermicidal LL-37 antimicrobial peptide into the mouse female reproductive tract.

Lee SG, Kiattiburut W, Burke Schinkel SC, Angel J, Tanphaichitr N

Molecular human reproduction2023

DOI: 10.1093/molehr/gaad023 PMID: 37326833

02

Virological Outcomes After Switching to Abacavir/Lamivudine/Dolutegravir Combined with Adherence Support in People Living with HIV with Poor Adherence: A Phase IV, Multicentre Randomized Prospective Open Label Study (TriiADD-CTN 286).

Klein MB, Young J, Ortiz-Paredes D, Wang S, Walmsley S, Wong A, Martel-Laferrière V, Pick N, Conway B, Angel J, Baril JG, Fraser C, Lebouché B, Tan DHS, Sandre R, Trottier S, Peiris H, Jayaraman J, Singer J, CTN 286 Study Investigators

Patient preference and adherence2022

DOI: 10.2147/ppa.s379065 PMID: 36536672

03

Repurposing Metformin in Nondiabetic People With HIV: Influence on Weight and Gut Microbiota.

Isnard S, Lin J, Fombuena B, Ouyang J, Varin TV, Richard C, Marette A, Ramendra R, Planas D, Raymond Marchand L, Messaoudene M, Van der Ley CP, Kema IP, Sohail Ahmed D, Zhang Y, Finkelman M, Routy B, Angel J, Ancuta P, Routy JP

Open forum infectious diseases2020

DOI: 10.1093/ofid/ofaa338 PMID: 32964062

04

cIAP1/2-TRAF2-SHP-1-Src-MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through NF-κB Activation in Human Macrophages.

Busca A, Konarski Y, Gajanayaka N, O'Hara S, Angel J, Kozlowski M, Kumar A

Journal of immunology (Baltimore, Md. : 1950)2018

DOI: 10.4049/jimmunol.1700199 PMID: 29358273

05

An HIV-tailored quit-smoking counselling pilot intervention targeting depressive symptoms plus Nicotine Replacement Therapy.

Balfour L, Wiebe SA, Cameron WD, Sandre D, Pipe A, Cooper C, Angel J, Garber G, Holly C, Dalgleish TL, Tasca GA, MacPherson PA

AIDS care2017

DOI: 10.1080/09540121.2016.1201195 PMID: 27435835

06

PI3K/Akt regulates survival during differentiation of human macrophages by maintaining NF-κB-dependent expression of antiapoptotic Bcl-xL.

Busca A, Saxena M, Iqbal S, Angel J, Kumar A

Journal of leukocyte biology2014

DOI: 10.1189/jlb.1a0414-212r PMID: 25225677

HIV Vaccines: Search for a Cure

Nominated PICIHR2024Planning and Dissemination Grant - Institute Community Support

Principal investigators: Angel, Jonathan B

Keywords: Hiv; Knowledge Dissemination; Vaccine; Virology

$20,000

Reality Check: HIV Vaccine Failures, Progress and the Way Forward

Nominated PICIHR2023Planning and Dissemination Grant - Institute Community Support

Principal investigators: Angel, Jonathan B

Keywords: Hiv; Vaccines; Virology

$20,000

HIV Vaccines: Taking Stock

Nominated PICIHR2022Planning and Dissemination Grant - Institute Community Support

Principal investigators: Angel, Jonathan B

Keywords: Hiv; Vaccines

$15,000

COVID-19 Variant Supplement - Development of Vaccines to Prevent SARS-CoV-2 Infection of High Risk Individuals

Co-investigatorCIHR2021Operating Grant: SARS-CoV-2 variants supplement stream 1

Principal investigators: Bell, John C; Ilkow, Carolina S; Lapointe, Réjean; Mahoney, Douglas J

Keywords: Covid-19; Epitopes; Immunity; Infection; Manufacturing; Pre-Clinical; Sars-Cov-2; Vaccine

$50,000

A Pilot Feasibility Study to Inform the Development of a Novel Clinical and Biomarker-driven Definition of COPD Exacerbation among Hospitalized Adults in Canada

Co-investigatorCIHR2021Catalyst Grant: Breathing as One - Boehringer Ingelheim Canada COPD Grant

Principal investigators: Mulpuru, Sunita

Keywords: Biomarkers; Copd; Exacerbations; Feasibility Study

$15,000

Use of antimicrobial peptides, LL-37/17BIPHE2, as vaginal spermicides/microbicides as part of multipurpose prevention technology (MPT)

Principal investigatorCIHR2020Project Grant

Principal investigators: Tanphaichitr, Nongnuj; Angel, Jonathan B; Gadde, Suresh; Sheth, Prameet M

Keywords: Antimicrobial Peptide; Contraceptive; Hiv; Ll-37; Microbicide; Nanoparticle; Neisseria Gonorrhoeae; Spermicide; Vagina; Vaginal Microbiome

$734,400

Development of Vaccines to Prevent SARS-CoV-2 Infection of High Risk Individuals

Co-investigatorCIHR2020Operating Grant: COVID-19 Rapid Research Funding Opportunity - Vaccines

Principal investigators: Bell, John C; Ilkow, Carolina S; Lapointe, Réjean; Mahoney, Douglas J

Keywords: Covid-19; Epitopes; Immunity; Infection; Manufacturing; Pre-Clinical; Sars-Cov-2; Vaccine

$1,936,150

HIV Vaccines: Progress, Failures and New Directions

Nominated PICIHR2018Planning and Dissemination Grant - Institute Community Support

Principal investigators: Angel, Jonathan B; Grant, Michael D

Keywords: Health Research; Hiv; Knowledge Translation; Vaccine

$19,000

HIV Vaccines: Where do we go next?

Nominated PICIHR2017Planning and Dissemination Grant - Institute Community Support

Principal investigators: Angel, Jonathan B

Keywords: Health Research; Hiv; Knowledge Translation; Vaccine

$20,000

The Road Ahead: HIV Vaccines

Nominated PICIHR2016Planning and Dissemination Grant - Institute Community Support

Principal investigators: Angel, Jonathan B; Grant, Michael D

Keywords: Education; Hiv; Knowledge Dissemination; Vaccines

$15,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biochemistry, Microbiology and Immunology
Pathology and Laboratory Medicine
Department of Medicine
Family Medicine
Hematology-Oncology
Microbiology and Immunology
Medicine
Other

Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Ashok Kumar

Pathology and Laboratory Medicine

2 shared papers, latest 2018

Curtis Cooper

Department of Medicine

1 shared papers, latest 2017

Jean-Pierre Routy

Medicine

1 shared papers, latest 2020

Jean-Pierre Routy

Microbiology and Immunology

1 shared papers, latest 2020

Nongnuj Tanphaichitr

Biochemistry, Microbiology and Immunology

1 shared papers, latest 2023

Sharon Walmsley

School of Population and Public Health

1 shared papers, latest 2022

Sharon Walmsley

Infectious Diseases

1 shared papers, latest 2022

Bertrand Routy

Hematology-Oncology

1 shared papers, latest 2020

Andrew Pipe

Family Medicine

1 shared papers, latest 2017

Neora Pick

Pathology and Laboratory Medicine

1 shared papers, latest 2022

Gary Garber

Department of Medicine

1 shared papers, latest 2017

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2024

Subject: Prospective PhD student: Hiv Dear Professor Angel, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Safety of multiple administrations of spermicidal LL-37 antimicrobial peptide into the mouse female reproductive tract." (2023), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "HIV Vaccines: Search for a Cure" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Jonathan Angel

Research

Latest papers

Latest funding

Safety of multiple administrations of spermicidal LL-37 antimicrobial peptide into the mouse female reproductive tract.

Virological Outcomes After Switching to Abacavir/Lamivudine/Dolutegravir Combined with Adherence Support in People Living with HIV with Poor Adherence: A Phase IV, Multicentre Randomized Prospective Open Label Study (TriiADD-CTN 286).

Repurposing Metformin in Nondiabetic People With HIV: Influence on Weight and Gut Microbiota.

cIAP1/2-TRAF2-SHP-1-Src-MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through NF-&#x3ba;B Activation in Human Macrophages.

An HIV-tailored quit-smoking counselling pilot intervention targeting depressive symptoms plus Nicotine Replacement Therapy.

PI3K/Akt regulates survival during differentiation of human macrophages by maintaining NF-&#x3ba;B-dependent expression of antiapoptotic Bcl-xL.

Frequent collaborators

Ashok Kumar

Curtis Cooper

Jean-Pierre Routy

Jean-Pierre Routy

Nongnuj Tanphaichitr

Sharon Walmsley

Sharon Walmsley

Bertrand Routy

Andrew Pipe

Neora Pick

Gary Garber

cIAP1/2-TRAF2-SHP-1-Src-MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through NF-κB Activation in Human Macrophages.

PI3K/Akt regulates survival during differentiation of human macrophages by maintaining NF-κB-dependent expression of antiapoptotic Bcl-xL.