Faculty profile

Anthony Fyles

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Professor EmeritusDepartment of Radiation OncologyUniversity of Toronto

Anthony Fyles

Professor Emeritus

Department of Radiation Oncology

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Emeritus professors are retired and rarely take new students.
11 publications in the last five years, latest in 2026.
Principal investigator on 1 research grant (1 CIHR), most recently in 2011.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

3,433

Citations

127

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Clinical Outcomes and Institutional Experience of Ultrahypofractionated Radiation Therapy in Patients With Breast Cancer.
Advances in radiation oncology · 2026
Geometrically focused training and evaluation of organs-at-risk segmentation via deep learning.
Medical physics · 2025
Validation of a breast cancer assay for radiotherapy omission: an individual participant data meta-analysis.
Journal of the National Cancer Institute · 2025

All 69 publications

Latest funding

Tailored adjuvant therapy in POLE-mutated and p53-wildtype early stage endometrial cancer (TAPER)
CIHR · 2020 · Co-investigator
$1,082,474
A Randomized Trial of Regional Radiotherapy in Luminal A Breast Cancer
CIHR · 2016 · Co-investigator
$4,923,383
Canadian Accelerated Partial Breast Irradiation
CIHR · 2011 · Co-investigator
$899,947

All 6 grants and awards

69 publications.

Clinical Outcomes and Institutional Experience of Ultrahypofractionated Radiation Therapy in Patients With Breast Cancer.

Othman H, Barry A, Fyles A, Rodin D, Hahn E, Liu FF, Helou J, Han K, Glicksman R, Isfahanian N, Baskurt Z, Chan M, Purdie T, Koch A, Croke J

Advances in radiation oncology2026Open Access

DOI: 10.1016/j.adro.2025.101948 PMID: 41541755

Geometrically focused training and evaluation of organs-at-risk segmentation via deep learning.

Ni R, Chuk E, Han K, Croke J, Fyles A, Lukovic J, Milosevic M, Haibe-Kains B, Rink A

Medical physics20254 citationsOpen Access

DOI: 10.1002/mp.17840 PMID: 40280876

Validation of a breast cancer assay for radiotherapy omission: an individual participant data meta-analysis.

Karlsson P, Fyles A, Chang SL, Arrick B, Baehner FL, Malmström P, Fernö M, Holmberg E, Sjöström M, Liu FF, Cameron DA, Williams LJ, Bartlett JMS, Dunlop J, Caldwell J, Loane JF, Mallon E, Piper T, Kunkler I, Feng FY, Speers CW, Pierce LJ, Bennett JP, Taylor KJ

Journal of the National Cancer Institute20254 citationsOpen Access

DOI: 10.1093/jnci/djae262 PMID: 39423142

Intra-operative process efficiency for in-room MRI-guided combined intracavitary/interstitial brachytherapy for cervical cancer.

Chan K, Ballantyne H, Liu ZA, Milosevic M, Croke J, Fyles A, Lukovic J, Rink A, Beiki-Ardakani A, Borg J, Serban M, Weersink RA, Conway JL, Rauth S, Skliarenko J, Xie J, Simeonov A, Han K

Brachytherapy2025Open Access

DOI: 10.1016/j.brachy.2025.07.001 PMID: 40750473

Response to Li, Liu, Duan, et al.

Karlsson P, Fyles A, Arrick B, Holmberg E, Sjöström M, Cameron DA, Williams LJ, Kunkler I, Speers CW, Pierce LJ, Bennett JP, Taylor KJ

Journal of the National Cancer Institute2025

DOI: 10.1093/jnci/djaf116 PMID: 40331581

Clinical Validation of Human Papilloma Virus Circulating Tumor DNA for Early Detection of Residual Disease After Chemoradiation in Cervical Cancer.

Han K, Zou J, Zhao Z, Baskurt Z, Zheng Y, Barnes E, Croke J, Ferguson SE, Fyles A, Gien L, Gladwish A, Lecavalier-Barsoum M, Lheureux S, Lukovic J, Mackay H, Marchand EL, Metser U, Milosevic M, Taggar AS, Bratman SV, Leung E

Journal of clinical oncology : official journal of the American Society of Clinical Oncology202474 citationsOpen Access

DOI: 10.1200/jco.23.00954 PMID: 37972346

Clinical Outcomes of 3 Versus 4 Fractions of Magnetic Resonance Image-Guided Brachytherapy in Cervical Cancer.

Chuk E, Yu C, Scott AA, Liu ZA, Milosevic M, Croke J, Fyles A, Lukovic J, Rink A, Beiki-Ardakani A, Borg J, Skliarenko J, Conway JL, Weersink RA, Han K

International journal of radiation oncology, biology, physics202412 citationsOpen Access

DOI: 10.1016/j.ijrobp.2024.06.011 PMID: 38936633

LUMINA: Using molecular biomarkers to guide decision making for breast radiotherapy

Whelan TJ, Fyles A, Parpia S, Nielsen T, Levine MN

Radiotherapy and Oncology20245 citations

DOI: 10.1016/j.radonc.2023.110074

Development and Validation of a Genomic Profile for the Omission of Local Adjuvant Radiation in Breast Cancer.

Sjöström M, Fyles A, Liu FF, McCready D, Shi W, Rey-McIntyre K, Chang SL, Feng FY, Speers CW, Pierce LJ, Holmberg E, Fernö M, Malmström P, Karlsson P

Journal of clinical oncology : official journal of the American Society of Clinical Oncology202363 citationsOpen Access

DOI: 10.1200/jco.22.00655 PMID: 36599119

Reply to V. Nardone et al.

Sjöström M, Fyles A, Liu FF, McCready D, Feng FY, Speers CW, Pierce LJ, Holmberg E, Fernö M, Malmström P, Karlsson P

Journal of clinical oncology : official journal of the American Society of Clinical Oncology2023

DOI: 10.1200/jco.23.00566 PMID: 37279434

Tailored adjuvant therapy in POLE-mutated and p53-wildtype early stage endometrial cancer (TAPER)

Co-investigatorCIHR2020Project Grant

Principal investigators: Han, Kathy; Mcalpine, Jessica N

Keywords: Clinical Trial; De-Escalation Therapy; Decisional Conflict; Endometrial Cancer; Molecular Biomarker; P53/Tp53; Personalized Cancer Treatment; Pole; Quality Of Life; Translational Research

$1,082,474

A Randomized Trial of Regional Radiotherapy in Luminal A Breast Cancer

Co-investigatorCIHR2016Project Grant

Principal investigators: Whelan, Timothy J

Keywords: Biomarkers; Breast Cancer; Radiation Therapy

$4,923,383

Canadian Accelerated Partial Breast Irradiation

Co-investigatorCIHR2011Operating Grant

Principal investigators: Whelan, Timothy J; Olivotto, Ivo A

Keywords: Accelerated Partial Breast Irradiation; Breast Cancer; Radiation Therapy; Randomized Trial

$899,947

Avoidance of Radiotherapy in Luminal A Breast Cancer

Principal investigatorCIHR2011Operating Grant

Principal investigators: Whelan, Timothy J; Fyles, Anthony W; Liu, Fei-Fei

Keywords: Breast Cancer; Cohort Study; Instrinsic Subtypes; Radiotherapy

$339,130

MicroRNA and mRNA Expression Profiling to Predict Outcome and Characterize the Cervix Cancer Microenvironment

Co-investigatorCIHR2010Operating Grant - PA: Cancer Research (bridge funding)

Principal investigators: Liu, Fei-Fei

Keywords: Cervix Cancer; Microrna; Mrna Profiling; Predictor Of Radiosensitivity; Prognostic Marker; Radiation Treatment

$100,000

The Terry Fox Foundation Strategic Training Initiative for Excellence in Radiation Research for the 21st Century (EIRR21) at CIHR

Co-investigatorCIHR2008Terry Fox Foundation Training Grant in Cancer Research at CIHR -Full application

Principal investigators: Liu, Fei-Fei

Keywords: Capacity Building; Innovation; Leadership Skills; Radiation Research; Trans-Disciplinarity

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Anthony Fyles

Research

Latest papers

Latest funding

Clinical Outcomes and Institutional Experience of Ultrahypofractionated Radiation Therapy in Patients With Breast Cancer.

Geometrically focused training and evaluation of organs-at-risk segmentation via deep learning.

Validation of a breast cancer assay for radiotherapy omission: an individual participant data meta-analysis.

Intra-operative process efficiency for in-room MRI-guided combined intracavitary/interstitial brachytherapy for cervical cancer.

Response to Li, Liu, Duan, et al.

Clinical Validation of Human Papilloma Virus Circulating Tumor DNA for Early Detection of Residual Disease After Chemoradiation in Cervical Cancer.

Clinical Outcomes of 3 Versus 4 Fractions of Magnetic Resonance Image-Guided Brachytherapy in Cervical Cancer.

LUMINA: Using molecular biomarkers to guide decision making for breast radiotherapy

Development and Validation of a Genomic Profile for the Omission of Local Adjuvant Radiation in Breast Cancer.

Reply to V. Nardone et al.

Tailored adjuvant therapy in POLE-mutated and p53-wildtype early stage endometrial cancer (TAPER)

A Randomized Trial of Regional Radiotherapy in Luminal A Breast Cancer

Canadian Accelerated Partial Breast Irradiation

Avoidance of Radiotherapy in Luminal A Breast Cancer

MicroRNA and mRNA Expression Profiling to Predict Outcome and Characterize the Cervix Cancer Microenvironment

The Terry Fox Foundation Strategic Training Initiative for Excellence in Radiation Research for the 21st Century (EIRR21) at CIHR

Frequent collaborators

Michael Milosevic

Kathy Han

Jennifer Croke

Fei-Fei Liu

Ur Metser

Jelena Lukovic

Eric Leung

Alexandra Rink

David Jaffray

Amit Oza

Laurie Elit

Ivan Yeung

Thomas Purdie

Gillian Thomas

Julia Skliarenko

David McCready

Anna Simeonov

Ezra Hahn

Rinku Sutradhar

Eileen Rakovitch

Timothy Whelan

David Hedley

Mark Norman Levine

Elizabeth Barnes

Nicole Harnett

Rachel Glicksman

Adam Gladwish

Harald Keller

Valerie Kelly

Anne Koch

Helen MacKay

Amandeep Taggar

Grace Lee

Allan Covens

Eitan Amir

Iwa Kong

André-Guy Martin

Dana Keilty

Padraig Warde

Patricia Lindsay