Faculty profile

David Jaffray

ResearcherPharmaceutical SciencesUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

David Jaffray

Researcher

Pharmaceutical Sciences

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
3 publications in the last five years, latest in 2024.
Principal investigator on 10 research grants (7 CIHR, 3 NSERC), most recently in 2019.
Supervised 2 trainees who won CIHR awards, most recently in 2014.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Radiation Therapy Hyperthermia Breast Cancer Nanotechnology Chest Wall Recurrence Drug Delivery Image-Guided Drug Delivery Thermosensitive Liposomes

Latest papers

On dosimetric characteristics of detectors for relative dosimetry in small fields: a multicenter experimental study.
Physics in medicine and biology · 2024
A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
Phantom Validation of a Conservation of Activity-Based Partial Volume Correction Method for Arterial Input Function in Dynamic PET Imaging.
Tomography (Ann Arbor, Mich.) · 2022

All 59 publications

Latest funding

Advanced CT Strategies for Image Quality Improvement and Dose Reduction
NSERC · 2019 · Principal investigator
$71,500
Genomics-based radiosensitization for HPV-negative squamous cell carcinoma of the aerodigestive tract
CIHR · 2018 · Co-investigator
$757,352
Heat Activated Liposomal Delivery of Chemo and Molecular Therapy in Combination with Radiotherapy for Treatment of Breast Cancer Recurrence at the Chest Wall
CIHR · 2017 · Principal investigator
$459,000

All 24 grants and awards

59 publications.

On dosimetric characteristics of detectors for relative dosimetry in small fields: a multicenter experimental study.

Casar B, Mendez I, Gershkevitsh E, Wegener S, Jaffray D, Heaton R, Pesznyak C, Stelczer G, Bulski W, Chełminski K, Smirnov G, Antipina N, Beavis AW, Harding N, Jurković S, Hwang MS, Saiful Huq M

Physics in medicine and biology2024

DOI: 10.1088/1361-6560/ad154c PMID: 38091616

A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer.

Han K, Fyles A, Shek T, Croke J, Dhani N, D'Souza D, Lee TY, Chaudary N, Bruce J, Pintilie M, Cairns R, Vines D, Pakbaz S, Jaffray D, Metser U, Rouzbahman M, Milosevic M, Koritzinsky M

Clinical cancer research : an official journal of the American Association for Cancer Research2022

DOI: 10.1158/1078-0432.ccr-22-1665 PMID: 36037303

Phantom Validation of a Conservation of Activity-Based Partial Volume Correction Method for Arterial Input Function in Dynamic PET Imaging.

Driscoll B, Shek T, Vines D, Sun A, Jaffray D, Yeung I

Tomography (Ann Arbor, Mich.)2022

DOI: 10.3390/tomography8020069 PMID: 35314646

4D-CT Attenuation Correction in Respiratory-Gated PET for Hypoxia Imaging: Is It Really Beneficial?

Driscoll B, Vines D, Shek T, Publicover J, Yeung I, Breen S, Jaffray D

Tomography (Ann Arbor, Mich.)2020Senior author

DOI: 10.18383/j.tom.2019.00027 PMID: 32548302

Artificial intelligence-based clinical decision support in modern medical physics: Selection, acceptance, commissioning, and quality assurance.

Mahadevaiah G, Rv P, Bermejo I, Jaffray D, Dekker A, Wee L

Medical physics2020

DOI: 10.1002/mp.13562 PMID: 32418341

An artificial neural network to model response of a radiotherapy beam monitoring system.

Cho YB, Farrokhkish M, Norrlinger B, Heaton R, Jaffray D, Islam M

Medical physics2020

DOI: 10.1002/mp.14033 PMID: 31955428

Machine learning helps identifying volume-confounding effects in radiomics.

Traverso A, Kazmierski M, Zhovannik I, Welch M, Wee L, Jaffray D, Dekker A, Hope A

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)2020

DOI: 10.1016/j.ejmp.2020.02.010 PMID: 32088562

Sensitivity of radiomic features to inter-observer variability and image pre-processing in Apparent Diffusion Coefficient (ADC) maps of cervix cancer patients.

Traverso A, Kazmierski M, Welch ML, Weiss J, Fiset S, Foltz WD, Gladwish A, Dekker A, Jaffray D, Wee L, Han K

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology2020

DOI: 10.1016/j.radonc.2019.08.008 PMID: 31477335

Repeatability and reproducibility of MRI-based radiomic features in cervical cancer.

Fiset S, Welch ML, Weiss J, Pintilie M, Conway JL, Milosevic M, Fyles A, Traverso A, Jaffray D, Metser U, Xie J, Han K

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology2019

DOI: 10.1016/j.radonc.2019.03.001 PMID: 31015155

Stability of radiomic features of apparent diffusion coefficient (ADC) maps for locally advanced rectal cancer in response to image pre-processing.

Traverso A, Kazmierski M, Shi Z, Kalendralis P, Welch M, Nissen HD, Jaffray D, Dekker A, Wee L

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)2019

DOI: 10.1016/j.ejmp.2019.04.009 PMID: 31151578

Advanced CT Strategies for Image Quality Improvement and Dose Reduction

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Jaffray, David

$71,500

Genomics-based radiosensitization for HPV-negative squamous cell carcinoma of the aerodigestive tract

Co-investigatorCIHR2018Project Grant

Principal investigators: Bratman, Scott V; Ailles, Laurie E; Haibe-Kains, Benjamin

Keywords: Cdk4/6 Inhibitors; Chemoradiation; Nrf2 Pathway; Personalized Cancer Medicine; Pharmacogenomics; Preclinical Research; Radiogenomics; Radiotherapy; Squamous Cell Carcinoma; Therapeutic Index

$757,352

Heat Activated Liposomal Delivery of Chemo and Molecular Therapy in Combination with Radiotherapy for Treatment of Breast Cancer Recurrence at the Chest Wall

Principal investigatorCIHR2017Project Grant

Principal investigators: Allen, Christine J; Jaffray, David A

Keywords: Breast Cancer; Chest Wall Recurrence; Drug Delivery; Hyperthermia; Image-Guided Drug Delivery; Radiation Therapy; Thermosensitive Liposomes

$459,000

Spatially encoded mass spectrometry data for intrasurgical pathology

Principal investigatorNSERC2017Engage Grants Program

Principal investigators: Jaffray, David

$25,000

Integrated Image-Guidance Platform for High-Precision Cancer Surgery

Co-investigatorCIHR2016Project Grant

Principal investigators: Zheng, Jinzi

Keywords: Cancer; Cancer Surgery; Contrast Agent; Image-Guidance; Intraoperative Imaging; Nanotechnology

$100,000

Clinical Investigation of Frameless, Adaptive, Image-guided Gamma Knife Radiosurgery

Co-investigatorCIHR2015Operating Grant: Industry-partnered Collaborative Research

Principal investigators: Chung, Caroline

Keywords: Adaptive Treatment; Brain Tumor; Cancer; Image-Guided; Metastases; Palliation; Personalized Medicine; Radiation; Radiosurgery; Real-Time Monitoring

$264,656

Improving Target Definition in Radiation Therapy Planning by the Spatial Registration of Optical Endoscopy Imaging with Volumetric Imaging

Co-investigatorCIHR2015Operating Grant

Principal investigators: Weersink, Robert A

Keywords: Endoscopy; Image Guidance; Image Registration; Radiation Therapy

$280,582

Magnetic Resonance Imaging-Guided Radiotherapy for Cervix Cancer Response Monitoring and Treatment Adaptation

SupervisorCIHR2014CIHR Fellowship

Principal investigators: Velec, Michael

Keywords: Adaptive Radiation Therapy; Biomechanical Models; Deformable Image Registration; Dose Accumulation; Gynecologic Cancers; Magnetic Resonance Imaging (Mri)

$165,000

Advanced Strategies for Image Quality Improvement and Dose Reduction in CT

Principal investigatorNSERC2014Discovery Grants Program - Individual

Principal investigators: Jaffray, David

$180,000

Image-based quantitative assessment of tumor hypoxia

Nominated PICIHR2014Operating Grant: Quantitative Imaging for Responses to Cancer Therapies

Principal investigators: Jaffray, David A; Coolens, Catherine; Dhani, Neesha C; Hedley, David W; Joshua, Anthony; Lee, Ting-Yim; Milosevic, Michael; Palma, David; Valliant, John F; Wouters, Bradly; Yeung, Ivan Wai Tong

Keywords: Quantitative Assessment

$1,923,621

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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David Jaffray

Research

Latest papers

Latest funding

On dosimetric characteristics of detectors for relative dosimetry in small fields: a multicenter experimental study.

A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer.

Phantom Validation of a Conservation of Activity-Based Partial Volume Correction Method for Arterial Input Function in Dynamic PET Imaging.

4D-CT Attenuation Correction in Respiratory-Gated PET for Hypoxia Imaging: Is It Really Beneficial?

Artificial intelligence-based clinical decision support in modern medical physics: Selection, acceptance, commissioning, and quality assurance.

An artificial neural network to model response of a radiotherapy beam monitoring system.

Machine learning helps identifying volume-confounding effects in radiomics.

Sensitivity of radiomic features to inter-observer variability and image pre-processing in Apparent Diffusion Coefficient (ADC) maps of cervix cancer patients.

Repeatability and reproducibility of MRI-based radiomic features in cervical cancer.

Stability of radiomic features of apparent diffusion coefficient (ADC) maps for locally advanced rectal cancer in response to image pre-processing.

Advanced CT Strategies for Image Quality Improvement and Dose Reduction

Genomics-based radiosensitization for HPV-negative squamous cell carcinoma of the aerodigestive tract

Heat Activated Liposomal Delivery of Chemo and Molecular Therapy in Combination with Radiotherapy for Treatment of Breast Cancer Recurrence at the Chest Wall

Spatially encoded mass spectrometry data for intrasurgical pathology

Integrated Image-Guidance Platform for High-Precision Cancer Surgery

Clinical Investigation of Frameless, Adaptive, Image-guided Gamma Knife Radiosurgery

Improving Target Definition in Radiation Therapy Planning by the Spatial Registration of Optical Endoscopy Imaging with Volumetric Imaging

Magnetic Resonance Imaging-Guided Radiotherapy for Cervix Cancer Response Monitoring and Treatment Adaptation

Advanced Strategies for Image Quality Improvement and Dose Reduction in CT

Image-based quantitative assessment of tumor hypoxia

Frequent collaborators

Michael Milosevic

Caroline Chung

Kathy Han

Jinzi Zheng

Ivan Yeung

Christine Allen

Mary Gospodarowicz

Robert Weersink

Kazuhiro Yasufuku

Andrew Hope

John Kim

Catherine Coolens

Laura Dawson

Alejandro Berlin

Warren Foltz

Meredith Giuliani

Jonathan Irish

Kumaraswamy Nanthakumar

Gang Zheng

Payam Zahedi

Martin Post

Gelareh Zadeh

Mansoor Husain

Fei-Fei Liu

Shana Kelley