Faculty profile
Beverley Orser
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Read how they describe their research on their University of Toronto profile.
Latest papers
Corrigendum to 'Effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review and meta-analysis' (Br J Anaesth 2023; 131: 314-27).
British journal of anaesthesia · 2023
Inhalation of ACE2 as a therapeutic target on sex-bias differences in SARS-CoV-2 infection and variant of concern.
iScience · 2023
An open label pilot study of a dexmedetomidine-remifentanil-caudal anesthetic for infant lower abdominal/lower extremity surgery: The T REX pilot study.
Paediatric anaesthesia · 2019
Latest funding
- $1,147,500
Targeting inhibitory neurotransmission to preserve cognition after surgery
CIHR · 2026 · Nominated PI
- $730,576
The PLATform for INnovative Multicentre trials for comorbid chronic Pain and Depressive disorders (PLATINuM-PD)
CIHR · 2026 · Co-investigator
- $120,000
Mechanisms of GABA-A receptor redistribution after surgery: a target for preserving cognition
CIHR · 2025 · Supervisor
7 publications.
Corrigendum to 'Effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review and meta-analysis' (Br J Anaesth 2023; 131: 314-27).
Cuninghame S, Jerath A, Gorsky K, Sivajohan A, Francoeur C, Withington D, Burry L, Cuthbertson BH, Orser B, Martin C, Owen AM, Slessarev M, Sedating with Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects on Ventilatory Parameters and Survival study investigators
Inhalation of ACE2 as a therapeutic target on sex-bias differences in SARS-CoV-2 infection and variant of concern.
Onodera Y, Liang J, Li Y, Griffin B, Thanabalasingam T, Lu C, Zhu J, Liu M, Moraes T, Zheng W, Khateeb J, Khang J, Huang Y, Jerkic M, Nakane M, Baker A, Orser B, Chen YW, Wirnsberger G, Penninger JM, Rotstein OD, Slutsky AS, Li Y, Mubareka S, Zhang H
An open label pilot study of a dexmedetomidine-remifentanil-caudal anesthetic for infant lower abdominal/lower extremity surgery: The T REX pilot study.
Szmuk P, Andropoulos D, McGowan F, Brambrink A, Lee C, Lee KJ, McCann ME, Liu Y, Saynhalath R, Bong CL, Anderson BJ, Berde C, De Graaff JC, Disma N, Kurth D, Loepke A, Orser B, Sessler DI, Skowno JJ, von Ungern-Sternberg BS, Vutskits L, Davidson A
Ketamine augmentation for major depressive disorder and suicidal ideation: Preliminary experience in an inpatient psychiatry setting
Sinyor M, Williams M, Belo S, Orser B, Vincent M, Mah L, Zarate C, Castel S, Levitt AJ, Schaffer A
Evaluation of a preoperative checklist and team briefing among surgeons, nurses, and anesthesiologists to reduce failures in communication.
Lingard L, Regehr G, Orser B, Reznick R, Baker GR, Doran D, Espin S, Bohnen J, Whyte S
A GABAergic system in airway epithelium is essential for mucus overproduction in asthma
Xiang Y-Y, Wang S, Liu M, Hirota JA, Li J, Ju W, Fan Y, Kelly MM, Ye B, Orser B
Towards safer interprofessional communication: constructing a model of "utility" from preoperative team briefings.
Lingard L, Whyte S, Espin S, Baker GR, Orser B, Doran D
Targeting inhibitory neurotransmission to preserve cognition after surgery
Principal investigators: Orser, Beverley A
Keywords: Astrocyte-Derived Gaba; Gaba-A Receptors; General Anesthetics; Hippocampus; Perioperative Neurocognitive Disorders; Surgery; Tonic Inhibition; Transgenic Mice
The PLATform for INnovative Multicentre trials for comorbid chronic Pain and Depressive disorders (PLATINuM-PD)
Principal investigators: Ladha, Karim; Clarke, Hance A; Goel, Akash; Husain, Muhammad I; Rosenblat, Joshua D; Rosenbloom, Brittany; Voineskos, Daphne; Zrenner, Christoph D
Keywords: Chronic Pain; Depression; Platform Trial
Mechanisms of GABA-A receptor redistribution after surgery: a target for preserving cognition
Principal investigators: Yu, MeiFeng
Keywords: Cognition; Extrasynaptic; Gaba-A Receptor; Hippocampus; Memory; Tonic Inhibition
The Sustained Mood Improvement with Laughing Gas Exposure (SMILE) Trial
Principal investigators: Ladha, Karim; Husain, Muhammad I; Rosenblat, Joshua D
Keywords: Active Placebo; Depression Remission; Depression Response; Midazolam; Nitrous Oxide; Randomized Controlled Trial; Treatment Efficacy; Treatment-Resistant Depression
Cognitive Outcomes after Dexmedetomidine sedation in Cardiac Surgery: CODEX RCT
Principal investigators: Choi, Stephen
Keywords: Postoperative Cognitive Decline
Targeting GABA-A receptors to treat depression with nitrous oxide
Principal investigators: Brenna, Connor
Keywords: Behaviour; Cellular Neurobiology; Depression; Electrophysiology; Gaba-A Receptors; Mice; Molecular Neurobiology; Nitrous Oxide; Tonic Inhibition
Advancing Brain Outcomes in pediatric critically ill patients sedated with Volatile AnEsthestic Agents: A pilot multicentre randomized controlled trial (ABOVE Trial).
Principal investigators: Jerath, Angela; Cuthbertson, Brian H; Lalgudi Ganesan, Saptharishi; McKinnon, Nicole K; Slessarev, Marat
Keywords: Clinical Trial; Critical Care; Pediatric; Sedation
Advancing Brain Outcomes in pediatric critically ill patients sedated with Volatile AnEsthestic Agents: A pilot multicentre randomized controlled trial (ABOVE Trial).
Principal investigators: Jerath, Angela; Cuthbertson, Brian H; Lalgudi Ganesan, Saptharishi; McKinnon, Nicole K; Slessarev, Marat
Keywords: Clinical Trial; Critical Care; Pediatric; Sedation
Novel therapeutic targeting for cognitive deficits in depression and aging
Principal investigators: Sibille, Etienne
Keywords: Animal Studies; Cognition; Depression; Drug Development; Human Target Engagement; Mechanisms Of Disease; Pre-Clinical; Small Molecules
Targeting GABA-A receptors to mitigate persistent cognitive deficits induced by inflammation and general anesthetics
Principal investigators: Khodaei, Shahin
Keywords: Behaviour; Biochemistry; Cognition; Electrophysiology; Gaba-A Receptor; General Anesthetics; Hippocampus; Inflammation; Memory; Tonic Inhibition
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Paul O'Byrne and Mark David Inman: 72 shared papers
- Mark Sinyor and Ayal Schaffer: 71 shared papers
- Jeremy Hirota and Mark David Inman: 21 shared papers
- Claudio Martin and Marat Slessarev: 13 shared papers
- Mingyao Liu and Haibo Zhang: 13 shared papers
- Angela Jerath and Marat Slessarev: 10 shared papers
- Haibo Zhang and Samira Mubareka: 6 shared papers
- Claudio Martin and Angela Jerath: 4 shared papers
- Lisa Burry and Marat Slessarev: 4 shared papers
- Jeremy Hirota and Paul O'Byrne: 3 shared papers
- Jeremy Hirota and Samira Mubareka: 3 shared papers
- Margaret (Maggie) Anne Vincent and Mark Sinyor: 3 shared papers
- Margaret (Maggie) Anne Vincent and Ayal Schaffer: 3 shared papers
- Lisa Burry and Angela Jerath: 3 shared papers
- Beverley Orser and Mingyao Liu: 2 shared papers
- Beverley Orser and Sherry Espin: 2 shared papers
- Claudio Martin and Lisa Burry: 2 shared papers
- Andrew Baker and Haibo Zhang: 2 shared papers
- Jeremy Hirota and Beverley Orser: 1 shared paper
- Jeremy Hirota and Mingyao Liu: 1 shared paper
- Paul O'Byrne and Beverley Orser: 1 shared paper
- Mark David Inman and Beverley Orser: 1 shared paper
- Margaret (Maggie) Anne Vincent and Beverley Orser: 1 shared paper
- Beverley Orser and Claudio Martin: 1 shared paper
- Beverley Orser and Andrew Baker: 1 shared paper
- Beverley Orser and Haibo Zhang: 1 shared paper
- Beverley Orser and Samira Mubareka: 1 shared paper
- Beverley Orser and Lisa Burry: 1 shared paper
- Beverley Orser and Mark Sinyor: 1 shared paper
- Beverley Orser and Theo Moraes: 1 shared paper
- Beverley Orser and Angela Jerath: 1 shared paper
- Beverley Orser and Marat Slessarev: 1 shared paper
- Beverley Orser and Ayal Schaffer: 1 shared paper
- Mingyao Liu and Andrew Baker: 1 shared paper
- Mingyao Liu and Theo Moraes: 1 shared paper
- Andrew Baker and Theo Moraes: 1 shared paper
- Department of Medicine
- Department of Anesthesiology and Pain Medicine
- Department of Surgery
- Nursing
- Anesthesiology and Pain Management
- Department of Anesthesia
- Pharmacy
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Sherry Espin
Nursing
2 shared papers, latest 2008
Mingyao Liu
Department of Surgery
2 shared papers, latest 2023
Lisa Burry
Pharmacy
1 shared papers, latest 2023
Claudio Martin
Faculty
1 shared papers, latest 2023
Ayal Schaffer
Faculty
1 shared papers, latest 2018
Andrew Baker
Department of Anesthesiology and Pain Medicine
1 shared papers, latest 2023
Samira Mubareka
Department of Laboratory Medicine & Pathobiology
1 shared papers, latest 2023
Mark Sinyor
Faculty
1 shared papers, latest 2018
Haibo Zhang
Department of Anesthesia
1 shared papers, latest 2023
Marat Slessarev
Medicine
1 shared papers, latest 2023
Angela Jerath
Anesthesiology and Pain Management
1 shared papers, latest 2023
Theo Moraes
Faculty
1 shared papers, latest 2023
Jeremy Hirota
Department of Medicine
1 shared papers, latest 2007
Paul O'Byrne
Department of Medicine
1 shared papers, latest 2007
Mark David Inman
Department of Medicine
1 shared papers, latest 2007
Margaret (Maggie) Anne Vincent
Department of Medicine
1 shared papers, latest 2018
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Profile data last refreshed on September 26, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.