This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Discovery of FBP1 as novel therapeutic target and asiatic acid-hydrogen sulfide donors accelerate diabetic wound healing.
Journal of advanced research · 2026
Grey matter degeneration during multiple sclerosis is linked to activation of neuronal necroptosis by oxidized phosphatidylcholines.
Research square · 2026
SV2A PET reveals synaptic density loss in experimental autoimmune encephalomyelitis and in a pilot multiple sclerosis study.
Proceedings of the National Academy of Sciences of the United States of America · 2026 · senior author
Latest funding
- $849,150
Develop in vivo PET imaging probes for imaging AMPA receptor in multiple sclerosis
CIHR · 2026 · Nominated PI
- $711,450
Development of in vivo PET imaging methods using SV2A PET to evaluate synapse damages in multiple sclerosis
CIHR · 2025 · Nominated PI
- $761,175
Develop in vivo PET imaging probes for ROCK2 as a biomarker of early Alzheimer's disease.
CIHR · 2023 · Nominated PI
18 publications.
Discovery of FBP1 as novel therapeutic target and asiatic acid-hydrogen sulfide donors accelerate diabetic wound healing.
Wang S, Ye T, Shi L, Zheng C, Wang W, Dong L, Ou S, Li S, Wu J, Xu F, Hua H, Cheng M, Li D
Grey matter degeneration during multiple sclerosis is linked to activation of neuronal necroptosis by oxidized phosphatidylcholines.
Yu R, Park J, Ain QU, Yan G, Dignean RA, Zandee S, Klement W, Larouche S, Zheng C, Botterill JJ, Prat A, McGavern DB, Dong Y
SV2A PET reveals synaptic density loss in experimental autoimmune encephalomyelitis and in a pilot multiple sclerosis study.
Chia PHJ, Toyonaga T, Tong J, Le H, Dias M, Boyle AJ, Raymond R, Longbrake EE, Huang Y, Carson RE, Airas L, Vasdev N, Chen MK, Zheng C
Three-component synthesis of β-thio tertiary alkylamines from simple alkenes via SH2 homolytic substitution.
Wang H, Wang T, Li Y, He Q, Ma W, Guan X, Li Y, Bao Y, Zhao Y, Zhang Q, Vasdev N, Zheng C, Fu J
Iron-catalyzed three-component amino(radio)fluorination of alkenes to unprotected β-(radio)fluoroamines.
Li Y, Zhou Y, Bortolus MR, Zhang X, Wang Z, Liu D, Le H, Esezobor OZ, Ni J, Zhang Q, Vasdev N, Cheng GJ, Zheng C, Fu J
[18F]SynVesT-1 PET Detects SV2A Changes in the Spinal Cord and Brain of Rats with Spinal Cord Injury.
Chen B, Zheng C, Balayeva T, Toyonaga T, Wang X, Tong J, Mennie W, Mihailovic J, Coman D, Hyder F, Strittmatter SM, Carson RE, Huang Y, Cai Z
Development of Hydrogen Sulfide-Donating Silybin Derivatives with a Type-2 Diabetes Mellitus-Alleviating Effect through Improving Intestinal L-Cell Functions.
Li H, Ma Q, Li X, Zheng C, Lin L, Gu J, Huang X, Yang H, Xu H, Xu F, Hua H, Cheng M, Li D
Rock inhibitors in Alzheimer's disease.
Zheng C, Xia W, Zhang J
Radiosynthesis, In Vitro Characterization, and In Vivo PET Neuroimaging of [18F]F-4 for Tau Protein: A First-in-Human PET Study.
Lindberg A, Tong J, Zheng C, Mueller A, Kroth H, Stephens A, Mathis CA, Vasdev N
Structure-Guided Discovery of Subtype Selective SIRT6 Inhibitors with a β-Carboline Skeleton for the Treatment of Breast Cancer.
Liang C, Wang S, Feng D, Wang S, Zheng C, Qu Y, Wang W, Ma Y, Li H, Yang H, Cao H, Hua H, Cheng M, Li D
Develop in vivo PET imaging probes for imaging AMPA receptor in multiple sclerosis
Principal investigators: Zheng, Chao
Keywords: Ampa Radioligands; Assess Therapeutic Effects; Disease Detection; Glutamatergic Neurotransmission; Multiple Sclerosis; Pet Imaging; Radiopharmaceuticals
Development of in vivo PET imaging methods using SV2A PET to evaluate synapse damages in multiple sclerosis
Principal investigators: Zheng, Chao
Keywords: Assess Therapeutic Effects; Autoradiograph; Disease Detection; Longitudinal Study; Multiple Sclerosis; Pet Imaging; Radiopharmaceuticals; Synaptic Density; Synaptic Vesicle Glycoprotein 2a (Sv2a)
Develop in vivo PET imaging probes for ROCK2 as a biomarker of early Alzheimer's disease.
Principal investigators: Zheng, Chao
Keywords: Alzheimer'S Disease; Autoradiography; Brain Penetrant; Early Detection; Pet Imaging; Postmortem Human Brains; Radiopharmaceuticals; Rho-Associated Coiled-Coil Containing Protein Kinase 2; Rock2 Radioligands; Synaptic Vesicle Glycoprotein 2a
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Neil Vasdev and Chao Zheng: 4 shared papers
- Chao Zheng and Yifei Dong: 1 shared paper
- Biochemistry, Microbiology & Immunology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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