Faculty profile
Yifei Dong
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Saskatchewan directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Grey matter degeneration during multiple sclerosis is linked to activation of neuronal necroptosis by oxidized phosphatidylcholines.
Research square · 2026 · senior author
Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1β signaling.
Nature neuroscience · 2026 · senior author
Voluntary Long-Term Exercise by Female Mice Modulates Anxiety-Like Behavior and Motor Function but Minimally Impacts Acute Oxidative Injury in the Central Nervous System.
The European journal of neuroscience · 2025 · senior author
Latest funding
- $1,227,826
Using circulating microglia extracellular vesicles to discriminate microglia activation phenotype, and cognitive outcomes in comorbid AD and stroke
CIHR · 2026 · Co-investigator
- $1,093,950
Understanding oxidized phosphatidylcholines as novel mediators of chronic neurodegeneration and progressive multiple sclerosis.
CIHR · 2024 · Nominated PI
- $960,076
Cannabinoid-dependent effects of gestational Cannabis smoke exposure on behaviour and neurophysiology: implications for long-term offspring development
CIHR · 2024 · Co-investigator
10 publications.
Grey matter degeneration during multiple sclerosis is linked to activation of neuronal necroptosis by oxidized phosphatidylcholines.
Yu R, Park J, Ain QU, Yan G, Dignean RA, Zandee S, Klement W, Larouche S, Zheng C, Botterill JJ, Prat A, McGavern DB, Dong Y
Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1β signaling.
Yu R, Lozinski BM, Seifert A, Ta K, Zandee S, Kaushik DK, Park J, Klement W, Larouche S, Tsimikas S, Witztum JL, McGavern DB, Prat A, Dong Y
Voluntary Long-Term Exercise by Female Mice Modulates Anxiety-Like Behavior and Motor Function but Minimally Impacts Acute Oxidative Injury in the Central Nervous System.
Ta K, Yu R, Sedighipour Chafjiri M, Pioli KT, Glass AE, Anstey MP, Dignean RA, Botterill JJ, Pioli PD, Howland JG, Dong Y
Lipidomic Signatures in Microglial Extracellular Vesicles During Acute Inflammation: A Gateway to Neurological Biomarkers.
Ollen-Bittle N, Wang W, Bean KM, Zhao S, Buzatto AZ, Dong Y, Li L, Whitehead SN
Recycling gone wrong: how inflammation promotes neuronal stress.
Dong Y, Yong VW
Bruton Tyrosine Kinase in Lesions of Multiple Sclerosis and 3 of Its Models.
Li C, Morch MT, Gorter R, Lozinski B, Ghorbani S, Dong Y, Shen YA, Harp C, Zandee S, Klement W, Prat A, Yong VW
Emerging role of galectin 3 in neuroinflammation and neurodegeneration.
Lozinski BM, Ta K, Dong Y
Fibulin-2 is an extracellular matrix inhibitor of oligodendrocytes relevant to multiple sclerosis.
Ghorbani S, Li C, Lozinski BM, Moezzi D, D'Mello C, Dong Y, Visser F, Li H, Silva C, Khakpour M, Murray CJ, Tremblay MÈ, Xue M, Yong VW
Enhanced liver X receptor signalling reduces brain injury and promotes tissue regeneration following experimental intracerebral haemorrhage: roles of microglia/macrophages.
Zhang R, Dong Y, Liu Y, Moezzi D, Ghorbani S, Mirzaei R, Lozinski BM, Dunn JF, Yong VW, Xue M
Elevated Galectin-3 Is Associated with Aging, Multiple Sclerosis, and Oxidized Phosphatidylcholine-Induced Neurodegeneration.
Xue S, Lozinski BM, Ghorbani S, Ta K, D'Mello C, Yong VW, Dong Y
Using circulating microglia extracellular vesicles to discriminate microglia activation phenotype, and cognitive outcomes in comorbid AD and stroke
Principal investigators: Whitehead, Shawn N; Badhwar, Amanpreet; Edwards, Jodi D
Keywords: Alzheimer'S Disease; Biomarkers; Dementia; Microglia; Stroke
Understanding oxidized phosphatidylcholines as novel mediators of chronic neurodegeneration and progressive multiple sclerosis.
Principal investigators: Dong, Yifei
Keywords: Chronic Disease; Microglia; Multiple Sclerosis; Neurodegeneration; Neuroinflammation; Oxidized Phosphatidylcholine
Cannabinoid-dependent effects of gestational Cannabis smoke exposure on behaviour and neurophysiology: implications for long-term offspring development
Principal investigators: Howland, John G; Laprairie, Robert B
Keywords: Anxiety; Behaviour; Cannabinoid Receptor; Cognition; Cortex; Development; Imaging; Rna-Seq; Rodent Model
Understanding how macrophages respond to oxidized phosphatidylcholines
Principal investigators: Dong, Yifei
Keywords: Macrophage; Microglia; Oxidized phosphatidylcholine; Receptor-ligand interaction; TREM2
Understanding how macrophages respond to oxidized phosphatidylcholines
Principal investigators: Dong, Yifei
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Biochemistry, Microbiology & Immunology
- Chemistry
- Other
Co-authors at University of Saskatchewan, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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