Faculty profile
Clement Zai
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Latest papers
Neurocognitive correlates of polygenic risk for bipolar disorder among youth with and without bipolar disorder.
Journal of affective disorders · 2025
Epigenetic age dysregulation in individuals with bipolar disorder and schizophrenia.
Psychiatry research · 2022
Investigation of accelerated epigenetic aging in individuals experiencing suicidal ideation.
Schizophrenia research · 2022
Latest funding
- $934,491
Mitochondrial Genetics in Relation to Brain Metabolism and Energy Phenotypes in Bipolar Disorder Across the Lifespan
CIHR · 2026 · Co-investigator
- $726,750
Impact of Genomic Factors in Accidental Lethal Opioid Overdose
CIHR · 2025 · Co-investigator
- $1,246,950
Coronary Microvascular Reactivity in Relation to Brain Structure, Cardiovascular Genetics, and Serious Mental Illness in Youth
CIHR · 2024 · Co-investigator
38 publications.
Neurocognitive correlates of polygenic risk for bipolar disorder among youth with and without bipolar disorder.
Jiang X, Zai C, Mio M, Dimick MK, Sultan AA, Young LT, Goldstein BI
Epigenetic age dysregulation in individuals with bipolar disorder and schizophrenia.
Jeremian R, Malinowski A, Chaudhary Z, Srivastava A, Qian J, Zai C, Adanty C, Fischer CE, Burhan AM, Kennedy JL, Borlido C, Gerretsen P, Graff A, Remington G, Vincent JB, Strauss JS, De Luca V
Investigation of accelerated epigenetic aging in individuals experiencing suicidal ideation.
Dada O, Jeremian R, Dai N, Strauss J, Zai C, Graff A, De Luca V
Recent health-related stressful life events predictive of emergent suicidal ideation in schizophrenia.
Tasmim S, Bani-Fatemi A, Dada OD, Wang KZ, Zai C, Graff A, Gerretsen P, De Luca V
Epigenetic studies in suicidal ideation and behavior.
Dada O, Qian J, Al-Chalabi N, Kolla NJ, Graff A, Zai C, Gerretsen P, De Luca V
Mediating effect of genome-wide DNA methylation on suicidal ideation induced by perceived stress.
Dada O, Adanty C, Dai N, Zai C, Gerretsen P, Graff A, de Luca V
Genome wide study of tardive dyskinesia in schizophrenia.
Lim K, Lam M, Zai C, Tay J, Karlsson N, Deshpande SN, Thelma BK, Ozaki N, Inada T, Sim K, Chong SA, Lencz T, Liu J, Lee J
The pharmacogenetics of opioid treatment for pain management.
Singh A, Zai C, Mohiuddin AG, Kennedy JL
Genome-wide methylation association with current suicidal ideation in schizophrenia.
Bani-Fatemi A, Adanty C, Dai N, Dada O, Strauss J, Zai C, Gerretsen P, Graff A, De Luca V
Association Study of OPRM1 Gene in a Sample of Schizophrenia Patients With Alcohol Dependence or Abuse.
Gendy MNS, Zai C, Le Foll B, Kennedy JL
Mitochondrial Genetics in Relation to Brain Metabolism and Energy Phenotypes in Bipolar Disorder Across the Lifespan
Principal investigators: Goldstein, Benjamin I
Keywords: Activity; Bipolar Disorder; Energy; Genetics; Lifespan; Mitochondria; Neuroimaging; Sex Differences
Impact of Genomic Factors in Accidental Lethal Opioid Overdose
Principal investigators: Mueller, Daniel J; Le Foll, Bernard
Keywords: Genomics; Lethal Overdose; Opioids; Pharmacogenetics; Polygenic Risk Scores; Substance Use Disorder
Coronary Microvascular Reactivity in Relation to Brain Structure, Cardiovascular Genetics, and Serious Mental Illness in Youth
Principal investigators: Goldstein, Benjamin I; Friedrich, Matthias G; Raucher-Chéné, Delphine
Keywords: Cardiac Imaging; Cardiovascular Risk Factors; Genetics; Microvessels; Neuroimaging; Prevention; Severe Mental Illness; Sex Differences; Youth
Predicting risk for treatment-resistant depression using pharmacogenomic-based modeling
Principal investigators: Mueller, Daniel J; Kloiber, Stefan M
Keywords: Depression; Machine Learning; Mental Health; Pharmacogenomics; Sex Differences
Risk and protective factors of post-traumatic stress disorder in the CLSA dataset
Principal investigators: Zai, Clement
Keywords: Childhood Adversities; Elderly Abuse; Healthcare Utilization; Lgbtq2s+; Mental Health; Military Veterans; Physical Activities; Post-Traumatic Stress Disorder; Social Support
Influence of polygenic risk scores on longitudinal disease trajectories of individuals with schizophrenia spectrum disorders
Principal investigators: Kennedy, James L; Tiwari, Arun K; Zai, Clement
Keywords: Disease Severity; Functional Outcomes; Pharmacogenetics; Response; Schizophrenia; Schizophrenia Spectrum Disorders; Side Effects
Development, validation and benefits of a genetic risk model for antipsychotic-induced weight gain
Principal investigators: Mueller, Daniel J
Keywords: Antipsychotics; Genetic Risk Model; Genetics; Gwas; Health Care Costs; Metabolic Syndrome; Pharmacogenetics; Psychopharmacology; Side Effects; Weight Gain
Genetics and Epigenetics of Serotonin System in Suicidal Behaviour: CpG SNP Mapping, Methylation and Allelic Imbalance Analysis
Principal investigators: De Luca, Vincenzo
Keywords: Epigenetics; Genetics; Methylation; Suicide
Genetics and Epigenetics of Serotonin System in Suicidal Behaviour: CpG SNP Mapping, Methylation and Allelic Imbalance Analysis
Principal investigators: De Luca, Vincenzo
Keywords: Epigenetics; Genetics; Methylation; Suicide
Strategies for gene discovery in schizophrenia: subphenotypes, deep sequencing, and interactions
Principal investigators: Kennedy, James L
Keywords: Association; Endophenotypes; Eye Tracking; Facial Dysmorphology; Gene Sequencing; Gene-Environment Interactions; Response; Schizophrenia
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Gary Remington and Philip Gerretsen: 69 shared papers
- Martin Alda and Gustavo Turecki: 31 shared papers
- John Strauss and Clement Zai: 13 shared papers
- Gustavo Turecki and Stefan Kloiber: 12 shared papers
- Bernard Le Foll and Stefan Kloiber: 11 shared papers
- Philip Gerretsen and Clement Zai: 9 shared papers
- John Strauss and Philip Gerretsen: 7 shared papers
- Bernard Le Foll and Clement Zai: 5 shared papers
- Gary Remington and Clement Zai: 5 shared papers
- Bernard Le Foll and John Strauss: 4 shared papers
- Gary Remington and John Strauss: 4 shared papers
- Gary Remington and Daniel Felsky: 4 shared papers
- Martin Alda and Stefan Kloiber: 3 shared papers
- Nathan Kolla and Philip Gerretsen: 3 shared papers
- John Strauss and Albert Wong: 3 shared papers
- Philip Gerretsen and Daniel Felsky: 3 shared papers
- Albert Wong and Clement Zai: 3 shared papers
- Bernard Le Foll and Albert Wong: 2 shared papers
- Bernard Le Foll and Daniel Felsky: 2 shared papers
- Patrick McGrath and Martin Alda: 2 shared papers
- Patrick McGrath and Gustavo Turecki: 2 shared papers
- Patrick McGrath and Patrick McGrath: 2 shared papers
- Martin Alda and Patrick McGrath: 2 shared papers
- Gustavo Turecki and Patrick McGrath: 2 shared papers
- Patrick McGrath and Clement Zai: 1 shared paper
- Martin Alda and Clement Zai: 1 shared paper
- Lei Sun and Clement Zai: 1 shared paper
- Lei Sun and Daniel Felsky: 1 shared paper
- Gustavo Turecki and Mario Masellis: 1 shared paper
- Gustavo Turecki and Clement Zai: 1 shared paper
- Gary Remington and Nathan Kolla: 1 shared paper
- Gary Remington and Arun Tiwari: 1 shared paper
- Nathan Kolla and John Strauss: 1 shared paper
- Nathan Kolla and Clement Zai: 1 shared paper
- Mario Masellis and Arun Tiwari: 1 shared paper
- Mario Masellis and Clement Zai: 1 shared paper
- John Strauss and John Vincent: 1 shared paper
- John Strauss and Arun Tiwari: 1 shared paper
- Patrick McGrath and Clement Zai: 1 shared paper
- John Vincent and Albert Wong: 1 shared paper
- John Vincent and Clement Zai: 1 shared paper
- Stefan Kloiber and Clement Zai: 1 shared paper
- Arun Tiwari and Clement Zai: 1 shared paper
- Clement Zai and Daniel Felsky: 1 shared paper
- Psychiatry
- Research Imaging Center
- Epidemiology Division
- Department of Family and Community Medicine
- Neurosciences
- Department of Psychiatry
- Biostatistics Division
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
John Strauss
Faculty
13 shared papers, latest 2022
Philip Gerretsen
Research Imaging Center
9 shared papers, latest 2022
Gary Remington
Research Imaging Center
5 shared papers, latest 2022
Bernard Le Foll
Department of Family and Community Medicine
5 shared papers, latest 2019
Albert Wong
Neurosciences
3 shared papers, latest 2016
Daniel Felsky
Department of Psychiatry
1 shared papers, latest 2013
Nathan Kolla
Psychiatry
1 shared papers, latest 2019
Mario Masellis
Medicine
1 shared papers, latest 2011
Patrick McGrath
Faculty
1 shared papers, latest 2019
John Vincent
Faculty
1 shared papers, latest 2016
Stefan Kloiber
Faculty
1 shared papers, latest 2019
Arun Tiwari
Faculty
1 shared papers, latest 2011
Patrick McGrath
Faculty
1 shared papers, latest 2019
Martin Alda
Psychiatry
1 shared papers, latest 2019
Lei Sun
Biostatistics Division
1 shared papers, latest 2012
Gustavo Turecki
Psychiatry
1 shared papers, latest 2019
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Profile data last refreshed on July 30, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.