Dang Nguyen, University of Toronto

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Direct binding of the C-terminal sequences of Bim and Bak contributes to efficient Bak activation
Cell Death and Differentiation · 2026 · first author
Nesprin-2 contains BH3-like motifs that can promote cell death
Cell Death Discovery · 2025
BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains
EMBO Reports · 2024

All 8 publications

8 publications.

01

Direct binding of the C-terminal sequences of Bim and Bak contributes to efficient Bak activation

Dang Nguyen, Sabina Trebinjac, Tobias B. Beigl, Frank Eßmann, Kathryn M. Murphy, David William Andrews

Cell Death and Differentiation2026First authorOpen Access

DOI: 10.1038/s41418-026-01848-w PMID: 42693245

02

Nesprin-2 contains BH3-like motifs that can promote cell death

Hila Zohar, Amit Kessel, Liora Lindenboim, Dang Quan Nguyen, Nir Ben‐Tal, Gregg G. Gundersen, Howard J. Worman, David William Andrews, Reuven Stein

Cell Death Discovery20252 citationsOpen Access

DOI: 10.1038/s41420-025-02534-5 PMID: 40461467

03

BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains

Tobias B. Beigl, Alexander Paul, Thomas Fellmeth, Dang Quan Nguyen, Lynn Barber, Sandra Weller, Benjamin Schäfer, Bernhard F. Gillissen, Walter E. Aulitzky, Hans‐Georg Kopp, Markus Rehm, David William Andrews, Kristýna Pluháčková, Frank Eßmann

EMBO Reports202421 citationsOpen Access

DOI: 10.1038/s44319-024-00206-6 PMID: 39048751

04

The C-terminal sequences of Bcl-2 family proteins mediate interactions that regulate cell death

Dang Quan Nguyen, Elizabeth J. Osterlund, Justin Kale, David William Andrews

Biochemical Journal202418 citationsFirst authorOpen Access

DOI: 10.1042/bcj20210352 PMID: 38985308

05

Endoplasmic reticulum protein BIK binds to and inhibits mitochondria-localized antiapoptotic proteins

Osterlund EJ, Hirmiz N, Nguyen D, Pemberton JM, Fang Q, Andrews DW

Journal of Biological Chemistry202316 citationsOpen Access

DOI: 10.1016/j.jbc.2022.102863 PMID: W4313529858

06

The carboxyl-terminal sequence of PUMA binds to both anti-apoptotic proteins and membranes

Pemberton JM, Nguyen D, Osterlund EJ, Schormann W, Pogmore JP, Hirmiz N, Leber B, Andrews DW

eLife202310 citationsOpen Access

DOI: 10.7554/elife.88329

07

The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

Chi X, Nguyen D, Pemberton JM, Oesterlund EJ, Liu Q, Brahmbhatt H, Zhang Z, Lin J, Leber B, Andrews DW

eLife202047 citationsOpen Access

DOI: 10.7554/elife.44525

08

Elevated Temperature Differentially Influences Effector-Triggered Immunity Outputs in Arabidopsis.

Menna A, Nguyen D, Guttman DS, Desveaux D

Frontiers in plant science201560 citationsOpen Access

DOI: 10.3389/fpls.2015.00995 PMID: 26617631

Frequent collaborators

Department of Medicine
Department of Cell & Systems Biology
Biostatistics Division
Department of Engineering Physics

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

David Andrews

Biostatistics Division

7 shared papers, latest 2026

Brian Leber

Department of Medicine

2 shared papers, latest 2023

Qiyin Fang

Department of Engineering Physics

1 shared papers, latest 2023

David Guttman

Department of Cell & Systems Biology

1 shared papers, latest 2015

Darrell Desveaux

Department of Cell & Systems Biology

1 shared papers, latest 2015

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Subject: Prospective PhD student Dear Professor Nguyen, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Direct binding of the C-terminal sequences of Bim and Bak contributes to efficient Bak activation" (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]