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Derek MacFadden

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Assistant ProfessorEpidemiology DivisionUniversity of Toronto

Derek MacFadden

Assistant Professor

Epidemiology Division

Dalla Lana School of Public Health

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
3 publications in the last five years, latest in 2025.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 8 research grants (8 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Antimicrobial Resistance Adaptive Platform Trial Antibiotic De-Escalation Bloodstream Infection Central Venous Catheter Infection Gram Negative Bacteremia Covid-19 Environmental Surveillance

Latest papers

The Burden of Antimicrobial Resistant Bacteremia in Ontario: A Population-Wide Analysis of Attributable Mortality From 110 Pathogen-Antibiotic Combinations
Clinical Infectious Diseases · 2025
The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections
Microbiology Spectrum · 2023 · senior author
The Collapse of Infectious Disease Diagnoses Commonly Due to Communicable Respiratory Pathogens During the Coronavirus Disease 2019 Pandemic: A Time Series and Hierarchical Clustering Analysis
Open Forum Infectious Diseases · 2022 · senior author

All 8 publications

Latest funding

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections
CIHR · 2025 · Principal investigator
$1,908,674
Avian influenza suRveillance in Companion animal and Human healthcare settings [ARCH]
CIHR · 2024 · Principal investigator
$150,000
Transforming Sepsis Care: Robust prediction and decision making leveraging the Social Determinants of Health
CIHR · 2024 · Co-investigator
$1,996,903

All 19 grants and awards

8 publications.

The Burden of Antimicrobial Resistant Bacteremia in Ontario: A Population-Wide Analysis of Attributable Mortality From 110 Pathogen-Antibiotic Combinations

Brown KA, Fridman DJ, Garber GE, Johnstone J, Langford BJ, Leung V, MacFadden D, Patel SN, Schwartz KL, Sander B

Clinical Infectious Diseases20256 citations

DOI: 10.1093/cid/ciaf213

The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections

Driedger M, Daneman N, Brown K, Gold WL, Jorgensen SCJ, Maxwell C, Schwartz KL, Morris AM, Thiruchelvam D, Langford B

Microbiology Spectrum20235 citationsSenior author

DOI: 10.1128/spectrum.02630-23

The Collapse of Infectious Disease Diagnoses Commonly Due to Communicable Respiratory Pathogens During the Coronavirus Disease 2019 Pandemic: A Time Series and Hierarchical Clustering Analysis

Zhang A, Surette MD, Schwartz KL, Brooks JI, Bowdish DME, Mahdavi R, Manuel DG, Talarico R, Daneman N, Shurgold J

Open Forum Infectious Diseases20229 citationsSenior authorOpen Access

DOI: 10.1093/ofid/ofac205 PMID: W4224288966

Cognitive Biases to Consider in Non-convulsive Status Epilepticus Presenting in a Hematologic Malignancy.

Sawicka KM, MacFadden D, McCredie VA

Neurocritical care2020

DOI: 10.1007/s12028-020-01071-6 PMID: 32779127

Cumulative Probability of Receiving an Antibiotic Prescription over Time.

Olesen SW, MacFadden D, Grad YH

The New England journal of medicine2019

DOI: 10.1056/nejmc1816699 PMID: 31067381

Assessment of the potential for international dissemination of Ebola virus via commercial air travel during the 2014 west African outbreak.

Bogoch II, Creatore MI, Cetron MS, Brownstein JS, Pesik N, Miniota J, Tam T, Hu W, Nicolucci A, Ahmed S, Yoon JW, Berry I, Hay SI, Anema A, Tatem AJ, MacFadden D, German M, Khan K

Lancet (London, England)2015

DOI: 10.1016/s0140-6736(14)61828-6 PMID: 25458732

Glioblastoma management in the temozolomide era: have we improved outcome?

Lwin Z, MacFadden D, Al-Zahrani A, Atenafu E, Miller BA, Sahgal A, Menard C, Laperriere N, Mason WP

Journal of neuro-oncology2013

DOI: 10.1007/s11060-013-1230-3 PMID: 23979682

Clinical evaluation of stereotactic target localization using 3-Tesla MRI for radiosurgery planning.

MacFadden D, Zhang B, Brock KK, Hodaie M, Laperriere N, Schwartz M, Tsao M, Stainsby J, Lockwood G, Mikulis D, Ménard C

International journal of radiation oncology, biology, physics2010First author

DOI: 10.1016/j.ijrobp.2009.03.020 PMID: 19515512

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Principal investigatorCIHR2025Project Grant

Principal investigators: Daneman, Nick; Fowler, Robert A; Johnstone, Jennie; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Ong, Sean W; Pinto, Ruxandra; Rogers, Benjamin A

Keywords: Adaptive Platform Trial; Antibiotic De-Escalation; Antibiotic Duration; Antibiotic Oral Switch; Antimicrobial Resistance; Bloodstream Infection; Central Venous Catheter Infection; Gram Negative Bacteremia; Randomized Clinical Trial

$1,908,674

Avian influenza suRveillance in Companion animal and Human healthcare settings [ARCH]

Principal investigatorCIHR2024Catalyst Grant: Avian Influenza OneHealth Research

Principal investigators: Fralick, Michael P; Hug, Laura A; Kassen, Rees; MacFadden, Derek R; Nott, Caroline; Wong, Alex

Keywords: Animal Shelters; Avian Influenza A; Environmental Surface Surveillance; H5n1; Hospitals; One Health; Pandemic Surveillance; Veterinary Clinics; Whole Genome Sequencing; Wildlife Rehabilitation

$150,000

Transforming Sepsis Care: Robust prediction and decision making leveraging the Social Determinants of Health

Co-investigatorCIHR2024Team Grant: Embracing Diversity to Achieve Precision & Health Equity - Aging

Principal investigators: Gopalkrishnan, Rahul; Razak, Fahad; Richard, Lucie; Siddiqi, Arjumand; Verma, Amol

Keywords: Equity In Predictive Models; Machine Learning/Artificial Intelligence In Healthcare; Sepsis; Social Determinants Of Health

$1,996,903

A pragmatic randomized trial to evaluate the effect of a peer-comparison feedback letter on antimicrobial use in hospital-based physicians

Co-investigatorCIHR2023Project Grant

Principal investigators: Razak, Fahad; Daneman, Nick; Desveaux, Laura; Ivers, Noah M; McIntyre, Mark; Morris, Andrew M; Schwartz, Kevin L; Taljaard, Monica; Verma, Amol

Keywords: Antimicrobial Resistance; Antimicrobial Stewardship; Inpatient Care; Peer-Comparison Feedback Reporting; Pragmatic Randomized Trial

$634,949

Surveillance of Healthcare and Ambient Pathogens in our Environments and Spaces [SHAPES]

Principal investigatorCIHR2023Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Fralick, Michael P; Kassen, Rees; MacFadden, Derek R; Nott, Caroline; Wong, Alex

Keywords: Covid-19; Environmental Surveillance; Influenza; Long-Term Care Homes; Pathogen Surveillance; Respiratory Syncytial Virus (Rsv); Sars-Cov-2

$100,000

A pragmatic randomized trial to evaluate the effect of a peer-comparison feedback letter on antimicrobial use in hospital-based physicians

Co-investigatorCIHR2023Project Grant - PA: ECR Antimicrobial Resistance Multi-Year Grant

Principal investigators: Razak, Fahad; Desveaux, Laura; Ivers, Noah M; McIntyre, Mark; Morris, Andrew M; Schwartz, Kevin L; Taljaard, Monica; Verma, Amol

Keywords: Antimicrobial Resistance; Antimicrobial Stewardship; Inpatient Care; Peer-Comparison Feedback Reporting; Pragmatic Randomized Trial

$300,000

Surveillance of Healthcare and Ambient Pathogens in our Environments and Spaces [SHAPES]

Principal investigatorCIHR2022Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Fralick, Michael P; Castellani, Lucas; Hug, Laura A; Kassen, Rees; MacFadden, Derek R; Nott, Caroline; Thampi, Nisha; Wong, Alex

Keywords: Clostridioides Difficile (C. Difficile); Covid-19; Environmental Surveillance; Influenza; Long-Term Care Homes; Nosocomial Infections; Pathogen Surveillance; Respiratory Syncytial Virus (Rsv); Sars-Cov-2; Vancomycin-Resistant Enterococcus (Vre)

$100,000

Investigating variation in the inpatient allocation of scarce COVID-19 therapeutics: Equity and Clinical Outcomes

Co-investigatorCIHR2022Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Razak, Fahad; Baker, Andrew J; Chan, Timothy; Gibson, Jennifer; Leung, Elizabeth; Mamdani, Muhammad; Morris, Andrew M; Pai, Menaka; Rosella, Laura C; Sarhangian, Vahid; Siddiqi, Arjumand; Verma, Amol

Keywords: Covid-19; Drug Shortages; Ethical Framework; Health Equity; Health Systems; Medications; Patient Outcomes; Processes Of Inpatient Care; Resource Allocation

$100,000

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Principal investigatorCIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

Principal investigators: Daneman, Nick; Murthy, Srinivas; Yamamura, Deborah L; Fowler, Robert A; Johnstone, Jennie; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Paterson, David L; Rogers, Benjamin A; Yahav, Dafna

Keywords: Adaptive Platform Trial; Antibiotic De-Escalation; Antibiotic Step-Down; Antimicrobial Resistance; Bloodstream Infection; Central Venous Catheter Infection; Gram Negative Bacteremia; Randomized Controlled Trial

$729,947

Investigating variation in the inpatient allocation of scarce COVID-19 therapeutics: Equity and Clinical Outcomes

Co-investigatorCIHR2022Pro. Gr. - PA: Pandemic Preparedness and Health Emergencies: ECI Grant

Keywords: Covid-19; Drug Shortage; Health Equity; Health Systems; Medications; Patient Outcomes; Processes Of Inpatient Care; Resource Allocation

$400,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on July 30, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Derek MacFadden

Research

Latest papers

Latest funding

The Burden of Antimicrobial Resistant Bacteremia in Ontario: A Population-Wide Analysis of Attributable Mortality From 110 Pathogen-Antibiotic Combinations

The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections

The Collapse of Infectious Disease Diagnoses Commonly Due to Communicable Respiratory Pathogens During the Coronavirus Disease 2019 Pandemic: A Time Series and Hierarchical Clustering Analysis

Cognitive Biases to Consider in Non-convulsive Status Epilepticus Presenting in a Hematologic Malignancy.

Cumulative Probability of Receiving an Antibiotic Prescription over Time.

Assessment of the potential for international dissemination of Ebola virus via commercial air travel during the 2014 west African outbreak.

Glioblastoma management in the temozolomide era: have we improved outcome?

Clinical evaluation of stereotactic target localization using 3-Tesla MRI for radiosurgery planning.

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Avian influenza suRveillance in Companion animal and Human healthcare settings [ARCH]

Transforming Sepsis Care: Robust prediction and decision making leveraging the Social Determinants of Health

A pragmatic randomized trial to evaluate the effect of a peer-comparison feedback letter on antimicrobial use in hospital-based physicians

Surveillance of Healthcare and Ambient Pathogens in our Environments and Spaces [SHAPES]

A pragmatic randomized trial to evaluate the effect of a peer-comparison feedback letter on antimicrobial use in hospital-based physicians

Surveillance of Healthcare and Ambient Pathogens in our Environments and Spaces [SHAPES]

Investigating variation in the inpatient allocation of scarce COVID-19 therapeutics: Equity and Clinical Outcomes

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Investigating variation in the inpatient allocation of scarce COVID-19 therapeutics: Equity and Clinical Outcomes

Frequent collaborators

Derek MacFadden

Nick Daneman

Derek MacFadden

Derek MacFadden

Bradley Langford

Jennie Johnstone

Isha Berry

Bradley Langford

Mojgan Hodaie

Colleen Maxwell

Beate Sander

Elizabeth Leung

Dawn Bowdish

Kamran Khan

David Mikulis