Research
Read how they describe their research on their University of Toronto profile.
Latest papers
BAFFR-CAR T cells (PMB-CT01) show promising safety and anti-leukemia efficacy in relapsed/refractory B-cell ALL patients after CD19-targeted therapy failure, including CD19-negative disease
Blood · 2025
BAFFR-CAR T cells (PMB-CT01) demonstrate durable responses and manageable toxicities in relapsed/refractory B-cell lymphomas with prior CD19-directed therapy failure or CD19-negative disease
Blood · 2025
PMB-CT01 (BAFFR-CAR T cell) therapy to examine preliminary safety and clinical responses in patients with B-cell malignancies who are ineligible for or failed CD19-directed therapy, including CD19-negative disease.
Journal of Clinical Oncology · 2024
Latest funding
- $42,000
CRP-ductin: function and regulation
NSERC · 1997 · Co-investigator
74 publications.
BAFFR-CAR T cells (PMB-CT01) show promising safety and anti-leukemia efficacy in relapsed/refractory B-cell ALL patients after CD19-targeted therapy failure, including CD19-negative disease
Ibrahim Taha Aldoss, Xiuli Wang, Lu Chen, Joo Young Song, Karamjeet Sandhu, Alan Macias, Neguine Sanani, Baishakhi Barva, Min Guan, Ruby Espinosa, Sandrine Puverel, Qing Liu-Michael, Hazel Cheng, Guido Marcucci, Elizabeth E. Budde, Larry W. Kwak, Stephen J. Forman
BAFFR-CAR T cells (PMB-CT01) demonstrate durable responses and manageable toxicities in relapsed/refractory B-cell lymphomas with prior CD19-directed therapy failure or CD19-negative disease
Elizabeth E. Budde, Marissa Del Real, John H. Baird, Lu Chen, Joo Young Song, Xiuli Wang, Swetha Thiruvengadam, Marie Hu, Alan Macias, Emanuela C. Marcucci, Soung-chul Cha, Zhenyuan Dong, Teresa S. Kim, Baishakhi Barva, Sandrine Puverel, Qing Liu-Michael, Hazel Cheng, Stephen J. Forman, Larry W. Kwak
PMB-CT01 (BAFFR-CAR T cell) therapy to examine preliminary safety and clinical responses in patients with B-cell malignancies who are ineligible for or failed CD19-directed therapy, including CD19-negative disease.
Lihua Elizabeth Budde, Marissa Del Real, John H. Baird, Lu Chen, Joo Young Song, Xiuli Wang, Swetha Kambhampati, Alan Macias, Teresa S. Kim, Sylvia Dulan, Baishakhi Barva, Min Guan, Ruby Espinosa, Sandrine Puverel, Katrin Tiemann, Hazel Cheng, Stephen J. Forman, Larry W. Kwak, Ibrahim Taha Aldoss
Null mutations of NEUROG3 are associated with delayed-onset diabetes mellitus.
Solorzano-Vargas RS, Bjerknes M, Wang J, Wu SV, Garcia-Careaga MG, Pitukcheewanont P, Cheng H, German MS, Georgia S, Martín MG
The cellular regulators PTEN and BMI1 help mediate NEUROGENIN-3-induced cell cycle arrest.
Solorzano-Vargas RS, Bjerknes M, Wu SV, Wang J, Stelzner M, Dunn JCY, Dhawan S, Cheng H, Georgia S, Martín MG
Multiphoton Activation of Photo-Strain-Promoted Azide Alkyne Cycloaddition "Click" Reagents Enables in Situ Labeling with Submicrometer Resolution.
McNitt CD, Cheng H, Ullrich S, Popik VV, Bjerknes M
Facile Quenching and Spatial Patterning of Cylooctynes via Strain-Promoted Alkyne-Azide Cycloaddition of Inorganic Azides.
Bjerknes M, Cheng H, McNitt CD, Popik VV
epithelium Multipotential stem cells in adult mouse gastric
Matthew Bjerknes, Hazel Cheng
804 EDEM3 Controls NEUROGENIN-3 Protein's Half-Life by Inhibiting a Specific Ring Finger E3 Ligase, RNF128 (GRAIL), Attenuated NEUROG3 Degradation
Martı́n G. Martı́n, R. Sergio Solórzano-Vargas, Senta K. Georgia, Jiafang Wang, Shuping S. Wu, Matthew Bjerknes, Hazel Cheng
789 A Novel Dominant Negative Frame-Shift Mutation of NEUROGENIN-3 in a Child with Enteric Anendocrinosis
Martı́n G. Martı́n, R. Sergio Solórzano-Vargas, Manuel Garcia‐Careaga, Senta K. Georgia, Jiafang Wang, Matthew Bjerknes, Hazel Cheng
CRP-ductin: function and regulation
Principal investigators: Bjerknes, Matthew
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
- Steven Gallinger and Bharati Bapat: 42 shared papers
- Matthew Bjerknes and Hazel Cheng: 8 shared papers
- Tak Mak and Steven Gallinger: 4 shared papers
- Tak Mak and Bharati Bapat: 3 shared papers
- Tak Mak and Hazel Cheng: 2 shared papers
- Ian Young and Hazel Cheng: 2 shared papers
- Steven Gallinger and Hazel Cheng: 2 shared papers
- Bharati Bapat and Hazel Cheng: 2 shared papers
- Christopher McCulloch and Hazel Cheng: 1 shared paper
- Tarik Möröy and Matthew Bjerknes: 1 shared paper
- Tarik Möröy and Hazel Cheng: 1 shared paper
- Molly Allen and Hazel Cheng: 1 shared paper
- Department of Medicine
- Department of Laboratory Medicine & Pathobiology
- School of Occupational and Environmental Hygiene
- Department of Surgery
- Department of Immunology
- Department of Cell & Systems Biology
- Institut de recherches cliniques de Montréal
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Matthew Bjerknes
Department of Medicine
8 shared papers, latest 2020
Tak Mak
Department of Immunology
2 shared papers, latest 1996
Ian Young
School of Occupational and Environmental Hygiene
2 shared papers, latest 1968
Steven Gallinger
Department of Surgery
2 shared papers, latest 1996
Bharati Bapat
Department of Laboratory Medicine & Pathobiology
2 shared papers, latest 1996
Tarik Möröy
Institut de recherches cliniques de Montréal
1 shared papers, latest 2011
Molly Allen
Department of Medicine
1 shared papers, latest 1990
Christopher McCulloch
Department of Cell & Systems Biology
1 shared papers, latest 1986
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Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.