This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.
Latest papers
Novel c.G630A TCIRG1 mutation causes aberrant splicing resulting in an unusually mild form of autosomal recessive osteopetrosis.
Journal of cellular biochemistry · 2019 · senior author
V-ATPases Containing a3 Subunit Play a Direct Role in Enamel Development in Mice.
Journal of cellular biochemistry · 2017 · senior author
Activity-independent targeting of mTOR to lysosomes in primary osteoclasts.
Scientific reports · 2017 · senior author
Latest funding
- $100,000
Role of lysosomal pH in osteoclasts
CIHR · 2015 · Nominated PI
12 publications.
Novel c.G630A TCIRG1 mutation causes aberrant splicing resulting in an unusually mild form of autosomal recessive osteopetrosis.
Zirngibl RA, Wang A, Yao Y, Manolson MF, Krueger J, Dupuis L, Mendoza-Londono R, Voronov I
V-ATPases Containing a3 Subunit Play a Direct Role in Enamel Development in Mice.
Johnson L, Ganss B, Wang A, Zirngibl RA, Johnson DE, Owen C, Bradley G, Voronov I
Activity-independent targeting of mTOR to lysosomes in primary osteoclasts.
Wang A, Carraro-Lacroix LR, Owen C, Gao B, Corey PN, Tyrrell P, Brumell JH, Voronov I
DEL1 - a new player in periodontal disease?
Voronov I
Editorial: Flt3 ligand-friend or foe?
Voronov I, Manolson MF
Lysosomal pH Plays a Key Role in Regulation of mTOR Activity in Osteoclasts.
Hu Y, Carraro-Lacroix LR, Wang A, Owen C, Bajenova E, Corey PN, Brumell JH, Voronov I
The R740S mutation in the V-ATPase a3 subunit results in osteoclast apoptosis and defective early-stage autophagy.
Ochotny N, Voronov I, Owen C, Aubin JE, Manolson MF
The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis.
Voronov I, Ochotny N, Jaumouillé V, Owen C, Manolson MF, Aubin JE
Osteopetrosis mutation R444L causes endoplasmic reticulum retention and misprocessing of vacuolar H+-ATPase a3 subunit.
Bhargava A, Voronov I, Wang Y, Glogauer M, Kartner N, Manolson MF
The V-ATPase a3 subunit mutation R740S is dominant negative and results in osteopetrosis in mice.
Ochotny N, Flenniken AM, Owen C, Voronov I, Zirngibl RA, Osborne LR, Henderson JE, Adamson SL, Rossant J, Manolson MF, Aubin JE
Role of lysosomal pH in osteoclasts
Principal investigators: Voronov, Irina
Keywords: Autophagy; Lysosomal Ph; Mtor; Osteoclasts; Rheumatoid Arthritis
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Research Institute
- Institute of Biomaterials and Biomedical Engineering
- Dentistry
- Department of Medical Imaging
- Biomedical Engineering
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Pascal Tyrrell
Biomedical Engineering
1 shared papers, latest 2017
Pascal Tyrrell
Department of Medical Imaging
1 shared papers, latest 2017
Michael Glogauer
Dentistry
1 shared papers, latest 2012
Bernhard Ganss
Institute of Biomaterials and Biomedical Engineering
1 shared papers, latest 2017
Janet Rossant
Faculty
1 shared papers, latest 2011
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