Faculty profile

Janet Rossant

ResearcherUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Janet Rossant

Researcher

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
18 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 7 research grants (7 CIHR), most recently in 2014.
Supervised 3 trainees who won CIHR awards, most recently in 2010.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

146

Publications

515

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Blastocyst Cell Signaling Cystic Fibrosis Lung Development Mouse Development Mouse Genetics Reprogramming Single Cell Analysis

Latest papers

Human stem cell-based embryo models: innovation, ethics, and policy.
Human reproduction (Oxford, England) · 2026
Reply: Stem cell-based embryo models: scientific promise clashes with ethical reality.
Human reproduction (Oxford, England) · 2026
Author Correction: A comprehensive human embryo reference tool using single-cell RNA-sequencing data.
Nature methods · 2025

All 146 publications

Latest funding

Making the blastocyst; from lineage specification to stem cells to stem cell therapies
CIHR · 2014 · Nominated PI
$3,369,935
NSERC CREATE in Manufacturing, Materials and Mimetics (M3)
NSERC · 2013 · Co-investigator
$1,650,000
30th Annual Great Lakes Mammalian Development Meeting
CIHR · 2010 · Nominated PI
$5,000

All 14 grants and awards

146 publications.

Human stem cell-based embryo models: innovation, ethics, and policy.

Arias AM, Rivron N, Tajbakhsh S, Johnston J, Alev C, Bally-Cuif L, Böke E, Cavazza T, Cave E, Cyranoski D, David L, Esteban MA, Fu J, Geijsen N, de Graeff N, Hanna JH, Hopwood N, Inamdar MS, Lanner F, Leeners B, Liu Z, Jean Leon M, Minchiotti G, Moris N, Munsie M, Niakan KK, Pourquie O, Pasque V, Pera M, Peng Y, Petropoulos S, Ramanathan S, Rossant J, Rugg-Gunn P, Saitou M, Sermon K, Silva J, Theunissen T, Turco M, Wallingford J, Wang H, Warmflash A, Wu J, Yu L

Human reproduction (Oxford, England)2026

DOI: 10.1093/humrep/deag035 PMID: 41875051

Reply: Stem cell-based embryo models: scientific promise clashes with ethical reality.

Martinez Arias A, Rivron N, Tajbakhsh S, Johnston J, Alev C, Bally-Cuif L, Böke E, Cavazza T, Cave E, Cyranoski D, David L, Esteban MA, Fu J, Geijsen N, De Graeff N, Hanna JH, Hopwood N, Inamdar MS, Lanner F, Leeners B, Liu Z, Maitre JL, Minchiotti G, Moris N, Munsie M, Niakan KK, Pourquie O, Pasque V, Pera M, Peng Y, Petropoulos S, Ramanathan S, Rossant J, Rugg-Gunn P, Saitou M, Sermon K, Silva J, Theunissen T, Turco M, Wallingford J, Wang H, Warmflash A, Wu J, Yu L

Human reproduction (Oxford, England)2026

DOI: 10.1093/humrep/deag113 PMID: 42449529

Author Correction: A comprehensive human embryo reference tool using single-cell RNA-sequencing data.

Zhao C, Plaza Reyes A, Schell JP, Weltner J, Ortega NM, Zheng Y, Björklund ÅK, Baqué-Vidal L, Sokka J, Trokovic R, Cox B, Rossant J, Fu J, Petropoulos S, Lanner F

Nature methods2025

DOI: 10.1038/s41592-025-02601-w PMID: 39856235

Stem cell-based embryo models: The 2021 ISSCR stem cell guidelines revisited.

Clark AT, Cook-Andersen H, Franklin S, Isasi R, Mathews DJH, Pasque V, Rugg-Gunn PJ, Tam PPL, Wang H, Zylicz JJ, Rossant J

Stem cell reports2025Senior author

DOI: 10.1016/j.stemcr.2025.102514 PMID: 40499509

A comprehensive human embryo reference tool using single-cell RNA-sequencing data.

Zhao C, Plaza Reyes A, Schell JP, Weltner J, Ortega NM, Zheng Y, Björklund ÅK, Baqué-Vidal L, Sokka J, Trokovic R, Cox B, Rossant J, Fu J, Petropoulos S, Lanner F

Nature methods2025

DOI: 10.1038/s41592-024-02493-2 PMID: 39543283

An Irak1-Mecp2 tandem duplication mouse model for the study of MECP2 duplication syndrome.

Maino E, Scott O, Rizvi SZ, Chan WS, Visuvanathan S, Zablah YB, Li H, Sengar AS, Salter MW, Jia Z, Rossant J, Cohn RD, Gu B, Ivakine EA

Disease models & mechanisms2024

DOI: 10.1242/dmm.050528 PMID: 38881329

A fibronectin gradient remodels mixed-phase mesoderm.

Zhu M, Gu B, Thomas EC, Huang Y, Kim YK, Tao H, Yung TM, Chen X, Zhang K, Woolaver EK, Nevin MR, Huang X, Winklbauer R, Rossant J, Sun Y, Hopyan S

Science advances2024

DOI: 10.1126/sciadv.adl6366 PMID: 39028807

Why study human embryo development?

Rossant J

Developmental biology2024First author

DOI: 10.1016/j.ydbio.2024.02.001 PMID: 38325560

Author Correction: Changing the public perception of human embryology.

Rivron NC, Martinez-Arias A, Sermon K, Mummery C, Schöler HR, Wells J, Nichols J, Hadjantonakis AK, Lancaster MA, Moris N, Fu J, Sturmey RG, Niakan K, Rossant J, Kato K

Nature cell biology2023

DOI: 10.1038/s41556-023-01319-1 PMID: 38012405

Changing the public perception of human embryology.

Rivron NC, Martinez-Arias A, Sermon K, Mummery C, Schöler HR, Wells J, Nichols J, Hadjantonakis AK, Lancaster MA, Moris N, Fu J, Sturmey RG, Niakan K, Rossant J, Kato K

Nature cell biology2023

DOI: 10.1038/s41556-023-01289-4 PMID: 37985870

Making the blastocyst; from lineage specification to stem cells to stem cell therapies

Nominated PICIHR2014Foundation Grant

Principal investigators: Rossant, Janet

Keywords: Blastocyst; Cell Signaling; Cystic Fibrosis; Lung Development; Mouse Development; Mouse Genetics; Reprogramming; Single Cell Analysis; Stem Cells; Trophoblast

$3,369,935

NSERC CREATE in Manufacturing, Materials and Mimetics (M3)

Co-investigatorNSERC2013Collaborative Research and Training Experience

Principal investigators: Shoichet, Molly

$1,650,000

30th Annual Great Lakes Mammalian Development Meeting

Nominated PICIHR2010Meetings, Planning and Dissemination Grant: Genetics

Principal investigators: Rossant, Janet

Keywords: Cell Biology; Genetics; Graduate Students And Postdocs; Mammalian Development; Scientific And Social Interaction

$5,000

Transcriptional networks in trophoblast stem cell development

Nominated PICIHR2010Operating Grant

Principal investigators: Rossant, Janet

Keywords: Enhancer Activity; Gene Regulation; Stem Cell; Transcription Factor; Transcriptional Networks; Trophoblast

$1,049,389

Sox17-Mediated Regulation of Mammalian Endoderm Development

SupervisorCIHR2010Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Mcdonald, Angela C

Keywords: Bioinformatics; Definitive Endoderm; Embryonic Stem Cells; Enhancers; Epiblast Stem Cells; Extraembryonic Endoderm; Gene Regulation; Genomics; Molecular Biology; Pluripotent Stem Cells

$105,000

30th Annual Great Lakes Mammalian Development Meeting

Nominated PICIHR2009Meetings, Planning and Dissemination Grant: Genetics

Principal investigators: Rossant, Janet

Keywords: Graduate Students And Postdocs; Mammalian Development; Scientific And Social Interaction

$4,000

Uncovering Molecular Pathways Regulating Lung Epithelial Differentiation

SupervisorCIHR2009Fellowship - PA: Respiratory Health - CIHR/CLA/GSK

Principal investigators: Bilodeau, Mélanie

Keywords: Cell Sorting; Chip-Seq; Embryonic Stem Cells; Epitope Tagging; Fluorescent Reporter Gene; In Vitro Differentiation; Lung Epithelium; Mouse Model; Protein Complex Purification; Transcription Factor

$22,500

Genetic analysis of signaling pathways for vascular development and tumorigenesis

Principal investigatorCIHR2009Team Grant: Terry Fox New Frontiers Program in Cancer (LOI)

Principal investigators: Nagy, Andras; Ding, Hao; Pawson, Anthony J; Puri, Mira C; Quaggin, Susan E; Rossant, Janet; Wrana, Jeffrey L

Keywords: Intra- And Inter-Cell Signaling; Metastasis; Signal Transduction; Tumourigenesis; Vasculogenesis

Investigating the role of Hippo signaling in trophectoderm and inner cell mass specification

SupervisorCIHR2009Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Cockburn, Katherine J

Keywords: Cell-Cell Contact; Confocal Imaging; Gene Targeting; Hippo Signaling; Lineage Specification; Mouse Model; Preimplantation Development

$105,000

Lineage development in the mouse blastocyst

Nominated PICIHR2009Operating Grant

Principal investigators: Rossant, Janet

Keywords: Cell Lineage Specification; Embryo Development; Gene Regulation; Lineage Tracing; Pluripotency; Stem Cell Identity

$1,012,210

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Janet Rossant

Research

Latest papers

Latest funding

Human stem cell-based embryo models: innovation, ethics, and policy.

Reply: Stem cell-based embryo models: scientific promise clashes with ethical reality.

Author Correction: A comprehensive human embryo reference tool using single-cell RNA-sequencing data.

Stem cell-based embryo models: The 2021 ISSCR stem cell guidelines revisited.

A comprehensive human embryo reference tool using single-cell RNA-sequencing data.

An Irak1-Mecp2 tandem duplication mouse model for the study of MECP2 duplication syndrome.

A fibronectin gradient remodels mixed-phase mesoderm.

Why study human embryo development?

Author Correction: Changing the public perception of human embryology.

Changing the public perception of human embryology.

NSERC CREATE in Manufacturing, Materials and Mimetics (M3)

Frequent collaborators

Andras Nagy

Brian Cox

Thomas Kislinger

Felix Ratjen

Sophie Petropoulos

Igor Jurisica

Daniel Dufort

Martin Post

James Ellis

Lucy Osborne

Tanja Gonska

Yu Sun

Chen Wang

Sevan Hopyan

Marc Grynpas

Andrew Emili

Chi-Chung Hui

Derek van der Kooy

Xi Huang

Zhengping Jia

Augusto Zani

Denis Daneman

Myriam Hemberger

Yojiro Yamanaka

Wei Wang

Ahmed Aman

Pingzhao Hu

Jason Moffat

Irina Voronov

Peter Backx

Jonathan Kimmelman

Ubaka Ogbogu

Mick Bhatia

Jeremy Hirota

Nicholas Bock

Nicole Anderson