Jeffrey Henderson, University of Toronto

Research

Read how they describe their research on their University of Toronto profile.

Molecular neuroscience Biophysical chemistry Genetic programming Pharmacology and pharmaceutical sciences, n.e.c.

Latest papers

Antiretroviral drug dolutegravir induces inflammation at the mouse brain barriers.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
Biocompatible and bioactivable terpolymer-lipid-MnO2 Nanoparticle-based MRI contrast agent for improving tumor detection and delineation.
Materials today. Bio · 2024
Role of anti-inflammatory compounds in human immunodeficiency virus-1 glycoprotein120-mediated brain inflammation.
Journal of neuroinflammation · 2014

All 4 publications

Latest funding

Multitargeted Nanomedicine of Synergistic Drug Combinations for Metastatic Breast Cancer Therapy
CIHR · 2019 · Co-investigator
$501,076
Engineering Transformable Polymer-lipid Nanoparticles for Cascade Drug Delivery to Brain Cancer Cells
CIHR · 2014 · Co-investigator
$512,205
Analysis of FADD-dependent regulation of programmed cell death
NSERC · 2012 · Principal investigator
$130,000

All 5 grants and awards

4 publications.

01

Antiretroviral drug dolutegravir induces inflammation at the mouse brain barriers.

Huang C, Hoque MT, Qu QR, Henderson J, Bendayan R

FASEB journal : official publication of the Federation of American Societies for Experimental Biology2024

DOI: 10.1096/fj.202400558r PMID: 38982638

02

Biocompatible and bioactivable terpolymer-lipid-MnO2 Nanoparticle-based MRI contrast agent for improving tumor detection and delineation.

Yen TC, Abbasi AZ, He C, Lip HY, Park E, Amini MA, Adissu HA, Foltz W, Rauth AM, Henderson J, Wu XY

Materials today. Bio2024

DOI: 10.1016/j.mtbio.2024.100954 PMID: 38304342

03

Role of anti-inflammatory compounds in human immunodeficiency virus-1 glycoprotein120-mediated brain inflammation.

Ashraf T, Jiang W, Hoque MT, Henderson J, Wu C, Bendayan R

Journal of neuroinflammation2014

DOI: 10.1186/1742-2094-11-91 PMID: 24884548

04

Genomic analysis of induced pluripotent stem (iPS) cells: routes to reprogramming.

Kanawaty A, Henderson J

BioEssays : news and reviews in molecular, cellular and developmental biology2009Senior author

DOI: 10.1002/bies.200800204 PMID: 19204985

Multitargeted Nanomedicine of Synergistic Drug Combinations for Metastatic Breast Cancer Therapy

Co-investigatorCIHR2019Project Grant

Principal investigators: Wu, Xiao Yu S

Keywords: Blood-Brain Barrier Penetrating Nanoparticles; Cd44 Targeting; Integrin Targeting; Invasion And Migration; Metastatic Breast Cancer; Multitargeted Nanomedicine; Synergistic Drug Combination; Targeting Cd44 Pathways

$501,076

Engineering Transformable Polymer-lipid Nanoparticles for Cascade Drug Delivery to Brain Cancer Cells

Co-investigatorCIHR2014Operating Grant

Principal investigators: Wu, Xiao Yu S

Keywords: Anticancer Efficacy; Brain Metastases Of Cancer; Cascade Cancer Cell Targeting; Crossing The Blood-Brain Barrier; In Situe Changes Of Particle Size And Shape; In Vivo And In Vitro Imaging; Intracellular Distribution Of Nanoparticles; Polymer And Lipid Composition And Nanostructure; Transformable Nanoparticles; Whole Body And Brain Distribution

$512,205

Analysis of FADD-dependent regulation of programmed cell death

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Henderson, Jeffrey

$130,000

Free radical determinants of neurodegenerative disease

Co-investigatorCIHR2011Operating Grant

Principal investigators: Wells, Peter G

Keywords: Antioxidative Enzymes; Free Radicals; Neurodegeneration; Oxidative Dna Damage; Reactive Oxygen Species

$632,576

CIHR team in developmental toxicology

Co-investigatorCIHR2008Team Grant: Environment and Reproductive Health (LOI)

Principal investigators: Wells, Peter G

Keywords: Developmental Toxicology; Endocrine Disruptors; Environmental Contaminants; Epigenetics; Genetics; Oxidative Stress

$10,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Pharmaceutical Sciences
Department of Medicine
Other

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Reina Bendayan

Pharmaceutical Sciences

2 shared papers, latest 2024

Warren Foltz

Department of Medicine

1 shared papers, latest 2024

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Subject: Prospective PhD student: Molecular neuroscience Dear Professor Henderson, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Antiretroviral drug dolutegravir induces inflammation at the mouse brain barriers." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]