Faculty profile

Joanne Kotsopoulos

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ProfessorEpidemiology DivisionUniversity of Toronto

Joanne Kotsopoulos

Professor

Epidemiology Division

Dalla Lana School of Public Health

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
49 publications in the last five years, latest in 2026.
Senior (last) author on 18 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (10 CIHR), most recently in 2026.
Supervised 3 trainees who won CIHR awards, most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

139

Publications

1,552

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Screening Breast Cancer Survival Treatment Observational Administrative Data Biomarkers Cancer

Latest papers

Urinary arsenic levels and risk of breast cancer among women in the Canadian health measures survey: a population-based prospective study.
Environmental research · 2026 · senior author
Germline ATRIP variants and the risk of ovarian cancer.
Genetics in medicine : official journal of the American College of Medical Genetics · 2026
Projected Benefit of Bilateral Salpingo-Oophorectomy by Age in BRCA Carriers.
JAMA surgery · 2026

All 139 publications

Latest funding

Evaluating Outcomes after Risk-reducing Oophorectomy in BRCA carriers
CIHR · 2026 · Principal investigator
$647,356
Establishing a Global Cohort to Investigate ATRIP-Associated Cancer Risk and Outcomes
CIHR · 2025 · Co-investigator
$1,044,225
Treatment of Ductal Carcinoma In-Situ in Women with a BRCA1 or BRCA2 Pathogenic Variant
CIHR · 2024 · Nominated PI
$699,976

All 20 grants and awards

139 publications.

Urinary arsenic levels and risk of breast cancer among women in the Canadian health measures survey: a population-based prospective study.

Pullella K, Chang VC, Giannakeas V, Lubiński J, Harris SA, Hanley AJ, Narod SA, Kotsopoulos J

Environmental research2026Senior author

DOI: 10.1016/j.envres.2026.123791 PMID: 41581689

Germline ATRIP variants and the risk of ovarian cancer.

Zamani N, Wokołorczyk D, Kluźniak W, Ogrodniczak A, Jakubowska A, Chahal M, Stempa K, Gliniewicz K, Huzarski T, Rudnicka H, Szwiec M, Stawicka M, Kaznowska E, Kluz T, Domagała P, Dębniak T, McLaughlin J, Lubiński J, Gronwald J, Narod SA, Kotsopoulos J, Cybulski C, Akbari MR

Genetics in medicine : official journal of the American College of Medical Genetics2026

DOI: 10.1016/j.gim.2026.102547 PMID: 42118082

Projected Benefit of Bilateral Salpingo-Oophorectomy by Age in BRCA Carriers.

Giannakeas V, Apostol AI, Diella C, Dave N, Gronwald J, Fruscio R, Karlan BY, Cybulski C, Singer CF, Møller P, Kim RH, Bordeleau L, Ramón Y Cajal T, Pal T, Eisen A, Couch FJ, Zakalik D, Metcalfe K, Tung N, Aeilts A, Sun P, Lubinski J, Kotsopoulos J, Narod SA, Hereditary Ovarian Cancer Clinical Study Group

JAMA surgery2026

DOI: 10.1001/jamasurg.2026.4356 PMID: 42776544

Rethinking Menopausal Hormone Therapy After Risk-Reducing Salpingo-Oophorectomy in Women at High Risk for Breast Cancer.

Wong SM, Kotsopoulos J

Obstetrics and gynecology2026Senior author

DOI: 10.1097/aog.0000000000006429 PMID: 42743437

Menopausal hormone therapy and the risk of breast cancer in women with a pathogenic variant in BRCA1 or BRCA2

Kotsopoulos J, Seca M, Gronwald J, Huzarski T, Møller P, Kim RH, Singer CF, Karlan B, Aeilts A, Ramón y Cajal T

Journal of the National Cancer Institute202611 citationsFirst author

DOI: 10.1093/jnci/djaf363

Risk of Breast Cancer After Ovarian Cancer in Women With a Pathogenic/Likely Pathogenic Variant in BRCA1 or BRCA2

Apostol AI, Gronwald J, Cybulski C, Kim RH, Møller P, Karlan BY, Bordeleau L, Schrader I, Ramón y Cajal T, Pal T

Journal of Clinical Oncology20265 citationsSenior author

DOI: 10.1200/jco-25-01648

The use of menopause hormone therapy in borderline ovarian tumor survivors: a systematic review and meta-analysis

Mejia-Gomez J, Tigert M, Jacobson M, Shprits E, Shea AK, Philippopoulos E, Kotsopoulos J, Bridger A, Diaz NS, Puveendrakumaran P

Climacteric2026

DOI: 10.1080/13697137.2026.2675561

Endometrial thickness among BRCA mutation carriers undergoing prophylactic oophorectomy.

Jacobson M, Klejnotowska A, Sun P, Narod SA, Kotsopoulos J

Familial cancer2025Senior author

DOI: 10.1007/s10689-025-00458-8 PMID: 40131523

Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in BRCA1 and BRCA2

Phillips K-A, Kotsopoulos J, Domchek SM, Terry MB, Chamberlain JA, Bassett JK, Aeilts AM, Andrulis IL, Buys SS, Cui W

Journal of Clinical Oncology202524 citations

DOI: 10.1200/jco.24.00176

The incidence of pancreatic cancer in women with a BRCA1 or BRCA2 mutation

Katona BW, Lubinski J, Pal T, Huzarski T, Foulkes WD, Moller P, Eisen A, Armel SR, Neuhausen SL, Raj R

Cancer202515 citations

DOI: 10.1002/cncr.35666

Evaluating Outcomes after Risk-reducing Oophorectomy in BRCA carriers

Principal investigatorCIHR2026Project Grant

Principal investigators: Narod, Steven A; Kotsopoulos, Joanne; Metcalfe, Kelly A

Keywords: Breast Cancer; Menopausal Hormonal Therapy; Patient Reported Outcomes; Preventive Surgery; Survival; Treatment

$647,356

Establishing a Global Cohort to Investigate ATRIP-Associated Cancer Risk and Outcomes

Co-investigatorCIHR2025Project Grant

Principal investigators: Akbari, Mohammad Reza

Keywords: Atrip; Breast Cancer,; Cancer Risk; Hereditary Cancer; Prognosis; Tumour Profile

$1,044,225

Treatment of Ductal Carcinoma In-Situ in Women with a BRCA1 or BRCA2 Pathogenic Variant

Nominated PICIHR2024Project Grant

Principal investigators: Kotsopoulos, Joanne; Metcalfe, Kelly A

Keywords: Brca1; Brca2; Ductal Carcinoma In Situ (Dcis); Genetic Testing; Health Outcomes; Invasive Breast Cancer; Observational; Surgery; Survival; Treatment

$699,976

A Low-Cost Accessible Smart Platform for Determination of Homologous Recombination Deficiency (HRD) in Ovarian Tumours Using Routine Histology Slides

Co-investigatorSSHRC2024New Frontiers in Research Fund - Exploration

Principal investigators: Akbari, Mohammad Reza

$125,000

Optimizing Cancer Prediction in Ontario: Leveraging Electronic Health Data and Machine Learning for Early Detection

Nominated PICIHR2023Project Grant - Priority Announcement: Early Detection/Cancer Prevention

Principal investigators: Kotsopoulos, Joanne

Keywords: Administrative Data; Biomarkers; Cancer; Early Detection; Health Services; Health Visualization; Machine Learning; Ontario; Routine Blood Work; Screening

$100,000

An observational study of treatment and outcomes among BRCA1 carriers with breast cancer

Co-investigatorCIHR2023Project Grant

Principal investigators: Narod, Steven A

Keywords: Brca1; Breast Cancer; Male Breast Cancer; Survival

$765,000

Optimizing Cancer Prediction in Ontario: Leveraging Electronic Medical Records and Machine Learning for Early Detection

Nominated PICIHR2023Project Grant - Priority Announcement: Early Detection/Cancer Prevention

Principal investigators: Kotsopoulos, Joanne

Keywords: Administrative Data; Biomarkers; Brca; Cancer; Complete Blood Counts; Health Services; Machine Learning; Observational; Platelets; Screening

$100,000

Canada Research Chair - Tier 2

Nominated PICIHR2022Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Kotsopoulos, Joanne

Keywords: Crc

$500,000

Delineating the relationship between arsenic exposure and cancer risk

SupervisorCIHR2021Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Pullella, Katherine

Keywords: Arsenic; Biomarkers; Canadian Cancer Registry; Canadian Health Measures Survey; Cancer; Environmental Health; Heavy Metals; Population Health; Predictors; Risk

$105,000

Evaluating the relationship between circulating osteoprotegerin levels and bone mineral density in BRCA mutation carriers

SupervisorCIHR2019Undergraduate: Summer Studentship Award - Institute Community Support

Principal investigators: Hall, Elizabeth S

Keywords: Bone Mineral Density; Brca Mutation Carriers; Breast Cancer; Osteopenia; Osteoporosis; Osteoprotegerin (Opg); Receptor Activator Of Nuclear Factor Kappa-¿ Ligand (Rankl)

$5,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on July 30, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Joanne Kotsopoulos

Research

Latest papers

Latest funding

Urinary arsenic levels and risk of breast cancer among women in the Canadian health measures survey: a population-based prospective study.

Germline ATRIP variants and the risk of ovarian cancer.

Projected Benefit of Bilateral Salpingo-Oophorectomy by Age in BRCA Carriers.

Rethinking Menopausal Hormone Therapy After Risk-Reducing Salpingo-Oophorectomy in Women at High Risk for Breast Cancer.

Menopausal hormone therapy and the risk of breast cancer in women with a pathogenic variant in BRCA1 or BRCA2

Risk of Breast Cancer After Ovarian Cancer in Women With a Pathogenic/Likely Pathogenic Variant in BRCA1 or BRCA2

The use of menopause hormone therapy in borderline ovarian tumor survivors: a systematic review and meta-analysis

Endometrial thickness among BRCA mutation carriers undergoing prophylactic oophorectomy.

Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Mutations in BRCA1 and BRCA2

The incidence of pancreatic cancer in women with a BRCA1 or BRCA2 mutation

A Low-Cost Accessible Smart Platform for Determination of Homologous Recombination Deficiency (HRD) in Ovarian Tumours Using Routine Histology Slides

Frequent collaborators

Andrea Eisen

Andrea Eisen

Louise Bordeleau

Kelly Metcalfe

Barry Rosen

Vasily Giannakeas

Leonardo Salmena

Young-In Kim

Steven Narod

Joanne Kotsopoulos

Michelle Cotterchio

Ophira Ginsburg

Igor Jurisica

William Foulkes

Lorraine Lipscombe

Wendy Wolfman

Ahmed El-Sohemy

Laura Rosella

Martin Yaffe

Dalia Barsyte-Lovejoy

Angela Cheung

Jacob McGee

An-Wen Chan

Angela Cheung

Razqallah Hakem

Jennifer Brooks

Raymond Kim

Neil Fleshner

Maureen Trudeau

Rama Khokha

Andrea Jurisicova

Alison Shea