Faculty profile
John Semple
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Read how they describe their research on their University of Toronto profile.
Latest papers
Core competencies for healthcare practitioners and clinics providing gender-affirming care from the patient perspective: An international qualitative study
Journal of Plastic, Reconstructive and Aesthetic Surgery · 2025
International study to develop a patient-reported outcome measure to evaluate outcomes of gender-affirming care - the GENDER-Q
Journal of Patient-Reported Outcomes · 2024
Health state utility values in patients undergoing chest masculinization surgery
Journal of Plastic, Reconstructive and Aesthetic Surgery · 2023
Latest funding
- $199,965
BEFORE (Begin Exploring Fertility Options, Risks and Expectations): a novel Canadian e-health app to facilitate shared decision-making for people at risk of cancer treatment related infertility.
CIHR · 2017 · Co-investigator
Identification of host cellular immune mechanisms responsible for the initiation and/or modulation of Transfusion Related Acute Lung Injury (TRALI).
CIHR · 2015 · Nominated PI
Mechanisms of antibody-independent transfusion-related acute lung injury (TRALI)
CIHR · 2014 · Co-investigator
21 publications.
Core competencies for healthcare practitioners and clinics providing gender-affirming care from the patient perspective: An international qualitative study
Kaur MN, Morrison SD, Kennedy SL, van de Grift TC, Højgaard A, Jacobsen AL, Johnson N, Mullender MG, Poulsen L, Satterwhite T
International study to develop a patient-reported outcome measure to evaluate outcomes of gender-affirming care - the GENDER-Q
Kaur MN, Morrison SD, Kennedy SL, van de Grift TC, Højgaard A, Jacobsen AL, Johnson N, Mullender MG, Poulsen L, Satterwhite T
Health state utility values in patients undergoing chest masculinization surgery
Kaur MN, Gallo L, Wang Y, Rae C, McEvenue G, Semple J, Johnson N, Savard K, Pusic AL, Coon D
The BODY-Q Chest Module: Further Validation in a Canadian Chest Masculinization Surgery Sample
Klassen AF, McEvenue G, Wang Y, Rae C, Kaur M, Johnson N, Savard K, Semple J, Pusic A
Too Deep or Not Too Deep?: A Propensity-Matched Comparison of the Analgesic Effects of a Superficial Versus Deep Serratus Fascial Plane Block for Ambulatory Breast Cancer Surgery.
Abdallah FW, Cil T, MacLean D, Madjdpour C, Escallon J, Semple J, Brull R
International phase I study protocol to develop a patient-reported outcome measure for adolescents and adults receiving gender-affirming treatments (the GENDER-Q)
Klassen AF, Kaur M, Johnson N, Kreukels BP, McEvenue G, Morrison SD, Mullender MG, Poulsen L, Ozer M, Rowe W
Mobile Web-Based Follow-up for Postoperative ACL Reconstruction: A Single-Center Experience.
Higgins J, Semple J, Murnaghan L, Sharpe S, Theodoropoulos J
Breast Cancer Genetics for Plastic Surgeons.
McInerney NM, Narod S, Metcalfe K, Semple J, Brown MH
Why Some Mastectomy Patients Opt to Undergo Delayed Breast Reconstruction: Results of a Long-Term Prospective Study.
Metcalfe KA, Semple J, Quan ML, Holloway C, Wright F, Narod S, Hofer S, Bagher S, Zhong T
Erratum to: The Multi Centre Canadian Acellular Dermal Matrix Trial (MCCAT): study protocol for a randomized controlled trial in implant-based breast reconstruction.
Zhong T, Temple-Oberle C, Hofer SO, Beber B, Semple J, Brown M, Macadam S, Lennox P, Panzarella T, McCarthy C, Baxter N, MCCAT Study Group
BEFORE (Begin Exploring Fertility Options, Risks and Expectations): a novel Canadian e-health app to facilitate shared decision-making for people at risk of cancer treatment related infertility.
Principal investigators: Baxter, Nancy N
Keywords: Cancer; Decision Support Tools; Fertility Preservation; Health Behaviour Change; Health Services Research; Oncofertility; Qualitative Research; Shared Decision-Making; Treatment-Related Infertility; Young Adult
Identification of host cellular immune mechanisms responsible for the initiation and/or modulation of Transfusion Related Acute Lung Injury (TRALI).
Principal investigators: Semple, John W
Keywords: Chemokine Blockade; Cytokines/Chemokines; Hypovolemia; Microparticles; Monocytes; Neutrophils; Platelets; Recipient Immune Factors; Transfusion Related Acute Lung Injury
Mechanisms of antibody-independent transfusion-related acute lung injury (TRALI)
Principal investigators: Kuebler, Wolfgang M
Keywords: Acute Lung Injury; Intravital Microscopy; Microparticles; Mouse Model; Platelet Storage; Sphingolipids; Transfusion-Related Acute Lung Injury
Development of a National Quality Improvement Program in Postmastectomy Breast Reconstruction to Optimize Patient-Centred Experience.
Principal investigators: Zhong, Toni
Keywords: Clinical Trials; Cost-Effectiveness Analysis; Knowledge Dissemination And Translation; Patient-Reported Outcomes; Population-Based Health Services Research; Postmastectomy Breast Reconstruction; Randomized Controlled Trials; Shared-Decision Making And Support; Supportive Care; Surgical Techniques; Survivorship Quality Of Life
Understanding host mechanisms responsible for immune platelet destruction and thrombocytopenia.
Principal investigators: Semple, John W
Keywords: Cd61; Immune Thrombocytopenia (Itp); Mhc Class I; Platelet Antibodies; Platelet Destruction; Platelet Refractoriness
Replacing ambulatory clinic follow-up with remote home monitoring using smartphones in breast reconstruction patients: Is it cost-effective?
Principal investigators: Semple, John L; Bhatia, Rajan S
Keywords: Ambulatory Surgical Procedures; Breast Reconstruction; Cost-Effectiveness; Health Services Research; Telemedicine
Identification of host immune factors responsible for the initiation and/or modulation of Transfusion Related Acute Lung Injury (TRALI).
Principal investigators: Semple, John W
Keywords: Cytokine/Chemokines; Intravenous Gammaglobulin; Macrophages; Neutrophils; Platelets; Recipient Immune Factors; T Cells; Transfusion Related Acute Lung Injury
The Canadian Regenerative Medicine Network (CRM-Net) / Le Réseau Canadien de Médecine Régénérative
Principal investigators: Sefton, Michael
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pediatrics
- Department of Surgery
- Plastic Surgery
- Department of Pharmacology and Toxicology
- Institute of Health Policy
- Epidemiology Division
- Biostatistics Division
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Natasha Johnson
Pediatrics
5 shared papers, latest 2025
Anne Klassen
Pediatrics
5 shared papers, latest 2025
Toni Zhong
Department of Surgery
4 shared papers, latest 2017
Mitchell Brown
Department of Surgery
2 shared papers, latest 2016
Tony Panzarella
Biostatistics Division
2 shared papers, latest 2016
Nancy Baxter
Institute of Health Policy
2 shared papers, latest 2016
Stefan Hofer
Plastic Surgery
2 shared papers, latest 2017
Steven Narod
Epidemiology Division
2 shared papers, latest 2017
Frances Wright
Faculty
1 shared papers, latest 2017
David Wasserstein
Orthopedics and Rehabilitation
1 shared papers, latest 2013
Tulin Cil
Surgery
1 shared papers, latest 2018
Kelly Metcalfe
Plastic Surgery
1 shared papers, latest 2017
Shinya Ito
Internal Medicine
1 shared papers, latest 2006
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.