Kevin Truong, University of Toronto

Research

apoptosis calcium signaling gene expression magnetogenetics protein engineering synthetic biology

Latest papers

Prompt-Only Gene-Circuit Modeling with a Large Language Model Simulates the synNotch Spheroids.
ACS synthetic biology · 2026 · senior author
Estimating genotype-tissue specific gene expression using hybrid deep learning.
Communications biology · 2026 · senior author
Optimal solution to the set cover problem with a vicinity constraint for estimating genotype tissue expression profiles.
Bioinformatics advances · 2025 · senior author

All 56 publications

Latest funding

Genetically encoded tools to control any mammalian cell function with any desired stimulus
NSERC · 2019 · Principal investigator
$252,000
Elucidating `design' principles for engineering synthetic protein networks
NSERC · 2014 · Principal investigator
$125,000
Computational algorithms for genomic functional annotation
NSERC · 2005 · Principal investigator
$54,000

All 3 grants and awards

56 publications.

01

Prompt-Only Gene-Circuit Modeling with a Large Language Model Simulates the synNotch Spheroids.

Chen K, Truong K

ACS synthetic biology2026Senior author

DOI: 10.1021/acssynbio.5c00704 PMID: 41968604

02

Estimating genotype-tissue specific gene expression using hybrid deep learning.

Dong J, Brown S, Truong K

Communications biology2026Senior author

DOI: 10.1038/s42003-026-10251-7 PMID: 42129502

03

Optimal solution to the set cover problem with a vicinity constraint for estimating genotype tissue expression profiles.

Dong J, Brown S, Truong K

Bioinformatics advances2025Senior author

DOI: 10.1093/bioadv/vbaf163 PMID: 40746507

04

Nearby and non-nested genes in the human genome have more similar genotype tissue expression.

Dong J, Brown S, Truong K

PloS one2024Senior author

DOI: 10.1371/journal.pone.0307360 PMID: 39292702

05

On the Precise Link between Energy and Information.

Witkowski C, Brown S, Truong K

Entropy (Basel, Switzerland)2024Senior author

DOI: 10.3390/e26030203 PMID: 38539715

06

Engineering a synthesis-friendly serum responsive promoter for antibiotic selection of genomic integration in cell-based therapy.

Lam CKC, Truong K

Biotechnology letters2022Senior author

DOI: 10.1007/s10529-022-03244-z PMID: 35294696

07

Design of Synthetic Mammalian Promoters Using Highly Palindromic Subsequences.

Govorkova P, Candice Lam CK, Truong K

ACS synthetic biology2022Senior author

DOI: 10.1021/acssynbio.1c00600 PMID: 35225601

08

Design of a synthesis-friendly hypoxia-responsive promoter for cell-based therapeutics.

Lam CKC, Truong K

Engineering in life sciences2021Senior author

DOI: 10.1002/elsc.202100045 PMID: 34899121

09

Generation of stable cell lines using readthrough expression from lentiviral integration.

Jadav A, Truong K

Biotechnology letters2021Senior author

DOI: 10.1007/s10529-021-03186-y PMID: 34533680

10

Creation of a synthesis-friendly inflammation-inducible promoter suitable for cell therapy.

Jadav A, Truong K

Integrative biology : quantitative biosciences from nano to macro2021Senior author

DOI: 10.1093/intbio/zyab015 PMID: 34632498

Genetically encoded tools to control any mammalian cell function with any desired stimulus

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Truong, Kevin

Keywords: apoptosis; calcium signaling; gene expression; magnetogenetics; protein engineering; synthetic biology

$252,000

Elucidating `design' principles for engineering synthetic protein networks

Principal investigatorNSERC2014Discovery Grants Program - Individual

Principal investigators: Truong, Kevin

$125,000

Computational algorithms for genomic functional annotation

Principal investigatorNSERC2005Discovery Grants Program - Individual

Principal investigators: Truong, Kevin

$54,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biomaterials and Biomedical Engineering, Inst. of (IBBME)
Department of Anesthesiology and Pain Medicine
Research

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Stephen Brown

Department of Anesthesiology and Pain Medicine

4 shared papers, latest 2026

Mitsuhiko Ikura

Research

1 shared papers, latest 2007

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2019

Subject: Prospective PhD student: apoptosis Dear Professor Truong, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Prompt-Only Gene-Circuit Modeling with a Large Language Model Simulates the synNotch Spheroids." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Genetically encoded tools to control any mammalian cell function with any desired stimulus" (2019), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]