Faculty profile

Keyvan Karkouti

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ProfessorDepartment of Anesthesiology and Pain MedicineUniversity of Toronto

Keyvan Karkouti

Professor

Department of Anesthesiology and Pain Medicine

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Scholar ORCID

Supervision signals

Professors usually supervise graduate students in their department's programs.
55 publications in the last five years, latest in 2026.
Senior (last) author on 13 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2025.
Supervised 1 trainee who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

144

Publications

2,633

Citations

h-index

123

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Education

M.D.
M.Sc. in Clinical Epidemiology and Health Care Research, Health Administration

Profiles and links

University Profile Google Scholar iDORCID

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Osteoarthritis Pain Randomized Controlled Trial Cardiac Surgery Persistent Pain Prevention Total Knee Arthroplasty Vitamin C

Latest papers

Perioperative Antithrombin Activity and Postoperative Outcomes in Adult Cardiac Surgery: A Prospective Cohort in Contemporary Plasma-Sparing Practice.
Journal of cardiothoracic and vascular anesthesia · 2026
Preoperative Iron-Deficiency Anemia and Survival After Cardiac Surgery: A Retrospective Cohort Study.
Journal of cardiothoracic and vascular anesthesia · 2026
Serial Ketamine Infusions for Treatment-Resistant Bipolar Depression: A Randomized Clinical Trial.
JAMA psychiatry · 2026

All 144 publications

Latest funding

Optimizing perioperative blood management and patient recovery in cardiac surgery
CIHR · 2025 · Supervisor
$120,000
Perioperative Vitamin C to reduce persistent pain after total knee arthroplasty (PROVISION): a multicentre randomized controlled trial
CIHR · 2025 · Principal investigator
$100,000
Combining Ketamine with Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals with Treatment Resistant Depression and Borderline Personality Disorder: A Phase II Randomized, Midazolam-Controlled Clinical Trial
CIHR · 2024 · Co-investigator
$1,362,848

All 13 grants and awards

144 publications.

Perioperative Antithrombin Activity and Postoperative Outcomes in Adult Cardiac Surgery: A Prospective Cohort in Contemporary Plasma-Sparing Practice.

Hua N, Abraha M, Guerra REG, Barkley V, Callum J, Payne D, Lieberman L, McCluskey SA, Karkouti K, Bartoszko J

Journal of cardiothoracic and vascular anesthesia2026

DOI: 10.1053/j.jvca.2026.08.157 PMID: 42786025

Preoperative Iron-Deficiency Anemia and Survival After Cardiac Surgery: A Retrospective Cohort Study.

Alkadri J, Chen M, Karkouti K, Grudzinski A, Ouzounian M, Rubens F, Raphael J, Callum J, Lin Y, McCluskey SA, McIsaac DI, Bartoszko J

Journal of cardiothoracic and vascular anesthesia2026

DOI: 10.1053/j.jvca.2026.04.018 PMID: 42091376

Serial Ketamine Infusions for Treatment-Resistant Bipolar Depression: A Randomized Clinical Trial.

Orsini DK, Di Luch S, Tomlinson G, Lovell GFM, Vasudeva S, Rodrigues NB, Johnson DE, Flint AJ, Llach CD, McIntyre RS, Mansur RB, Karkouti K, Burhan AM, Kaczmarek E, Chisamore N, Bhatia A, Soneji N, Joshi A, Grewal D, Laframboise R, Rosenblat JD

JAMA psychiatry2026

DOI: 10.1001/jamapsychiatry.2026.2658 PMID: 42684694

Association of Preoperative Echocardiographic Right Ventricular Systolic Function With Outcomes After Cardiac Surgery: A Retrospective Cohort Study.

Alavi N, Bartoszko J, Karkouti K, Wijeysundera HC, Chung J, Mathis MR, Mashari A, Salvatori M, Vegas A, Van Klei W

Anesthesia and analgesia2026

DOI: 10.1213/ane.0000000000007931 PMID: 42607294

The association of estimated citrate load with frozen plasma versus four-factor prothrombin complex concentrate for coagulopathy after cardiac surgery: a post hoc exploratory analysis of the FARES-II randomised controlled trial.

Tanaka KA, Butt AL, Stewart KE, Pezeshki G, Werner S, Bartoszko J, Ghadimi K, Solomon C, Vandyck K, Levy JH, Callum JL, Knaub S, Hegener O, Karkouti K

BJA open2026Senior author

DOI: 10.1016/j.bjao.2026.100577 PMID: 42404094

Use of Factor Concentrates for the Management of Perioperative Bleeding: Guidance from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis.

Levy JH, Shaw JR, Siegal DM, Callum J, Frere C, Karkouti K, Maier CL, Mazzeffi M, Samama CM, Shorr R, Tanaka KA, Dyke CM, Connors JM

Journal of thrombosis and haemostasis : JTH2026

DOI: 10.1016/j.jtha.2026.07.030 PMID: 42665231

Factor Concentrates for the Treatment of Acquired Coagulopathy in Patients With Left Ventricular Assist Devices: A Systematic Review.

Kojundzic I, Lam A, Holmes M, Dvirnik N, Janda A, Petricevic M, Englesakis M, Karkouti K, Bartoszko J

Journal of cardiothoracic and vascular anesthesia2026

DOI: 10.1053/j.jvca.2026.08.120 PMID: 42674901

Postoperative anaemia and long-term survival following cardiac surgery: a multicentre, retrospective, observational study.

Boyko Y, Lindhardt RB, Chen M, Bartozko J, Andersen CL, Juhl-Olsen P, Karkouti K, Ravn HB, Rasmussen SB

Anaesthesia2026

DOI: 10.1111/anae.70306 PMID: 42478340

Superiority of Fibrinogen Concentrate Versus Cryoprecipitate for Treatment of Bleeding in Cardiac Surgery Patients: A Secondary Analysis of the FIBRES Randomized Clinical Trial Stratified by Surgical Risk.

Bartoszko J, Karkouti K, Callum JL, FIBRES Research Group

Journal of cardiothoracic and vascular anesthesia2026

DOI: 10.1053/j.jvca.2026.06.019 PMID: 42448488

Predictors and prognostic value for in-hospital outcomes associated with postoperative anemia in cardiac surgery: a retrospective cohort study.

Chen MMZ, Ouzounian M, McCluskey S, Karkouti K, Bartoszko J

Canadian journal of anaesthesia = Journal canadien d'anesthesie2026

DOI: 10.1007/s12630-026-03126-2 PMID: 42174358

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Osteoarthritis Dear Professor Karkouti, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Perioperative Antithrombin Activity and Postoperative Outcomes in Adult Cardiac Surgery: A Prospective Cohort in Contemporary Plasma-Sparing Practice." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Perioperative Vitamin C to reduce persistent pain after total knee arthroplasty (PROVISION): a multicentre randomized controlled trial" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

Something wrong or missing on this profile? Suggest a correction

Keyvan Karkouti

Research

Latest papers

Latest funding

Perioperative Antithrombin Activity and Postoperative Outcomes in Adult Cardiac Surgery: A Prospective Cohort in Contemporary Plasma-Sparing Practice.

Preoperative Iron-Deficiency Anemia and Survival After Cardiac Surgery: A Retrospective Cohort Study.

Serial Ketamine Infusions for Treatment-Resistant Bipolar Depression: A Randomized Clinical Trial.

Association of Preoperative Echocardiographic Right Ventricular Systolic Function With Outcomes After Cardiac Surgery: A Retrospective Cohort Study.

The association of estimated citrate load with frozen plasma versus four-factor prothrombin complex concentrate for coagulopathy after cardiac surgery: a post hoc exploratory analysis of the FARES-II randomised controlled trial.

Use of Factor Concentrates for the Management of Perioperative Bleeding: Guidance from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis.

Factor Concentrates for the Treatment of Acquired Coagulopathy in Patients With Left Ventricular Assist Devices: A Systematic Review.

Postoperative anaemia and long-term survival following cardiac surgery: a multicentre, retrospective, observational study.

Superiority of Fibrinogen Concentrate Versus Cryoprecipitate for Treatment of Bleeding in Cardiac Surgery Patients: A Secondary Analysis of the FIBRES Randomized Clinical Trial Stratified by Surgical Risk.

Predictors and prognostic value for in-hospital outcomes associated with postoperative anemia in cardiac surgery: a retrospective cohort study.

Frequent collaborators

Justyna Bartoszko

Jeannie Callum

Jeannie Callum

Mark Crowther

Summer Syed

Hance Clarke

Marcin Wasowicz

Duminda Wijeysundera

Daniel Santa Mina

Michelle Zeller

Corey Sawchuk

Peter Lawrence Gross

George Tomlinson

Lusine Abrahamyan

Sheila Riazi

Paul Yip

Christopher Harle

David Mazer

Nancy Heddle

Diem Tran

Venkat Bhat

Jamie Robertson

Marcus Salvatori

Ruxandra Pinto

Wilton van Klei

Nicholas Mitsakakis

Christine Cserti-Gazdewich

Norman Buckley

Donald Arnold

James Paul

Andre Lamy

Michael Law

Paul Engels

Michael Murphy

Ryan Zarychanski

Alexis Turgeon

Shaf Keshavjee

Navdeep Tangri

Anand Govindarajan

Shabbir Alibhai