Faculty profile

Christopher Harle

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Associate ProfessorDepartment of Anesthesia & Perioperative MedicineWestern University

Christopher Harle

Associate Professor

Department of Anesthesia & Perioperative Medicine

Schulich School of Medicine & Dentistry

Western University

London, Ontario, Canada

Supervision signals

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5 publications in the last five years, latest in 2026.

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Academic metrics

Publications

255

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Research

Read how they describe their research on their Western University profile.

Latest papers

Efficacy of Erector Spinae Block on Postoperative Outcomes in Bariatric Surgery Patients: A Systematic Review, Meta-Regression, and Trial-Sequential Analysis of Randomized Controlled Trials.
Obesity surgery · 2026
Comparison between the Fibrinogen Clauss Assay and the TEG6S Citrated Functional Fibrinogen in Cardiac Surgery.
Journal of cardiothoracic and vascular anesthesia · 2026
Use of prothrombin complex concentrates in liver transplantation: a systematic review and meta-analysis.
British journal of anaesthesia · 2025

All 15 publications

Latest funding

Bleeding Reduction in Acute and Chronic KidnEy patienTs having Surgery - Vanguard Phase
CIHR · 2024 · Co-investigator
$130,050
Cognitive Outcomes after Dexmedetomidine sedation in Cardiac Surgery: CODEX RCT
CIHR · 2024 · Co-investigator
$2,620,125
Four-Factor Prothrombin Complex Concentrate Versus Frozen Plasma in Bleeding Adult Cardiac Surgical Patients: A multicentre randomized controlled trial
CIHR · 2021 · Co-investigator
$1,082,474

All 3 grants and awards

15 publications.

Efficacy of Erector Spinae Block on Postoperative Outcomes in Bariatric Surgery Patients: A Systematic Review, Meta-Regression, and Trial-Sequential Analysis of Randomized Controlled Trials.

Voznyy V, Abu Al-Burak S, Subramani Y, Elganga M, Iansavitchene A, Fochesato LA, Singh P, Williams H, Harle C, Nagappa M

Obesity surgery2026

DOI: 10.1007/s11695-026-08716-z PMID: 42096123

Comparison between the Fibrinogen Clauss Assay and the TEG6S Citrated Functional Fibrinogen in Cardiac Surgery.

Alfred T, da Costa LGV, Harle C, Zamper R

Journal of cardiothoracic and vascular anesthesia2026

DOI: 10.1053/j.jvca.2025.08.022 PMID: 40954002

Use of prothrombin complex concentrates in liver transplantation: a systematic review and meta-analysis.

Kojundzic I, Alavi N, Lam A, Karkouti K, Callum J, Bieze M, Luzzi C, Shwaartz C, Englesakis M, Carrier FM, Boldingh JW, Vos JJ, van den Berg JP, Görlinger K, Harle C, Carr A, Lisman T, van Klei WA, McCluskey SA, Bartoszko J

British journal of anaesthesia2025

DOI: 10.1016/j.bja.2025.07.079 PMID: 40945996

Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery

Karkouti K, Callum JL, Bartoszko J, Tanaka KA, Knaub S, Brar S, Ghadimi K, Rochon A, Mullane D, Couture EJ

Journal of the American Medical Association (JAMA)202563 citations

DOI: 10.1001/jama.2025.3501

Hospital policy of tranexamic acid to reduce transfusion in major non-cardiac surgery (TRACTION): protocol for a phase IV randomised controlled trial.

Houston BL, McIsaac DI, Breau RH, Andrews M, Avramescu S, Bagry H, Balshaw RF, Daya J, Duncan K, Harle C, Jacobsohn E, Kerelska T, McIsaac S, Ramsay T, Saha T, Perelman I, Recio A, Solvason D, Szoke D, Tenenbein M, Fergusson DA, Zarychanski R

BMJ open2024

DOI: 10.1136/bmjopen-2024-084847 PMID: 38830735

Magnetic resonance imaging-guided transurethral ultrasound ablation in patients with localised prostate cancer: 3-year outcomes of a prospective Phase I study.

Nair SM, Hatiboglu G, Relle J, Hetou K, Hafron J, Harle C, Kassam Z, Staruch R, Burtnyk M, Bonekamp D, Schlemmer HP, Roethke MC, Mueller-Wolf M, Pahernik S, Chin JL

BJU international2021

DOI: 10.1111/bju.15268 PMID: 33037765

As clear as mud: new evidence regarding transfusion triggers in cardiac surgery.

Harle C, Chong MA

Canadian journal of anaesthesia = Journal canadien d'anesthesie2020First author

DOI: 10.1007/s12630-020-01593-9 PMID: 32189215

Hybrid Coronary Revascularization Versus Off-Pump Coronary Artery Bypass Grafting: Comparative Effectiveness Analysis With Long-Term Follow-up.

Hage A, Giambruno V, Jones P, Chu MW, Fox S, Teefy P, Lavi S, Bainbridge D, Harle C, Iglesias I, Dobkowski W, Kiaii B

Journal of the American Heart Association2019

DOI: 10.1161/jaha.119.014204 PMID: 31826727

Rescue Balloon Aortic Valvuloplasty After Sutureless Aortic Valve Replacement for Severe Paravalvular Leak.

Nagaoka E, Sato K, Hage A, Bagur R, Harle C, Asopa S, Kiaii B

Innovations (Philadelphia, Pa.)2019

DOI: 10.1177/1556984519864938 PMID: 31570026

Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery

Callum J, Farkouh ME, Scales DC, Heddle NM, Crowther M, Rao V, Hucke H-P, Carroll J, Grewal D, Brar S

Journal of the American Medical Association (JAMA)2019192 citationsOpen Access

DOI: 10.1001/jama.2019.17312 PMID: W2980819145

Profile data last refreshed on November 9, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Christopher Harle

Research

Latest papers

Latest funding

Efficacy of Erector Spinae Block on Postoperative Outcomes in Bariatric Surgery Patients: A Systematic Review, Meta-Regression, and Trial-Sequential Analysis of Randomized Controlled Trials.

Comparison between the Fibrinogen Clauss Assay and the TEG6S Citrated Functional Fibrinogen in Cardiac Surgery.

Use of prothrombin complex concentrates in liver transplantation: a systematic review and meta-analysis.

Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery

Hospital policy of tranexamic acid to reduce transfusion in major non-cardiac surgery (TRACTION): protocol for a phase IV randomised controlled trial.

Magnetic resonance imaging-guided transurethral ultrasound ablation in patients with localised prostate cancer: 3-year outcomes of a prospective Phase I study.

As clear as mud: new evidence regarding transfusion triggers in cardiac surgery.

Hybrid Coronary Revascularization Versus Off-Pump Coronary Artery Bypass Grafting: Comparative Effectiveness Analysis With Long-Term Follow-up.

Rescue Balloon Aortic Valvuloplasty After Sutureless Aortic Valve Replacement for Severe Paravalvular Leak.

Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery

Bleeding Reduction in Acute and Chronic KidnEy patienTs having Surgery - Vanguard Phase

Cognitive Outcomes after Dexmedetomidine sedation in Cardiac Surgery: CODEX RCT

Four-Factor Prothrombin Complex Concentrate Versus Frozen Plasma in Bleeding Adult Cardiac Surgical Patients: A multicentre randomized controlled trial

Frequent collaborators

Rodrigo Bagur

Keyvan Karkouti

Summer Syed

Michelle Zeller

Jeannie Callum

Justyna Bartoszko

Ivan Iglesias

Mahesh Nagappa

Yamini Subramani

Raffael Zamper

Michael Law

Mark Crowther

Daniel Bainbridge

Jeannie Callum

Achal Dhir

Diem Tran

Miguel Arango

Nancy Heddle

Ryan Zarychanski