Faculty profile

Mike Seed

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Associate ProfessorDepartment of PhysiologyUniversity of Toronto

Mike Seed

Associate Professor

Department of Physiology

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
100 publications in the last five years, latest in 2026.
Senior (last) author on 26 recent papers, a sign of leading a research group.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

331

Publications

5,923

Citations

100

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Extracardiac conduit restriction is associated with increased liver fibrosis in adolescent Fontan patients.
The Journal of thoracic and cardiovascular surgery · 2026
Prevalence of Ischemic Brain Injury in Neonates With Congenital Heart Disease: A Systematic Review and Meta-Analysis.
Neurology · 2026
Maternal late gestation undernutrition in sheep is associated with increased ductus venosus shunting and reduced cerebral oxygen consumption.
The Journal of physiology · 2026

All 331 publications

Latest funding

The Artificial Placenta - Sustaining Extrauterine Fetal Circulation in the Extremely Premature.
SSHRC · 2021 · Co-investigator
$250,000
Advanced Fetal Diagnosis and Therapy Program
CFI · 2020 · Co-investigator
$2,845,545
Toronto Perinatal Brain Protection Research Collaboration
CFI · 2017 · Co-investigator
$937,305

All 3 grants and awards

From the 150 most recent of 331 publications.

Extracardiac conduit restriction is associated with increased liver fibrosis in adolescent Fontan patients.

Ponzoni M, Saleh J, Chaturvedi RR, Dipchand AI, Valverde I, Seed M, Yoo SJ, Coles J, Honjo O, Lam CZ

The Journal of thoracic and cardiovascular surgery20262 citations

DOI: 10.1016/j.jtcvs.2025.09.044 PMID: 41047073

Prevalence of Ischemic Brain Injury in Neonates With Congenital Heart Disease: A Systematic Review and Meta-Analysis.

Kim C, Chetan D, Kazazian V, Alzamil J, Chau V, Seed M, Miller SP, Selvanathan T

Neurology20261 citations

DOI: 10.1212/wnl.0000000000214569 PMID: 41512205

Maternal late gestation undernutrition in sheep is associated with increased ductus venosus shunting and reduced cerebral oxygen consumption.

Cho SKS, Saini BS, Darby JRT, Holman SL, Lock MC, Williams GK, Perumal R, Macgowan C, Seed M, Morrison JL

The Journal of physiology20261 citationsOpen Access

DOI: 10.1113/jp288413 PMID: 41493396

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, S. H. Cho, C. F. MacGowan, M. J. Seed, Manuel Wiese, Janna L. Morrison

The Journal of Physiology20261 citationsOpen Access

DOI: 10.1113/jp289670 PMID: 41811217

BRIGHT pathways: recommendations to improve the developmental follow-up of children with CHD in Canada - protocol for a nominal group study.

Bolduc ME, Saini BS, Patey AM, Sadiku E, Miller SP, Simard MN, Brossard-Racine M, Majnemer A, Ly LG, Sananes R, Seed M

BMJ open20261 citationsSenior authorOpen Access

DOI: 10.1136/bmjopen-2026-116425 PMID: 42463189

Role of α-adrenergic activation during the hemodynamic response to maternal hyperoxygenation in fetal sheep

Jordan A. Minns, Jack R. T. Darby, Steven K. S. Cho, Brahmdeep S. Saini, Stacey L. Holman, Christopher K Macgowan, Mike Seed, Janna Leigh Morrison

Biology of Reproduction2026Open Access

DOI: 10.1093/biolre/ioag165 PMID: 42550489

Preoperative Hemodynamics and Brain Injury in Transposition of the Great Arteries.

Chetan D, Selvanathan T, Lee FT, Smaili H, Bao M, Lim JM, Marini D, Saini A, Peyvandi S, McQuillen P, Branson HM, Chau V, Miller SP, Seed M

JACC. Advances2026Senior authorOpen Access

DOI: 10.1016/j.jacadv.2026.102592 PMID: 41906606

miR-15b inhibition induces cardiac proliferation and supresses immune response after myocardial infarction without improving cardiac function

Mitchell C. Lock, Steven Cho, Catherine G. Dimasi, Jack R. T. Darby, Stacey L. Holman, Joseph Selvanayagam, Christopher K. Macgowan, Mike Seed, Janna Leigh Morrison

Journal of Molecular and Cellular Cardiology Plus2026Open Access

DOI: 10.1016/j.jmccpl.2025.100616

Cerebral Blood Flow and Neurodevelopment in Congenital Heart Disease

Jessie Mei Lim, Davide Marini, Amandeep Saini, Stephanie H. Au‐Young, Alejandro Floh, Thiviya Selvanathan, Anna Tedesco-Bruce, Louise Bannister, Erika Gibson, Rebekah Kjerland Jobling, Rajiv R Chaturvedi, Raymond H. Kim, Marisa Signorile, Kyle Runeckles, Ting Guo, Alison Howell, Liqun Sun, John C. Kingdom, Linh Gia Ly, Vann Chau, Renée Sananes, Steven P. Miller, Mike Seed

Neurology Open Access2026Senior authorOpen Access

DOI: 10.1212/wn9.0000000000000098

Automated reconstruction of dynamic 2D fetal cardiac MRI using deep learning in late third-trimester fetuses

William Myers, Datta Singh Goolaub, Mike Seed, Christopher K. Macgowan

European Journal of Radiology2026

DOI: 10.1016/j.ejrad.2026.113197 PMID: 42700702

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Mike Seed

Research

Latest papers

Latest funding

Extracardiac conduit restriction is associated with increased liver fibrosis in adolescent Fontan patients.

Prevalence of Ischemic Brain Injury in Neonates With Congenital Heart Disease: A Systematic Review and Meta-Analysis.

Maternal late gestation undernutrition in sheep is associated with increased ductus venosus shunting and reduced cerebral oxygen consumption.

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

BRIGHT pathways: recommendations to improve the developmental follow-up of children with CHD in Canada - protocol for a nominal group study.

Role of α-adrenergic activation during the hemodynamic response to maternal hyperoxygenation in fetal sheep

Preoperative Hemodynamics and Brain Injury in Transposition of the Great Arteries.

miR-15b inhibition induces cardiac proliferation and supresses immune response after myocardial infarction without improving cardiac function

Cerebral Blood Flow and Neurodevelopment in Congenital Heart Disease

Automated reconstruction of dynamic 2D fetal cardiac MRI using deep learning in late third-trimester fetuses

The Artificial Placenta - Sustaining Extrauterine Fetal Circulation in the Extremely Premature.

Advanced Fetal Diagnosis and Therapy Program

Toronto Perinatal Brain Protection Research Collaboration

Frequent collaborators

Michael Seed

Christopher Macgowan

Janna Morrison

Shi-Joon Yoo

Edgar Jaeggi

John Kingdom

Steven Miller

John Sled

Vann Chau

Christoph Haller

Davide Marini

Cedric Manlhiot

Luc Mertens

Lindsay Cahill

Thiviya Selvanathan

Osami Honjo

Anne Dipchand

Dafna Sussman

Mark McVey

David Barron

Rachel Wald

Greg Ryan

Andreea Dragulescu

Conall Morgan

Birgit Ertl-Wagner

Rory Windrim

Linh Ly

Archana Rai

Andrea Wan

Edmond Kelly

Barbara CIfra

Prakash Muthusami

Johannes Keunen

Lindsay Freud

Carolina Gorodetsky

A Guerguerian

Vitor Guerra

Brian McCrindle

Aamir Jeewa

Jennifer Russell