Neil Goldenberg, University of Toronto

Research

Read how they describe their research on their University of Toronto profile.

Pulmonary Hypertension Systemic Sclerosis Cytoskeleton Endothelial Cell Spectrin Fibrillin Fibroblast Hmgb1

Latest papers

Association Between Cyanosis, Transfusion, and Thrombotic Complications in Neonates and Children Undergoing Cardiac Surgery.
Journal of cardiothoracic and vascular anesthesia · 2020
Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury.
American journal of respiratory cell and molecular biology · 2016
The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4
Biochemical Journal · 2009

All 3 publications

Latest funding

Inhibition of Spectrin Breakdown to Prevent Endothelial Dysfunction in Pulmonary Arterial Hypertension
CIHR · 2026 · Nominated PI
$1,005,976
Mechanism of activation and therapeutic targeting of lytic cell death in pulmonary arterial hypertension
CIHR · 2024 · Co-investigator
$875,926
Targeting Inflammation in Pulmonary Arterial Hypertension: The Importance of Gasdermin D
CIHR · 2022 · Supervisor
$105,000

All 5 grants and awards

3 publications.

01

Association Between Cyanosis, Transfusion, and Thrombotic Complications in Neonates and Children Undergoing Cardiac Surgery.

Ali U, Goldenberg N, Foreman C, Crawford Lynn L, Honjo O, O'Leary J, Faraoni D

Journal of cardiothoracic and vascular anesthesia2020

DOI: 10.1053/j.jvca.2019.07.123 PMID: 31399304

02

Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury.

Yin J, Michalick L, Tang C, Tabuchi A, Goldenberg N, Dan Q, Awwad K, Wang L, Erfinanda L, Nouailles G, Witzenrath M, Vogelzang A, Lv L, Lee WL, Zhang H, Rotstein O, Kapus A, Szaszi K, Fleming I, Liedtke WB, Kuppe H, Kuebler WM

American journal of respiratory cell and molecular biology2016

DOI: 10.1165/rcmb.2014-0225oc PMID: 26222277

03

The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4

Plant PJ, Correa J, Goldenberg N, Bain J, Batt J

Biochemical Journal200921 citations

DOI: 10.1042/bj20081866

Inhibition of Spectrin Breakdown to Prevent Endothelial Dysfunction in Pulmonary Arterial Hypertension

Nominated PICIHR2026Project Grant

Principal investigators: Goldenberg, Neil M

Keywords: Cytoskeleton; Endothelial Cell; Pulmonary Hypertension; Spectrin

$1,005,976

Mechanism of activation and therapeutic targeting of lytic cell death in pulmonary arterial hypertension

Co-investigatorCIHR2024Project Grant

Principal investigators: Steinberg, Benjamin E

Keywords: Immune Cells; Inflammation; Lytic Cell Death; Pulmonary Hypertension; Pyroptosis

$875,926

Targeting Inflammation in Pulmonary Arterial Hypertension: The Importance of Gasdermin D

SupervisorCIHR2022Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Foley, Anna E

Keywords: Gasdermin D; Hypoxia; Il-1b; Inflammasome; Innate Immunity; Pulmonary Arterial Hypertension; Pulmonary Vasculature; Right Ventricle

$105,000

Targeting Danger Signals In Systemic Sclerosis-Associated Pulmonary Arterial Hypertension

Nominated PICIHR2021Project Grant

Principal investigators: Goldenberg, Neil M

Keywords: Fibrillin; Fibroblast; Hmgb1; Pulmonary Circulation; Pulmonary Hypertension; Pulmonary Vascular; Systemic Sclerosis; Tgf-Beta

$830,025

Immunological Dysfunction in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension

Nominated PICIHR2019CLA/CIHR-ICRH/AZ Canada Emerging Clinician Scientist Award

Principal investigators: Goldenberg, Neil M

Keywords: Hmgb; Inflammation; Pulmonary Hypertension; Systemic Sclerosis; Vascular Remodeling

$147,232

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Surgery
Department of Anesthesiology and Pain Medicine
Department of Surgery
Anesthesia
Medicine
Other

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

James Bain

Surgery

1 shared papers, latest 2009

Andras Kapus

Department of Surgery

1 shared papers, latest 2016

Jane Batt

Medicine

1 shared papers, latest 2009

Haibo Zhang

Anesthesia

1 shared papers, latest 2016

Katalin Szaszi

Faculty

1 shared papers, latest 2016

Ori Rotstein

Surgery

1 shared papers, latest 2016

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2026

Subject: Prospective PhD student: Pulmonary Hypertension Dear Professor Goldenberg, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Association Between Cyanosis, Transfusion, and Thrombotic Complications in Neonates and Children Undergoing Cardiac Surgery." (2020), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Inhibition of Spectrin Breakdown to Prevent Endothelial Dysfunction in Pulmonary Arterial Hypertension" (2026), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]