Faculty profile

Andras Kapus

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ProfessorDepartment of SurgeryUniversity of Toronto

Andras Kapus

Professor

Department of Surgery

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

ORCID

Supervision signals

Professors usually supervise graduate students in their department's programs.
10 publications in the last five years, latest in 2026.
Principal investigator on 12 research grants (6 CIHR, 6 NSERC), most recently in 2025.
Supervisor on 1 trainee award (1 CIHR), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

507

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Education

Post-doctorate
PhD
MD

Profiles and links

University Profile Personal Website Search on Google Scholar iDORCID

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Cytoskeleton Mutagenesis Protein-Protein Interactions Primary Cilium Mrtf Myofibroblast Transcription Factors Nuclear Import And Export

Latest papers

MRCKα Is a Suppressor of GEF-H1/RhoA/MRTF Signaling in Tubular Cells.
Cells · 2026
Mitochondrial Transplantation: A Novel Therapy for Liver Ischemia/Reperfusion Injury.
Annals of surgery · 2025
Left ventricular pressure-loading improves pressure-induced right ventricular remodeling by redistributing mechanical load and reducing mechanosignaling.
Physiological reports · 2025

All 52 publications

Latest funding

Mechanism and regulation of the nuclear transport and novel, non-transcriptional functions of TAZ/YAP
CIHR · 2025 · Nominated PI
$1,158,975
Myocardin Related Transcription Factor regulates primary cilium assembly: A new mechanism of relevance to fibrosis
CIHR · 2023 · Supervisor
$90,000
The Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Meeting and Investigator Summit
CIHR · 2022 · Co-investigator
$10,000

All 20 grants and awards

52 publications.

MRCKα Is a Suppressor of GEF-H1/RhoA/MRTF Signaling in Tubular Cells.

Sri Theivakadadcham VS, Dan Q, Wu B, Venugopal S, Maksimoska V, Yucel-Polat A, Kapus A, Szászi K

Cells2026

DOI: 10.3390/cells15050447 PMID: 41827880

Mitochondrial Transplantation: A Novel Therapy for Liver Ischemia/Reperfusion Injury.

Mukkala AN, David BA, Ailenberg M, Liang J, Vaswani CM, Karakas D, Goldfarb R, Barbour W, Gasner A, Wu RS, Petrut R, Jerkic M, Andreazza AC, Dos Santos C, Ni H, Zhang H, Kapus A, Kubes P, Rotstein OD

Annals of surgery2025

DOI: 10.1097/sla.0000000000006655 PMID: 39912224

Left ventricular pressure-loading improves pressure-induced right ventricular remodeling by redistributing mechanical load and reducing mechanosignaling.

Lee XA, Raschzok S, Desjardins JF, Van Loon T, Plavetic A, Kanny O, Kabir G, Nghiem L, Dauz J, Kapus A, Lumens J, Connelly KA, Friedberg MK

Physiological reports2025

DOI: 10.14814/phy2.70546 PMID: 40969144

SR3677 IS HEPATOPROTECTIVE IN MURINE LIVER ISCHEMIA/REPERFUSION INJURY: POTENTIAL ROLE OF BNIP3L/NIX (BCL2/ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3-LIKE).

Mukkala AN, Maksimoska V, Noble E, Ailenberg M, Petrut R, Goldfarb R, Kapus A, Szaszi K, Rotstein OD

Shock (Augusta, Ga.)2025

DOI: 10.1097/shk.0000000000002527 PMID: 39617401

Inhibition of Myocardin-related Transcription Factor A Ameliorates Pathological Remodeling of the Pressure-loaded Right Ventricle.

Rzepka MF, Raschzok S, Lee XA, Yazaki K, Dauz J, Sun M, Meister T, Nghiem L, Kabir G, Desjardins JF, Kuebler WM, Kapus A, Connelly KA, Friedberg MK

American journal of respiratory cell and molecular biology2025

DOI: 10.1165/rcmb.2023-0465oc PMID: 39163574

Augmented Parkin-dependent mitophagy underlies the hepatoprotective effect of remote ischemic conditioning used prior to hemorrhagic shock

Naraiah Mukkala A, Petrut R, Goldfarb R, Leigh Beroncal E, Ho Leung C, Khan Z, Ailenberg M, Jerkic M, Andreazza AC, Rhind SG

Mitochondrion202315 citations

DOI: 10.1016/j.mito.2023.03.002

Therapeutic Effects of Mesenchymal Stromal Cells Require Mitochondrial Transfer and Quality Control.

Mukkala AN, Jerkic M, Khan Z, Szaszi K, Kapus A, Rotstein O

International journal of molecular sciences2023

DOI: 10.3390/ijms242115788 PMID: 37958771

Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles.

Guo X, Khosraviani N, Raju S, Singh J, Farahani NZ, Abramian M, Torres VJ, Howe KL, Fish JE, Kapus A, Lee WL

Frontiers in immunology2023

DOI: 10.3389/fimmu.2023.1181016 PMID: 37153544

Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit

Burger D, Abdelrasoul A, Alexander RT, Ballermann B, Bridgewater D, Chan JSD, Cunanan J, Cybulsky AV, Gerarduzzi C, Gunaratnam L

Canadian Journal of Kidney Health and Disease2022

DOI: 10.1177/20543581221144824

DDR1 associates with TRPV4 in cell-matrix adhesions to enable calcium-regulated myosin activity and collagen compaction.

Wang AY, Coelho NM, Arora PD, Wang Y, Eymael D, Ji C, Wang Q, Lee W, Xu J, Kapus A, Carneiro KMM, McCulloch CA

Journal of cellular physiology2022

DOI: 10.1002/jcp.30696 PMID: 35150133

Mechanism and regulation of the nuclear transport and novel, non-transcriptional functions of TAZ/YAP

Nominated PICIHR2025Project Grant

Principal investigators: Kapus, Andras

Keywords: Mutagenesis; Nuclear Import And Export; Optogenetics; Protein-Protein Interactions; Quantitative Microscopy; Rho Gtpases; Spindle Assembly Checkpoint; Structure-Function Relationships; Taz/Yap Biology

$1,158,975

Myocardin Related Transcription Factor regulates primary cilium assembly: A new mechanism of relevance to fibrosis

SupervisorCIHR2023CIHR Fellowship

Principal investigators: Bennett, Henrietta W

Keywords: Biochemistry; Cell Cycle; Fibrosis; Live-Cell Microscopy; Organellar Biology; Primary Cilium; Protein-Protein Interactions; Super-Resolution Microscopy; Tissue Reprogramming; Transcription Factors

$90,000

The Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Meeting and Investigator Summit

Co-investigatorCIHR2022Planning and Dissemination Grant - Institute Community Support

Principal investigators: Torban, Elena

Keywords: Biomarkers; Canadian; Disease Models; Diversity; Genetics; Kidney; Kidney Injury; Knowledge Translation; Mechanisms Of Disease; Molecular Biology

$10,000

The role of myocardin-related transcription factor (MRTF) in polycystic kidney disease

Nominated PICIHR2021Project Grant

Principal investigators: Kapus, Andras

Keywords: Myocardin-Related Transcription Factor (Mrtf); Organ Fibrosis; Pathobiology; Polycystic Kidney Disease; Rho Signaling; Tubular Epithelium

$833,850

Characterization of a new class of nuclear localization signals

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Kapus, Andras

$348,000

Mitochondrial quality control during hemorrhagic shock: positive impact of remote ischemic conditioning.

Co-investigatorCIHR2018Project Grant

Principal investigators: Rotstein, Ori D

Keywords: Hemorrhagic Shock; Inflammation; Intervention; Ischemia Reperfusion; Liver Injury And Hepatoprotection; Macrophages; Mitophagy Proteins; Nrf2; Remote Ischemic Conditioning; Zebrafish

$627,300

Myocardin-related transcription factor (MRTF) and serum response factor (SRF) are constituents and key regulators of the primary cilium

Nominated PICIHR2018Project Grant

Principal investigators: Kapus, Andras

Keywords: Cell Biology; Ciliopathies; Cytoskeleton; Fluorescence Microscopy; Mutagenesis; Myocardin-Related Transcription Factor; Primary Cilium; Protein-Protein Interactions; Serum Response Factor; Transcriptional Regulation

$688,500

Bioreactors for biomechanical conditioning and evaluation of native and engineered tissues

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Simmons, Craig

$150,000

Mask aligner for a microfluidic soft lithography cleanroom

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Tsai, Scott

$148,447

Fast wavelength switching controls and a high sensitivity camera for enhanced imaging

Co-investigatorNSERC2016Research Tools and Instruments

Principal investigators: Fairn, Gregory

$89,081

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Andras Kapus

Research

Latest papers

Latest funding

MRCK&#x3b1; Is a Suppressor of GEF-H1/RhoA/MRTF Signaling in Tubular Cells.

Mitochondrial Transplantation: A Novel Therapy for Liver Ischemia/Reperfusion Injury.

Left ventricular pressure-loading improves pressure-induced right ventricular remodeling by redistributing mechanical load and reducing mechanosignaling.

SR3677 IS HEPATOPROTECTIVE IN MURINE LIVER ISCHEMIA/REPERFUSION INJURY: POTENTIAL ROLE OF BNIP3L/NIX (BCL2/ADENOVIRUS E1B 19 KDA PROTEIN-INTERACTING PROTEIN 3-LIKE).

Inhibition of Myocardin-related Transcription Factor A Ameliorates Pathological Remodeling of the Pressure-loaded Right Ventricle.

Augmented Parkin-dependent mitophagy underlies the hepatoprotective effect of remote ischemic conditioning used prior to hemorrhagic shock

Therapeutic Effects of Mesenchymal Stromal Cells Require Mitochondrial Transfer and Quality Control.

Endothelial ACKR1 is induced by neutrophil contact and down-regulated by secretion in extracellular vesicles.

Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit

DDR1 associates with TRPV4 in cell-matrix adhesions to enable calcium-regulated myosin activity and collagen compaction.

Mechanism and regulation of the nuclear transport and novel, non-transcriptional functions of TAZ/YAP

Myocardin Related Transcription Factor regulates primary cilium assembly: A new mechanism of relevance to fibrosis

The Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Meeting and Investigator Summit

The role of myocardin-related transcription factor (MRTF) in polycystic kidney disease

Characterization of a new class of nuclear localization signals

Mitochondrial quality control during hemorrhagic shock: positive impact of remote ischemic conditioning.

Myocardin-related transcription factor (MRTF) and serum response factor (SRF) are constituents and key regulators of the primary cilium

Bioreactors for biomechanical conditioning and evaluation of native and engineered tissues

Mask aligner for a microfluidic soft lithography cleanroom

Fast wavelength switching controls and a high sensitivity camera for enhanced imaging

Frequent collaborators

Katalin Szaszi

Sergio Grinstein

Ori Rotstein

Boris Hinz

Mingyao Liu

Haibo Zhang

Chung-Wai Chow

Sunny Hartwig

Andrew Advani

Burton Yang

Jane Batt

Steeve Provencher

Heyu Ni

Dylan Burger

Ran Kafri

Lakshman Gunaratnam

Julie Fradette

Casimiro Gerarduzzi

Barbara Ballermann

Neil Goldenberg

Xiao-Yan Wen

Leanne Stalker

Caroline Lamarche

Darren Bridgewater

Ahmad Sidiqi

Michael Glogauer

Robert Rottapel

Jennifer Tsang

Tomoko Takano

Claudia Dos Santos

Paul Kubes

Robert Inman

Burton Yang

Lori Burrows

Marc Jeschke

MRCKα Is a Suppressor of GEF-H1/RhoA/MRTF Signaling in Tubular Cells.