Faculty profile
Scott Heximer
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Read how they describe their research on their University of Toronto profile.
Latest papers
Apolipoprotein A-IV polymorphisms Q360H and T347S attenuate its endogenous inhibition of thrombosis.
Biochemical and biophysical research communications · 2024
B-Cell Deficiency Lowers Blood Pressure in Mice.
Hypertension (Dallas, Tex. : 1979) · 2019
Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2018
Latest funding
- $17,500
The Role of Regulator of G-protein Signaling 4 (RGS4) in Atrial Fibrillation
CIHR · 2012 · Supervisor
- $10,000
11th Annual Joint Meeting of the Great Lakes GPCR Retreat and le Club des Récepteurs à 7 TM
CIHR · 2010 · Principal investigator
- $688,548
Characterization of novel mechanisms underlying pathophysiologic remodeling of atrial myocytes during the genesis of atrial fibrillation.
CIHR · 2010 · Nominated PI
6 publications.
Apolipoprotein A-IV polymorphisms Q360H and T347S attenuate its endogenous inhibition of thrombosis.
MacKeigan DT, Yu SY, Chazot N, Zhang D, Khoury CJ, Lei X, Bhoria P, Shen C, Chen P, Zhu G, Rand ML, Heximer S, Ni H
B-Cell Deficiency Lowers Blood Pressure in Mice.
Dingwell LS, Shikatani EA, Besla R, Levy AS, Dinh DD, Momen A, Zhang H, Afroze T, Chen MB, Chiu F, Simmons CA, Billia F, Gommerman JL, John R, Heximer S, Scholey JW, Bolz SS, Robbins CS, Husain M
Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5.
Arnold C, Demirel E, Feldner A, Genové G, Zhang H, Sticht C, Wieland T, Hecker M, Heximer S, Korff T
Type VIII collagen mediates vessel wall remodeling after arterial injury and fibrous cap formation in atherosclerosis.
Lopes J, Adiguzel E, Gu S, Liu SL, Hou G, Heximer S, Assoian RK, Bendeck MP
Tumor necrosis factor-α-mediated downregulation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-1-phosphate signaling in a mouse model of heart failure.
Meissner A, Yang J, Kroetsch JT, Sauvé M, Dax H, Momen A, Noyan-Ashraf MH, Heximer S, Husain M, Lidington D, Bolz SS
c-Myb-dependent inositol 1,4,5-trisphosphate receptor type-1 expression in vascular smooth muscle cells.
Afroze T, Sadi AM, Momen MA, Gu S, Heximer S, Husain M
The Role of Regulator of G-protein Signaling 4 (RGS4) in Atrial Fibrillation
Principal investigators: Mighiu, Alexandra
Keywords: Electrophysiology Studies; In Vivo Intracardiac Studies; Optical Mapping
11th Annual Joint Meeting of the Great Lakes GPCR Retreat and le Club des Récepteurs à 7 TM
Principal investigators: Angers, Stephane; Hampson, David R; Heximer, Scott P; Wells, James W
Keywords: Cell Signalling; G Protein Coupled Receptors; Heterotrimeric G Proteins; Signal Transduction
Characterization of novel mechanisms underlying pathophysiologic remodeling of atrial myocytes during the genesis of atrial fibrillation.
Principal investigators: Heximer, Scott P
Keywords: Atrial Fibrillation; Atrial Myocyte; Girk Channel Regulation; Katp Channel Regulation; Parasympathetic Signaling; Regulator Of G-Protein Signaling
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Mansoor Husain and Scott Heximer: 3 shared papers
- Mansoor Husain and Filio Billia: 2 shared papers
- Mansoor Husain and Heyu Ni: 1 shared paper
- Filio Billia and Scott Heximer: 1 shared paper
- Heyu Ni and Scott Heximer: 1 shared paper
- Department of Physiology
- Medicine
- Physiology
- Laboratory Medicine & Pathobiology
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.