Faculty profile
Sergey Plotnikov
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Research
Latest papers
A tale of two distinct actin networks underlies the entire life cycle of focal adhesion.
bioRxiv : the preprint server for biology · 2025
A Noisy Analog-to-Digital Converter Connects Cytosolic Calcium Bursts to Transcription Factor Nuclear Localization Pulses in Yeast.
G3 (Bethesda, Md.) · 2019
Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo.
Cell reports · 2018
Latest funding
- $726,750
Molecular analysis of cell migration through control of the physical microenvironment
CIHR · 2021 · Nominated PI
- $192,000
Biophysical control of cell migration by mechanical gradients in cell microenvironment
NSERC · 2020 · Principal investigator
- $707,625
Control of matrix remodeling through an actin binding protein
CIHR · 2016 · Co-investigator
4 publications.
A tale of two distinct actin networks underlies the entire life cycle of focal adhesion.
Dong R, Ishii K, Plotnikov S, Liu J
A Noisy Analog-to-Digital Converter Connects Cytosolic Calcium Bursts to Transcription Factor Nuclear Localization Pulses in Yeast.
Hsu IS, Strome B, Plotnikov S, Moses AM
Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo.
Haage A, Goodwin K, Whitewood A, Camp D, Bogutz A, Turner CT, Granville DJ, Lefebvre L, Plotnikov S, Goult BT, Tanentzapf G
A ternary complex comprising FAK, PTPα and IP3 receptor 1 functionally engages focal adhesions and the endoplasmic reticulum to mediate IL-1-induced Ca2+ signalling in fibroblasts.
Wang Q, Wang Y, Downey GP, Plotnikov S, McCulloch CA
Molecular analysis of cell migration through control of the physical microenvironment
Principal investigators: Plotnikov, Sergey V; McCulloch, Christopher A
Keywords: Biomechanics; Cell Adhesion; Cell Migration; Cytoskeleton; Durotaxis; Extracellular Matrix; Focal Adhesions; Mechanosensing; Mechanotransduction; Traction Force Microscopy
Biophysical control of cell migration by mechanical gradients in cell microenvironment
Principal investigators: Plotnikov, Sergey
Control of matrix remodeling through an actin binding protein
Principal investigators: McCulloch, Christopher A
Keywords: Actin; Actin Binding Proteins; Cell Adhesions; Collagen; Extracellular Matrix; Filamin; Integrins; Periodontal Diseases; Phagocytosis; Protein Degradation
Regulation of cell migration by biochemical and mechanical environmental cues
Principal investigators: Plotnikov, Sergey
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Guy Tanentzapf and Louis Lefebvre: 2 shared papers
- Guy Tanentzapf and Sergey Plotnikov: 1 shared paper
- Louis Lefebvre and Sergey Plotnikov: 1 shared paper
- Cell and Systems Biology
- Cellular and Physiological Sciences
- Medical Genetics
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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