Bruce Reed, University of Waterloo

Research

CRISPR/Cas9 genome editing EGFR/RAS/MAPK signaling genetic screens programmed cell death transcriptional regulation

Latest papers

20-hydroxyecdysone (20E) signaling regulates amnioserosa morphogenesis during Drosophila dorsal closure: EcR modulates gene expression in a complex with the AP-1 subunit, Jun.
Biology open · 2021
Overexpression of hindsight in sensory organ precursors is associated with a transformation of campaniform sensilla to microchaetae in the Drosophila wing.
microPublication biology · 2019 · senior author
Studying Nonproliferative Roles for Egfr Signaling in Tissue Morphogenesis Using Dorsal Closure of the Drosophila Embryo.
Methods in molecular biology (Clifton, N.J.) · 2017 · first author

All 3 publications

Latest funding

Investigating the role of the transcription factor Hindsight in the regulation of EGFR/Ras/MAPK signaling: new applications for CRISPR/Cas9 genome editing
NSERC · 2020 · Principal investigator
$180,000
Investigating the function of Hindsight/RREB-1 in the intestinal stem cell lineage of Drosophila
NSERC · 2015 · Principal investigator
$190,000
The genetic analysis of autophagy-dependent caspase activity in drosophila
NSERC · 2010 · Principal investigator
$135,000

All 9 grants and awards

3 publications.

01

20-hydroxyecdysone (20E) signaling regulates amnioserosa morphogenesis during Drosophila dorsal closure: EcR modulates gene expression in a complex with the AP-1 subunit, Jun.

Yoo B, Kim HY, Chen X, Shen W, Jang JS, Stein SN, Cormier O, Pereira L, Shih CRY, Krieger C, Reed B, Harden N, Wang SJH

Biology open2021

DOI: 10.1242/bio.058605 PMID: 34296248

02

Overexpression of hindsight in sensory organ precursors is associated with a transformation of campaniform sensilla to microchaetae in the Drosophila wing.

Szablewski K, Reed B

microPublication biology2019Senior author

DOI: 10.17912/micropub.biology.000103 PMID: 32550447

03

Studying Nonproliferative Roles for Egfr Signaling in Tissue Morphogenesis Using Dorsal Closure of the Drosophila Embryo.

Reed B, Harden N

Methods in molecular biology (Clifton, N.J.)2017First author

DOI: 10.1007/978-1-4939-7219-7_16 PMID: 28791646

Investigating the role of the transcription factor Hindsight in the regulation of EGFR/Ras/MAPK signaling: new applications for CRISPR/Cas9 genome editing

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Reed, Bruce

Keywords: egfr/ras/mapk signaling; transcriptional regulation; programmed cell death; crispr/cas9 genome editing; genetic screens

$180,000

Investigating the function of Hindsight/RREB-1 in the intestinal stem cell lineage of Drosophila

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Reed, Bruce

$190,000

The genetic analysis of autophagy-dependent caspase activity in drosophila

Principal investigatorNSERC2010Discovery Grants Program - Individual

Principal investigators: Reed, Bruce

$135,000

Fluorescence microscope with deconvolution and extended depth-of-focus imaging capabilities

Principal investigatorNSERC2008Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Reed, Bruce

$126,921

Digital imaging capability for NSERC sponsored, milti-user core microscope facility

Co-investigatorNSERC2007Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Spafford, David

$125,895

Contact dependent inhibition of cell death in Drosophila

Principal investigatorNSERC2005Discovery Grants Program - Individual

Principal investigators: Reed, Bruce

$182,500

High resolution fluorescence stereomicroscope

Principal investigatorNSERC2005Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Reed, Bruce

$48,035

Routing and perfect graphs

Principal investigatorNSERC1991Discovery Grants Program - Individual

Principal investigators: Reed, Bruce

$16,000

Disjoint paths and cycles in graphs; collaborative research at the Universidade Estadual de Campinas, Depto. Ciencia da Computacao, Brazil

Principal investigatorNSERC1990International Collaborative Research Grant

Principal investigators: Reed, Bruce

$1,732

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biology
Molecular Biology and Biochemistry
Biomedical Physiology and Kinesiology

Co-authors at University of Waterloo, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Nicholas Harden

Molecular Biology and Biochemistry

2 shared papers, latest 2021

Charles Krieger

Biomedical Physiology and Kinesiology

1 shared papers, latest 2021

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2020

Subject: Prospective PhD student: CRISPR/Cas9 genome editing Dear Professor Reed, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "20-hydroxyecdysone (20E) signaling regulates amnioserosa morphogenesis during Drosophila dorsal closure: EcR modulates gene expression in a complex with the AP-1 subunit, Jun." (2021), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Investigating the role of the transcription factor Hindsight in the regulation of EGFR/Ras/MAPK signaling: new applications for CRISPR/Cas9 genome editing" (2020), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]