Fred Possmayer, Western University

Research

Read how they describe their research on their Western University profile.

Latest papers

Reflections on the introduction of surfactant therapy for neonates with respiratory distress.
American journal of physiology. Lung cellular and molecular physiology · 2025 · first author
Pulmonary Surfactant: A Mighty Thin Film.
Chemical reviews · 2023 · first author
The COVID-19 pandemic: a target for surfactant therapy?
Expert review of respiratory medicine · 2021 · senior author

All 29 publications

Latest funding

Liquid metal gold/bismuth ion source for an existing ToF-SSIMS: detection and imaging of complex surfac molecules
NSERC · 2005 · Co-investigator
$133,943
Biophysical studies of functional and dysfunctional pulmonary surfactants
NSERC · 2003 · Co-investigator
$56,073
A micro-trough for studies of pulmonary surfactants
NSERC · 2000 · Co-investigator
$22,483

All 6 grants and awards

29 publications.

01

Reflections on the introduction of surfactant therapy for neonates with respiratory distress.

Possmayer F, Veldhuizen RAW, Jobe AH

American journal of physiology. Lung cellular and molecular physiology2025First author

DOI: 10.1152/ajplung.00355.2024 PMID: 39951688

02

Pulmonary Surfactant: A Mighty Thin Film.

Possmayer F, Zuo YY, Veldhuizen RAW, Petersen NO

Chemical reviews2023First author

DOI: 10.1021/acs.chemrev.3c00146 PMID: 37862151

03

The COVID-19 pandemic: a target for surfactant therapy?

Veldhuizen RAW, Zuo YY, Petersen NO, Lewis JF, Possmayer F

Expert review of respiratory medicine2021Senior author

DOI: 10.1080/17476348.2021.1865809 PMID: 33331197

04

The wet bridge transfer system: a novel tool to assess exogenous surfactant as a vehicle for intrapulmonary drug delivery.

Baer B, Veldhuizen EJA, Possmayer F, Yamashita C, Veldhuizen R

Discovery medicine2018

PMID: 30695680

05

The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders.

Thomas RH, Meeking MM, Mepham JR, Tichenoff L, Possmayer F, Liu S, MacFabe DF

Journal of neuroinflammation2012

DOI: 10.1186/1742-2094-9-153 PMID: 22747852

06

A modified squeeze-out mechanism for generating high surface pressures with pulmonary surfactant.

Keating E, Zuo YY, Tadayyon SM, Petersen NO, Possmayer F, Veldhuizen RA

Biochimica et biophysica acta2012

DOI: 10.1016/j.bbamem.2011.12.007 PMID: 22206628

07

Retinoic acid is a key regulatory switch determining the difference between lung and thyroid fates in Xenopus laevis.

Wang JH, Deimling SJ, D'Alessandro NE, Zhao L, Possmayer F, Drysdale TA

BMC developmental biology2011

DOI: 10.1186/1471-213x-11-75 PMID: 22185339

08

Atomic force microscopy analysis of rat pulmonary surfactant films.

Jiao X, Keating E, Tadayyon S, Possmayer F, Zuo YY, Veldhuizen RA

Biophysical chemistry2011

DOI: 10.1016/j.bpc.2011.06.001 PMID: 21704443

09

A ToF-SIMS study of the lateral organization of lipids and proteins in pulmonary surfactant systems.

Keating E, Waring AJ, Walther FJ, Possmayer F, Veldhuizen RA, Petersen NO

Biochimica et biophysica acta2011

DOI: 10.1016/j.bbamem.2010.11.015 PMID: 21110942

10

Recent advances in alveolar biology: some new looks at the alveolar interface.

Possmayer F, Hall SB, Haller T, Petersen NO, Zuo YY, Bernardino de la Serna J, Postle AD, Veldhuizen RA, Orgeig S

Respiratory physiology & neurobiology2010First author

DOI: 10.1016/j.resp.2010.02.014 PMID: 20206718

Liquid metal gold/bismuth ion source for an existing ToF-SSIMS: detection and imaging of complex surfac molecules

Co-investigatorNSERC2005Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: McIntyre, Stewart

$133,943

Biophysical studies of functional and dysfunctional pulmonary surfactants

Co-investigatorNSERC2003Collaborative Health Research Projects

Principal investigators: Petersen, Nils

$56,073

A micro-trough for studies of pulmonary surfactants

Co-investigatorNSERC2000Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Petersen, NilsOvergaard

$22,483

Structural and Biophysical Basis for (Dys) functional Pulmonary Surfactants

Co-investigatorNSERC1999Collaborative Health Research Projects

Principal investigators: Petersen, Nils

$477,000

Production of human surfactant proteins for artificial surfactant

Principal investigatorNSERC1992Strategic Projects - Group

Principal investigators: Possmayer, Fred

$67,812

Production of human surfactant-associated protein SP-B and SP-C for artficial surfactant

Principal investigatorNSERC1989Strategic Projects - Group

Principal investigators: Possmayer, Fred

$69,820

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Physiology and Pharmacology
Department of Biochemistry
Biochemistry
Dentistry

Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Gilles Lajoie

Biochemistry

1 shared papers, latest 2007

Peter Chidiac

Physiology and Pharmacology

1 shared papers, latest 2009

Moshmi Bhattacharya

Physiology and Pharmacology

1 shared papers, latest 2009

Keith Da Silva

Dentistry

1 shared papers, latest 2005

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Subject: Prospective PhD student Dear Professor Possmayer, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Reflections on the introduction of surfactant therapy for neonates with respiratory distress." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]