This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Western University directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
HR3/RORα-mediated cholesterol sensing regulates TOR signaling.
Nature communications · 2026
Syngeneic adipose-derived stromal cells modulate the immune response but have limited persistence within decellularized adipose tissue implants in C57BL/6 mice.
Acta biomaterialia · 2025
Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice.
The Journal of clinical investigation · 2023
Latest funding
- $100,000
Harnessing adipose-derived stromal cells for subcutaneous soft tissue regeneration: targeting regenerative and immunomodulatory functionality
CIHR · 2021 · Co-investigator
- $250,000
Development of new and innovative strategies in biological mass spectrometry and proteomics
NSERC · 2020 · Principal investigator
- $1,373,176
Metabolomics for prediction of cisplatin mediated acute kidney injury: a Canadian multi-centre adult and pediatric study
CIHR · 2019 · Co-investigator
30 publications.
HR3/RORα-mediated cholesterol sensing regulates TOR signaling.
Lassen M, Pardee K, Bradic I, Pedersen LH, Kubrak O, Ahrentløv N, Clancy S, Koyama T, Necakov A, Liu S, Kuksis A, Lajoie G, Edwards A, Teleman AA, Larsen MR, Krause HM, Texada MJ, Rewitz K
Syngeneic adipose-derived stromal cells modulate the immune response but have limited persistence within decellularized adipose tissue implants in C57BL/6 mice.
Walker JT, Cooper TT, Dunmore-Buyze J, Serack FE, Brooks C, Grant A, Drangova M, Lajoie G, Dekaban GA, Flynn LE
Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice.
Gould NL, Scherer GR, Carvalho S, Shurrush K, Kayyal H, Edry E, Elkobi A, David O, Foqara M, Thakar D, Pavesi T, Sharma V, Walker M, Maitland M, Dym O, Albeck S, Peleg Y, Germain N, Babaev I, Sharir H, Lalzar M, Shklyar B, Hazut N, Khamaisy M, Lévesque M, Lajoie G, Avoli M, Amitai G, Lefker B, Subramanyam C, Shilton B, Barr H, Rosenblum K
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma.
Zhou J, Kong YS, Vincent KM, Dieters-Castator D, Bukhari AB, Glubrecht D, Liu RZ, Quilty D, Findlay SD, Huang X, Xu Z, Yang RZ, Zhang L, Tang E, Lajoie G, Eisenstat DD, Gamper AM, Fahlman R, Godbout R, Postovit LM, Fu Y
Comparison of CX-4945 and SGC-CK2-1 as inhibitors of CSNK2 using quantitative phosphoproteomics: Triple SILAC in combination with inhibitor-resistant CSNK2.
Menyhart D, Gyenis L, Jurcic K, Roffey SE, Puri A, Jovanovic P, Szkop KJ, Pittock P, Lajoie G, Axtman AD, Larsson O, Topisirovic I, Litchfield DW
Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics.
Gyenis L, Menyhart D, Cruise ES, Jurcic K, Roffey SE, Chai DB, Trifoi F, Fess SR, Desormeaux PJ, Núñez de Villavicencio Díaz T, Rabalski AJ, Zukowski SA, Turowec JP, Pittock P, Lajoie G, Litchfield DW
Embryonic protein NODAL regulates the breast tumor microenvironment by reprogramming cancer-derived secretomes.
Dieters-Castator D, Dantonio PM, Piaseczny M, Zhang G, Liu J, Kuljanin M, Sherman S, Jewer M, Quesnel K, Kang EY, Köbel M, Siegers GM, Leask A, Hess D, Lajoie G, Postovit LM
ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to γδ T cell immunotherapy.
Dutta I, Dieters-Castator D, Papatzimas JW, Medina A, Schueler J, Derksen DJ, Lajoie G, Postovit LM, Siegers GM
Characterization of photosynthetic ferredoxin from the Antarctic alga Chlamydomonas sp. UWO241 reveals novel features of cold adaptation.
Cvetkovska M, Szyszka-Mroz B, Possmayer M, Pittock P, Lajoie G, Smith DR, Hüner NPA
Increased Expression of GM1 Detected by Electrospray Mass Spectrometry in Rat Primary Embryonic Cortical Neurons Exposed to Glutamate Toxicity.
Park DH, Wang L, Pittock P, Lajoie G, Whitehead SN
Harnessing adipose-derived stromal cells for subcutaneous soft tissue regeneration: targeting regenerative and immunomodulatory functionality
Principal investigators: Flynn, Lauren E
Keywords: Adipogenesis; Adipose-Derived Stromal Cells; Angiogenesis; Bioscaffolds; Cell Therapy; Dynamic Culture; Immunomodulation; Macrophages; Preconditioning; Subcutaneous Soft Tissue Regeneration
Development of new and innovative strategies in biological mass spectrometry and proteomics
Principal investigators: Lajoie, Gilles
Keywords: proteomics; mass spectrometry; sample preparation; post-translational modifications; bioinformatics; protein-protein interactions; middle down protoemics; antibody characterization; peptides; chemical modifications
Metabolomics for prediction of cisplatin mediated acute kidney injury: a Canadian multi-centre adult and pediatric study
Principal investigators: Urquhart, Bradley L; Blydt-Hansen, Tom; Zappitelli, Michael
Keywords: Acute Kidney Injury; Cisplatin; Drug Toxicity; Metabolomics; Nephrotoxicity
Formation of an islet regenerative niche using human mesenchymal stem cell secreted signals
Principal investigators: Hess, David A
Keywords: Beta Cell Proliferation; Diabetes; Human Islet Culture; Human Mesenchymal Stem Cells; Islet Neogenesis; Islet Regeneration; Quantitative Proteomics; Secretome Analyses; Transplantation; Wnt-Signalling
A nano-UPLC system for the Q-Exactive mass spectrometer
Principal investigators: Lajoie, Gilles
Engineering Adipogenesis for Soft Tissue Regeneration
Principal investigators: Flynn, Lauren E
Keywords: Adipose Tissue Engineering; Adipose-Derived Stem/Stromal Cells; Angiogenesis; Bioreactors; Bioscaffolds; Extracellular Matrix; Inflammation; Microenvironment; Proteomics; Regenerative Medicine
Development of New Approaches and Methods in Biological Mass Spectrometry and Proteomics.
Principal investigators: Lajoie, Gilles
Control of Cell Proliferation & Survival: Pathological Rewiring of Regulatory Pathways by Protein Kinase CK2.
Principal investigators: Litchfield, David W
Keywords: Apoptosis; Cell Survival; Chemical Biology; Protein Kinase; Protein Kinase Inhibitor; Proteomics; Signal Transduction
Multiple peptide synthesizer for biochemical and biophysical studies
Principal investigators: Lajoie, Gilles
Novel methods in mass spectrometry-based proteomics
Principal investigators: Lajoie, Gilles
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Andrew Leask and Lynne-Marie Postovit: 4 shared papers
- Ivan Topisirovic and Lynne-Marie Postovit: 4 shared papers
- Lynne-Marie Postovit and Gilles Lajoie: 3 shared papers
- Mikko Karttunen and Gilles Lajoie: 3 shared papers
- Aled Edwards and Keith Pardee: 2 shared papers
- Lynne-Marie Postovit and David Hess: 2 shared papers
- Roseline Godbout and Lynne-Marie Postovit: 1 shared paper
- Roseline Godbout and Richard Fahlman: 1 shared paper
- Roseline Godbout and Gilles Lajoie: 1 shared paper
- Massimo Avoli and Gilles Lajoie: 1 shared paper
- Massimo Avoli and Vijendra Sharma: 1 shared paper
- Andrew Leask and David Hess: 1 shared paper
- Andrew Leask and Maria Drangova: 1 shared paper
- Andrew Leask and Gilles Lajoie: 1 shared paper
- Aled Edwards and Gilles Lajoie: 1 shared paper
- Aled Edwards and Aleksandar Necakov: 1 shared paper
- Ivan Topisirovic and Gilles Lajoie: 1 shared paper
- Lynne-Marie Postovit and Richard Fahlman: 1 shared paper
- Keith Pardee and Gilles Lajoie: 1 shared paper
- Keith Pardee and Aleksandar Necakov: 1 shared paper
- David Hess and Gilles Lajoie: 1 shared paper
- Maria Drangova and Gilles Lajoie: 1 shared paper
- Richard Fahlman and Gilles Lajoie: 1 shared paper
- Lina Dagnino and Gilles Lajoie: 1 shared paper
- Fred Possmayer and Gilles Lajoie: 1 shared paper
- Gilles Lajoie and Aleksandar Necakov: 1 shared paper
- Gilles Lajoie and Bin Ma: 1 shared paper
- Gilles Lajoie and Vijendra Sharma: 1 shared paper
- Biochemistry
- Oncology
- Physiology and Pharmacology
- Chemistry
- Terrence Donnelly Centre for Cellular and Biomolecular Research
- Biological Sciences Department
- Dentistry
- Other
Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Lynne-Marie Postovit
Oncology
3 shared papers, latest 2023
Mikko Karttunen
Chemistry
3 shared papers, latest 2011
Vijendra Sharma
Department of Biomedical Sciences
1 shared papers, latest 2023
Aleksandar Necakov
Biological Sciences Department
1 shared papers, latest 2026
Bin Ma
Computer Science
1 shared papers, latest 2009
Andrew Leask
Dentistry
1 shared papers, latest 2021
Aled Edwards
Terrence Donnelly Centre for Cellular and Biomolecular Research
1 shared papers, latest 2026
Ivan Topisirovic
Lady Davis Institute for Medical Research
1 shared papers, latest 2023
Roseline Godbout
Oncology
1 shared papers, latest 2023
David Hess
Physiology and Pharmacology
1 shared papers, latest 2021
Maria Drangova
Medical Biophysics
1 shared papers, latest 2025
Richard Fahlman
Biochemistry
1 shared papers, latest 2023
Lina Dagnino
Physiology and Pharmacology
1 shared papers, latest 2009
Fred Possmayer
Department of Biochemistry
1 shared papers, latest 2007
Keith Pardee
Biomolecular Sciences
1 shared papers, latest 2026
Massimo Avoli
Neurology and Neurosurgery
1 shared papers, latest 2023
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