Faculty profile

Gediminas Cepinskas

Professor/LHRI Scientist & Director- Centre for Critical Illness ResearchDepartment of Medical BiophysicsWestern University

Gediminas Cepinskas

Professor/LHRI Scientist & Director- Centre for Critical Illness Research

Department of Medical Biophysics

Schulich School of Medicine & Dentistry

Western University

London, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
26 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 1 research grant (1 NSERC), most recently in 2017.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

507

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their Western University profile.

Latest papers

Pathway-level proteomics identifies subcellular trafficking dysregulation as a molecular signature in severe traumatic brain injury.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
Pathway-level profiling of the sepsis proteome reveals immune and transcriptional dysregulation.
Molecular medicine (Cambridge, Mass.) · 2026
Multi-dimensional plasma proteomic profiling elucidates molecular mechanisms and pathophysiological networks in pediatric severe traumatic brain injury.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026

All 71 publications

Latest funding

Effect of intra-dialyzer chilling on microvascular perfusion and the biocompatibility profile of hemodialysis.
SSHRC · 2024 · Co-investigator
$124,866
Strategic Engagement of Patients in Sepsis preclinical Studies (SEPSIS): A Priority-Setting Exercise to Identify Patient Important Questions
CIHR · 2023 · Co-investigator
$25,000
Sex differences in preclinical models of sepsis: a systematic review
CIHR · 2020 · Co-investigator
$112,500

All 8 grants and awards

71 publications.

Pathway-level proteomics identifies subcellular trafficking dysregulation as a molecular signature in severe traumatic brain injury.

Van Nynatten LR, Tweddell D, Daley M, Cepinskas G, Basmaji J, Slessarev M, Fraser DD

Inflammation research : official journal of the European Histamine Research Society ... [et al.]2026

DOI: 10.1007/s00011-026-02287-6 PMID: 42373949

Pathway-level profiling of the sepsis proteome reveals immune and transcriptional dysregulation.

Van Nynatten LR, Tweddell D, Daley M, Cepinskas G, Basmaji J, Slessarev M, Fraser DD

Molecular medicine (Cambridge, Mass.)2026

DOI: 10.1186/s10020-026-01469-6 PMID: 41928087

Multi-dimensional plasma proteomic profiling elucidates molecular mechanisms and pathophysiological networks in pediatric severe traumatic brain injury.

Cela E, Tweddell D, Daley M, Morello M, Cepinskas G, Fraser DD

Inflammation research : official journal of the European Histamine Research Society ... [et al.]2026

DOI: 10.1007/s00011-026-02209-6 PMID: 41896418

Proteomic profiling and pathway analyses reveal molecular signatures and immune networks in pediatric sepsis.

Stranges V, Van Nynatten LR, Tweddell D, Cela E, Morello M, Daley M, O'Gorman DB, Cepinskas G, Fraser DD

Inflammation research : official journal of the European Histamine Research Society ... [et al.]2026

DOI: 10.1007/s00011-026-02200-1 PMID: 41896381

Inflammatory-neurodegenerative crosstalk in pediatric severe traumatic brain injury: a multi-domain plasma proteomic study.

Cela E, Van Nynatten LR, Tweddell D, Daley M, Morello M, Cepinskas G, Fraser DD

Molecular medicine (Cambridge, Mass.)2026

DOI: 10.1186/s10020-026-01501-9 PMID: 42135641

Differential expression of plasma proteins and pathway enrichments in pediatric diabetic ketoacidosis.

Spagnolo P, Cela E, Patel MA, Tweddell D, Daley M, Clarson C, Stranges S, Cepinskas G, Fraser DD

Molecular medicine (Cambridge, Mass.)2025

DOI: 10.1186/s10020-024-01056-7 PMID: 39773407

Putative biomarkers of hepatic dysfunction in critically ill sepsis patients.

Van Nynatten LR, Patel MA, Daley M, Miller MR, Cepinskas G, Slessarev M, Russell JA, Fraser DD

Clinical and experimental medicine2025

DOI: 10.1007/s10238-024-01545-3 PMID: 39751971

Assessing the effects of fluids and antibiotics in an acute murine model of sepsis: study protocol for the National Preclinical Sepsis Platform-01 (NPSP-01) Study.

Jahandideh F, Mendelson AA, Liaw PC, Gill SE, Bourque S, Fox-Robichaud AE, Cepinskas G, Macala KF, Sunohara-Neilson J, Engelberts D, Sontag D, Dwivedi DJ, Yu IL, Batnyam O, Mbuta K, Fergusson DA, Taljaard M, McDonald B, Lalu MM

F1000Research2025

DOI: 10.12688/f1000research.163800.3 PMID: 41939488

Differential protein expression and enriched pathways in pediatric sepsis: identification of novel brain-associated biomarkers revealed through proteomic profiling.

Stranges V, Tweddell D, Cela E, Morello M, Daley M, Cepinskas G, Fraser DD

Molecular medicine (Cambridge, Mass.)2025

DOI: 10.1186/s10020-025-01397-x PMID: 41299255

Metabolomic alterations in human brain microvascular endothelial cells induced by traumatic injury.

Cela E, Tweddell D, Patterson EK, Daley M, Cepinskas G, Fraser DD

Metabolomics : Official journal of the Metabolomic Society2025

DOI: 10.1007/s11306-025-02286-4 PMID: 40576909

Effect of intra-dialyzer chilling on microvascular perfusion and the biocompatibility profile of hemodialysis.

Co-investigatorSSHRC2024New Frontiers in Research Fund - Exploration

Principal investigators: Janssen, Barry

$124,866

Strategic Engagement of Patients in Sepsis preclinical Studies (SEPSIS): A Priority-Setting Exercise to Identify Patient Important Questions

Co-investigatorCIHR2023Planning and Dissemination Grant - Institute Community Support

Principal investigators: Lalu, Manoj M; Fergusson, Dean A

Keywords: Nominal Group Technique; Patient Engagement; Patient Partners; Patient Priorities; Priority-Setting; Sepsis

$25,000

Sex differences in preclinical models of sepsis: a systematic review

Co-investigatorCIHR2020Project Grant

Principal investigators: Lalu, Manoj M; Fergusson, Dean A; Fiest, Kirsten M; Fox-Robichaud, Alison E; Gill, Sean E; Liaw, Patricia C; Macala, Kimberly; McDonald, Braedon A

Keywords: Biological Sex Differences; Preclinical Research; Sepsis; Sex Bias

$112,500

National Preclinical Sepsis Platform: Developing a framework for accelerating innovation in Canadian sepsis research

Co-investigatorCIHR2019Planning and Dissemination Grant - Institute Community Support

Principal investigators: Lalu, Manoj M; Fox-Robichaud, Alison E; Kubes, Paul; McIntyre, Lauralyn A; Mendelson, Asher A

Keywords: Discovery Science; Preclinical; Preclinical-To-Clinical Translation; Sepsis

$9,995

Canadian Sepsis Research Network: Improving CareBefore, During and After Sepsis

Co-investigatorCIHR2019Team Grant: Sepsis Research Network - LOI

Principal investigators: Fox-Robichaud, Alison E; Caron, Christine; Fowler, Robert A; Hendrick, Kathryn; Henry, Bonnie J; Kissoon, Niranjan; Liaw, Patricia C; Parolini, Ariana; Schachter, Raymond; Ansermino, John M; Barrett, Kali A; Cook, Catherine L; Fiest, Kirsten M; Fontela, Patricia S; Garland, Allan; Gill, Marlyn; Kho, Michelle E; Kubes, Paul; Lalu, Manoj M; Lamontagne, Francois; Martin, Claudio M; McDonald, Braedon A; McIntyre, Lauralyn A; Parker, Melissa J; Parsons Leigh, Jeanna J; Perry, Jeffrey J; Rochwerg, Bram N; Schwartz, Lisa J; Sherifali, Diana T; Smith, Orla M; Wilcox, Mary E; Yipp, Bryan

Keywords: Biomarkers; Diabetes; Health Economics; Health Literacy; Health Services; Immune Endotypes; Knowledge Transfer; Population Health; Precision Medicine; Sepsis

$24,970

Canadian Sepsis Research Network: Improving Care Before, During and After Sepsis.

Co-investigatorCIHR2019Team Grant: Sepsis Research Network

Principal investigators: Fox-Robichaud, Alison E; Caron, Christine; Fowler, Robert A; Hendrick, Kathryn; Kissoon, Niranjan; Liaw, Patricia C; Parolini, Ariana; Schachter, Raymond; Schwartz, Brian; Ansermino, John M; Cook, Catherine L; Fiest, Kirsten M; Fontela, Patricia S; Garland, Allan; Gill, Marlyn; Kho, Michelle E; Kubes, Paul; Lalu, Manoj M; Lamontagne, Francois; Loubani, Osama; Martin, Claudio M; McDonald, Braedon A; McIntyre, Lauralyn A; Parker, Melissa J; Parsons Leigh, Jeanna J; Perry, Jeffrey J; Rochwerg, Bram N; Schwartz, Lisa J; Sherifali, Diana T; Smith, Orla M; Wilcox, Mary E; Yipp, Bryan

Keywords: Biomarkers; Diabetes And Obesity; Endotypes; Health Economics; Health Literacy; Health Services; Knowledge Transfer; Population Health; Precision Medicine; Sepsis

$5,700,000

Mimicking Vascular Endothelial Cell In Vivo Environment in Cell Culture

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Cepinskas, Gediminas

$156,000

Cerebrovascular outcomes in ischemic heart disease patients undergoing cardiac rehabilitation

Co-investigatorCIHR2015Operating Grant

Principal investigators: Shoemaker, Kevin J

Keywords: Age; Cerebral Blood Flow; Cerebrovascular Reactivity; Endothelial Function; Exercise Training; Translational Research

$848,326

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on November 9, 2025 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Gediminas Cepinskas

Research

Latest papers

Latest funding

Pathway-level proteomics identifies subcellular trafficking dysregulation as a molecular signature in severe traumatic brain injury.

Pathway-level profiling of the sepsis proteome reveals immune and transcriptional dysregulation.

Multi-dimensional plasma proteomic profiling elucidates molecular mechanisms and pathophysiological networks in pediatric severe traumatic brain injury.

Proteomic profiling and pathway analyses reveal molecular signatures and immune networks in pediatric sepsis.

Inflammatory-neurodegenerative crosstalk in pediatric severe traumatic brain injury: a multi-domain plasma proteomic study.

Differential expression of plasma proteins and pathway enrichments in pediatric diabetic ketoacidosis.

Putative biomarkers of hepatic dysfunction in critically ill sepsis patients.

Assessing the effects of fluids and antibiotics in an acute murine model of sepsis: study protocol for the National Preclinical Sepsis Platform-01 (NPSP-01) Study.

Differential protein expression and enriched pathways in pediatric sepsis: identification of novel brain-associated biomarkers revealed through proteomic profiling.

Metabolomic alterations in human brain microvascular endothelial cells induced by traumatic injury.

Effect of intra-dialyzer chilling on microvascular perfusion and the biocompatibility profile of hemodialysis.

Strategic Engagement of Patients in Sepsis preclinical Studies (SEPSIS): A Priority-Setting Exercise to Identify Patient Important Questions

Sex differences in preclinical models of sepsis: a systematic review

National Preclinical Sepsis Platform: Developing a framework for accelerating innovation in Canadian sepsis research

Canadian Sepsis Research Network: Improving CareBefore, During and After Sepsis

Canadian Sepsis Research Network: Improving Care Before, During and After Sepsis.

Mimicking Vascular Endothelial Cell In Vivo Environment in Cell Culture

Cerebrovascular outcomes in ischemic heart disease patients undergoing cardiac rehabilitation

Frequent collaborators

Marat Slessarev

Aurelia Bihari

Claudio Martin

Abdel-Rahman Lawendy

Alfredo Capretta

Braedon McDonald

Alison Fox-Robichaud

Patricia Chia-Ying Liaw

David Sanders

Bertha Garcia

Alp Sener

Martin Sandig

Saverio Stranges

Aaron Haig

Claudia Dos Santos

Stephane Bourque

Haibo Zhang

Justin Presseau

Emil Schemitsch

Donald Welsh

Kirsten Fiest

Patrick Luke

Guillaume Pare

Ian Ball

Karen Li-mei Choong