Karen Bosma, Western University

Research

Read how they describe their research on their Western University profile.

Patient-Ventilator Interaction Proportional Assist Ventilation Randomized Controlled Trial Respiratory Muscle Patient-Ventilator Synchrony/ Dyssynchrony Recovery From Critical Illness Weaning From Mechanical Ventilation Mechanical Ventilation

Latest papers

Cuff leak test and airway obstruction in mechanically ventilated ICU patients (COSMIC): a pilot feasibility randomized controlled trial protocol
BMJ Open · 2025
When donor T cells attack: The curious case of liver transplant-associated acute graft-versus-host-disease.
Science progress · 2022
Improving gender equity in critical care medicine: a protocol to establish priorities and strategies for implementation
BMJ Open · 2020

All 4 publications

Latest funding

Novel Pulmonary Imaging of Lung structure and function in Symptomatic and asymptomatic e-cigarette smokers
CIHR · 2020 · Co-investigator
$100,000
Establishing Stakeholder Priorities for the Development and Implementation of Strategies to Support Gender Equity in Critical Care Medicine
CIHR · 2019 · Co-investigator
$9,970
RECOVER Program: A Care Continuum after Critical Illness
CIHR · 2019 · Co-investigator
$932,280

All 7 grants and awards

4 publications.

01

Cuff leak test and airway obstruction in mechanically ventilated ICU patients (COSMIC): a pilot feasibility randomized controlled trial protocol

Estrada J, Armanious I, Perri D, Cook DJ, Duan EH, Bosma K, Hassall K, Marchildon C, Mehta S, Jaeschke R

BMJ Open20251 citations

DOI: 10.1136/bmjopen-2024-096053

02

When donor T cells attack: The curious case of liver transplant-associated acute graft-versus-host-disease.

Deschner M, Bastin DJ, Solh Z, Bosma K, Haddara W, Yang P, Broadbent R, Haig A, Keow J, Brahmania M, Xenocostas A, Deotare U

Science progress2022

DOI: 10.1177/00368504221117070 PMID: 35979627

03

Improving gender equity in critical care medicine: a protocol to establish priorities and strategies for implementation

Leigh JP, de Grood C, Ahmed S, Bosma K, Burns KEA, Fowler R, Fox-Robichaud A, Mehta S, Mele T, Straus SE

BMJ Open202011 citationsOpen Access

DOI: 10.1136/bmjopen-2020-037090 PMID: W3034648069

04

Comparison of ventilatory modes to facilitate liberation from mechanical ventilation: protocol for a systematic review and network meta-analysis

Lewis KA, Chaudhuri D, Guyatt G, Burns KEA, Bosma K, Ge L, Karachi T, Piraino T, Fernando SM, Ranganath N

BMJ Open201912 citationsOpen Access

DOI: 10.1136/bmjopen-2019-030407 PMID: W2971976793

Novel Pulmonary Imaging of Lung structure and function in Symptomatic and asymptomatic e-cigarette smokers

Co-investigatorCIHR2020Catalyst Grant: Health Effects of Vaping

Principal investigators: Parraga, Grace; Mackenzie, Constance A

Keywords: 129xe Mri; Airways Disease; E-Cigarettes; Emphysema; Lung Failure; Lung Toxicity; Mri; Pulmonary Function; Vaping

$100,000

Establishing Stakeholder Priorities for the Development and Implementation of Strategies to Support Gender Equity in Critical Care Medicine

Co-investigatorCIHR2019Planning and Dissemination Grant - Institute Community Support

Principal investigators: Parsons Leigh, Jeanna J; Paunovic, Bojan; Fiest, Kirsten M; Stelfox, Henry T

Keywords: Collaborative; Critical Care Medicine; Gender Equity; Knowledge Translation; Medical Specialties

$9,970

RECOVER Program: A Care Continuum after Critical Illness

Co-investigatorCIHR2019Team Grant: TiC - Stream 1 - PHSI solutions for transitions in care gaps

Principal investigators: Herridge, Margaret S; Lawless, Bernard; Bayley, Mark T; Flannery, John F; Flockhart, Linda; Misak, Cheryl; Rush, Raphael; Tran, Jake

Keywords: Caregivers Outcomes,; Feasibility And Implementation; Health Care System; Knowledge Translation And Exchange; Patient And Family Engagement; Patient-Centred Outcomes; Post-Icu Care Continuum; Transitions In Care

$932,280

Ultra-Low Tidal Volume Mechanical Ventilation in ARDS Through ECCO2R (ULTIMATE) Pilot Trial

Co-investigatorCIHR2019Project Grant

Principal investigators: Ferguson, Niall D; Fan, Eddy

Keywords: Acute Respiratory Distress Syndrome; Extracorporeal Co2 Removal; Extracorporeal Life Support; Mechanical Ventilation; Ventilator-Induced Lung Injury

$520,200

Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study

Nominated PICIHR2018Project Grant

Principal investigators: Bosma, Karen J; Brochard, Laurent J

Keywords: Patient-Ventilator Interaction; Patient-Ventilator Synchrony/ Dyssynchrony; Proportional Assist Ventilation; Randomized Controlled Trial; Recovery From Critical Illness; Respiratory Muscle; Weaning From Mechanical Ventilation

$501,076

The NEUROlogically-impaired extubation Timing Trial (NEURO-ETT)

Co-investigatorCIHR2015Operating Grant

Principal investigators: Scales, Damon C; Ferguson, Niall D

Keywords: Acute Brain Injury; Extubation; Mechanical Ventilation; Stroke; Tracheostomy

$880,404

Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation

Nominated PICIHR2014Operating Grant: Industry-partnered Collaborative Research

Principal investigators: Bosma, Karen J

Keywords: Mechanical Ventilation; Patient-Ventilator Interaction; Patient-Ventilator Synchrony; Proportional Assist Ventilation; Randomized Controlled Trial; Respiratory Muscle

$140,952

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Health Research Methods, Evidence, and Impact
Critical Care Medicine
PATHOLOGY & LABORATORY MEDICINE, Western University
Anesthesia
Pediatrics
Infectious Diseases/Internal Medicine
Other

1 shared papers, latest 2025

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Paper to mention

Subject: Prospective PhD student: Patient-Ventilator Interaction Dear Professor Bosma, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Cuff leak test and airway obstruction in mechanically ventilated ICU patients (COSMIC): a pilot feasibility randomized controlled trial protocol" (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]