Faculty profile

Laurent Brochard

ResearcherCritical Care MedicineUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Laurent Brochard

Researcher

Critical Care Medicine

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
132 publications in the last five years, latest in 2026.
Senior (last) author on 50 recent papers, a sign of leading a research group.
Principal investigator on 7 research grants (7 CIHR), most recently in 2025.
Supervisor on 4 trainee awards (4 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

322

Publications

8,526

Citations

135

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Mechanical Ventilation Acute Respiratory Distress Syndrome Acute Lung Injury Pneumonia Acute Hypoxemic Respiratory Failure Artificial Intelligence Functional Outcomes Patient-Ventilator Interaction

Latest papers

Careful ventilation in acute respiratory distress syndrome: the protocol of the CAVIARDS international multicentre randomised basket trial
BMJ Open · 2026 · senior author
Magnitude and pattern of breathing effort during spontaneous breathing trials after cardiac surgery: a physiological model of sustained breathing effort despite diaphragm dysfunction
Critical Care · 2026 · senior author
High-flow nasal cannula versus noninvasive ventilation in stabilized hypercapnic exacerbation: a physiological crossover trial
Annals of Intensive Care · 2026 · senior author

All 322 publications

Latest funding

Clinical Implications of Potentially Injurious Patient-Ventilator Interaction Phenotypes. A longitudinal cohort study embedded within a platform of clinical trials testing different ventilation strategies.
CIHR · 2025 · Principal investigator
$661,726
Effects of Spontaneous Breathing, Positive Airway Pressure, and Protective Mechanical Ventilation in a Preclinical Swine Model of Acute Lung Injury. The SPARC Study
CIHR · 2025 · Supervisor
$120,000
Protective Mechanical Ventilation during Acute Lung Injury Targeting Lungs, Circulation, Diaphragm and Brain - Preclinical experiments.
CIHR · 2024 · Nominated PI
$1,055,700

All 32 grants and awards

From the 150 most recent of 322 publications.

Careful ventilation in acute respiratory distress syndrome: the protocol of the CAVIARDS international multicentre randomised basket trial

Coudroy R, Telias I, Jonkman A, Thille AW, Diehl J, Péron N, Ko M, Bourion A-A, Tiribelli N, Fredes S

BMJ Open20261 citationsSenior author

DOI: 10.1136/bmjopen-2025-115775

Magnitude and pattern of breathing effort during spontaneous breathing trials after cardiac surgery: a physiological model of sustained breathing effort despite diaphragm dysfunction

Telias I, Grassi A, Sklar MC, Junhasavasdikul D, Grieco DL, Dres M, Piraino T, Castellvi-Font A, Pham T, Melo L

Critical Care20261 citationsSenior author

DOI: 10.1186/s13054-026-06004-x

High-flow nasal cannula versus noninvasive ventilation in stabilized hypercapnic exacerbation: a physiological crossover trial

Vieira F, Schreiber A, Docci M, Rodrigues A, Phoophiboon V, Subira C, Ko M, Sousa MLA, Pham T, Piraino T

Annals of Intensive Care20261 citationsSenior author

DOI: 10.1016/j.aicoj.2026.100092

Distinct weaning phenotypes in patients unsuccessful in weaning from invasive mechanical ventilation: a secondary analysis of the WEAN SAFE cohort

Caldecott R, Zhu Y, McNicholas BA, Rezoagli E, Taran S, Pham T, Heunks L, Bellani G, Brochard L, Simpkin AJ

Intensive Care Medicine2026

DOI: 10.1007/s00134-026-08592-2

Influence of leaks and mask design on CO2 clearance during non-invasive ventilation: a combined bench and physiological study.

Wongtirawit N, Butterworth R, Vieira F, Schreiber A, Ko M, Brochard L

BMJ open respiratory research2026Senior author

DOI: 10.1136/bmjresp-2026-004135 PMID: 42618283

ARDS management beyond the guidelines: a practical physiology-based approach to individualized care.

Wongtirawit N, Menga LS, Brito R, Docci M, Plens GM, Alcala G, Cantan B, Bosma KJ, Ko M, Roman-Sarita G, Purcell T, Raimondi Cominesi D, Greendyk RA, Brochard L

Intensive care medicine2026Senior author

DOI: 10.1007/s00134-026-08563-7 PMID: 42611192

Publisher Correction: Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome.

Plens GM, Morris IS, Greendyk R, Castellví-Font A, Jonkman AH, Grieco DL, Alcala GC, Dianti J, Amato MBP, Dres M, Bihari S, Khemani RG, Brochard L, Itagaki T, Goligher EC

Intensive care medicine2026

DOI: 10.1007/s00134-026-08557-5 PMID: 42474727

Reply to Monares-Zepeda and Barrera-Hoffmann: Association between mechanical power and ventilator-induced lung injury: a question of size and shape.

Brochard L, Jonson B

American journal of respiratory and critical care medicine2026First author

DOI: 10.1093/ajrccm/aamag365 PMID: 42432855

Extracorporeal CO2 elimination for acute exacerbation of severe COPD requiring invasive mechanical ventilation: a randomized controlled trial (the X-COPD trial).

Karagiannidis C, Riera J, Blanco-Schweizer P, Strassmann S, Merten M, Brodie D, Staudinger T, Windisch W, Brochard L, Slutsky AS

Critical care (London, England)2026

DOI: 10.1186/s13054-026-06300-6 PMID: 42693471

Artificial Intelligence Algorithm to Monitor Inspiratory Muscle Effort and Patient-Ventilator Dyssynchrony During Mechanical Ventilation.

Plens GM, Morais CCA, Gregol T, Colpani PB, Alcala GC, Pacheco É, Xia YHW, Dos Santos AC, Malbouisson LM, Brochard L, Kassis EB, Goligher EC, Carvalho CRR, Amato MBP, Costa ELV

Critical care medicine2026

DOI: 10.1097/ccm.0000000000007145 PMID: 42165647

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Mechanical Ventilation Dear Professor Brochard, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Careful ventilation in acute respiratory distress syndrome: the protocol of the CAVIARDS international multicentre randomised basket trial" (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Clinical Implications of Potentially Injurious Patient-Ventilator Interaction Phenotypes. A longitudinal cohort study embedded within a platform of clinical trials testing different ventilation strategies." (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

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Laurent Brochard

Research

Latest papers

Latest funding

Careful ventilation in acute respiratory distress syndrome: the protocol of the CAVIARDS international multicentre randomised basket trial

Magnitude and pattern of breathing effort during spontaneous breathing trials after cardiac surgery: a physiological model of sustained breathing effort despite diaphragm dysfunction

High-flow nasal cannula versus noninvasive ventilation in stabilized hypercapnic exacerbation: a physiological crossover trial

Distinct weaning phenotypes in patients unsuccessful in weaning from invasive mechanical ventilation: a secondary analysis of the WEAN SAFE cohort

Influence of leaks and mask design on CO2 clearance during non-invasive ventilation: a combined bench and physiological study.

ARDS management beyond the guidelines: a practical physiology-based approach to individualized care.

Publisher Correction: Lung- and diaphragm-protective mechanical ventilation in acute respiratory distress syndrome.

Reply to Monares-Zepeda and Barrera-Hoffmann: Association between mechanical power and ventilator-induced lung injury: a question of size and shape.

Extracorporeal CO2 elimination for acute exacerbation of severe COPD requiring invasive mechanical ventilation: a randomized controlled trial (the X-COPD trial).

Artificial Intelligence Algorithm to Monitor Inspiratory Muscle Effort and Patient-Ventilator Dyssynchrony During Mechanical Ventilation.

Frequent collaborators

Irene Telias

Eddy Fan

Tom Piraino

Karen Burns

Lorenzo Del Sorbo

Ewan Goligher

Sangeeta Mehta

Bram Rochwerg

Martin Post

Deborah Cook

Shaf Keshavjee

Dmitry Rozenberg

Maureen Meade

Marcelo Cypel

Dipayan Chaudhuri

Laveena Munshi

George Tomlinson

John Laffey

Mingyao Liu

Akira Kuriyama

Robert Fowler

Hannah Wunsch

Francois Lamontagne

Rosane Nisenbaum

Jonathan Yeung

François Lellouche

Margaret Herridge

Richard Greendyk

Aizhou Wang

Stephanie Sibley

Kimberley Lewis

Nick Daneman

Niall Ferguson

Tetyana Kendzerska

Marat Slessarev

Najib Ayas

Anna Heath

Alistair Johnson

John Muscedere

Ian Young