Faculty profile

Lauralyn McIntyre

ResearcherClinical EpidemiologyUniversity of Ottawa

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Ottawa directory, so their courses and email address may be missing. Find their university profile.

Lauralyn McIntyre

Researcher

Clinical Epidemiology

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
32 publications in the last five years, latest in 2026.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 16 research grants (16 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

130

Publications

6,465

Citations

179

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Ottawa profile.

Mesenchymal Stromal Cells Randomized Controlled Trial Septic Shock Biological Outcomes Clinical Outcomes Adults Mulit-Organ Dysfunction Phase Ii

Latest papers

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026
Critical Care Medicine · 2026
Executive Summary: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026
Critical Care Medicine · 2026
Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026
Intensive Care Medicine · 2026

All 130 publications

Latest funding

Oral Vancomycin for the Prevention of C. difficile Infection in High-Risk HCT and CAR-T Patients (VAPOR-HCT): A Pilot Randomized Placebo-Controlled Trial
CIHR · 2025 · Principal investigator
$100,000
Establishing An International Core Outcome Set for Subarachnoid Hemorrhage (SAH) - What and How to Measure Outcomes in SAH Research
CIHR · 2024 · Co-investigator
$726,752
Predict Severity for Sepsis
CIHR · 2024 · Co-investigator
$543,150

All 46 grants and awards

130 publications.

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

Prescott HC, Antonelli M, Alhazzani W, Møller MH, Alshamsi F, Azevedo LCP, Belley-Cote E, De Waele J, Derde L, Dionne JC

Critical Care Medicine2026178 citations

DOI: 10.1097/ccm.0000000000007075

Executive Summary: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

Prescott HC, Antonelli M, Alhazzani W, Møller MH, Alshamsi F, Azevedo LCP, Belley-Cote E, De Waele J, Derde L, Dionne JC

Critical Care Medicine2026104 citations

DOI: 10.1097/ccm.0000000000007089

Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026

Prescott HC, Antonelli M, Alhazzani W, Møller MH, Alshamsi F, Azevedo LCP, Belley-Cote E, De Waele J, Derde L, Dionne JC

Intensive Care Medicine202681 citations

DOI: 10.1007/s00134-026-08361-1

Procalcitonin to Guide 7 vs 14 Days of Antibiotics in Bloodstream Infections

Ramendra R, Wright JK, Kain KC, Kim B, Mishra H, Zhong K, Aslanian P, Carignan A, Conly J, Detsky M

JAMA Network Open20262 citations

DOI: 10.1001/jamanetworkopen.2026.20973

Publisher Correction: Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026

Prescott HC, Antonelli M, Alhazzani W, Møller MH, Alshamsi F, Azevedo LCP, Belley-Cote E, De Waele J, Derde L, Dionne JC

Intensive Care Medicine20261 citations

DOI: 10.1007/s00134-026-08410-9

Anti-Xa Levels With Venous Thromboembolism Prophylaxis in Critical Care: A Systematic Review and Meta-Analysis

Durr KM, Ehlebracht A, Rochwerg B, Fernando SM, Gillen JR, Buccholz C, McIntyre L, Carrier M, Siegal DM, Patel R

Critical Care Medicine20261 citations

DOI: 10.1097/ccm.0000000000007079

Pantoprazole Use in Invasively Ventilated Patients With Septic Shock: A Protocol and Statistical Analysis Plan

Kuriyama A, Heels‐Ansdell D, Fernando SM, Adhikari NKJ, Lamontagne F, Teja B, Lewis KA, Rochwerg B, Carayannopoulos KL, Vazquez‐Grande G

Acta Anaesthesiologica Scandinavica2026

DOI: 10.1111/aas.70267

The Association Between Socioeconomic Position and Mortality in Patients With Sepsis and Septic Shock-A Systematic Review and Meta-Analysis.

Almoosawy SA, Fernando SM, Rochwerg B, Durr K, McIntyre L, Seely AJE, Patel R, Tran A

Critical care medicine2026

DOI: 10.1097/ccm.0000000000007053 PMID: 41860316

Evaluating Utility-Weighted Modified Rankin Scale as an Outcome for Clinical Trials in Subarachnoid Hemorrhage: A SAHaRA Secondary Analysis.

Sadan O, Yu Z, Ma T, Delaney A, Fergusson DA, Turgeon AF, Lauzier F, Tuttle A, Watpool I, Chassé M, McIntyre L, Samuels OB, English SW

Neurocritical care2026

DOI: 10.1007/s12028-026-02589-x PMID: 42469581

Safety of intravascular administration of umbilical-cord-derived mesenchymal stromal cells: an updated systematic review and meta-analysis.

Hum C, Poliwoda J, Lalu M, Stewart DJ, Mei SHJ, Walley KR, Marshall J, Mendelson AA, Fergusson DA, English S, Winston BW, Granton J, Dos Santos CC, Champagne J, McIntyre L

Stem cells translational medicine2026Senior author

DOI: 10.1093/stcltm/szag029 PMID: 42246109

Oral Vancomycin for the Prevention of C. difficile Infection in High-Risk HCT and CAR-T Patients (VAPOR-HCT): A Pilot Randomized Placebo-Controlled Trial

Principal investigatorCIHR2025Project Grant - Priority Announcement - Cancer Survivorship

Principal investigators: MacFadden, Derek R; Atkins, Harold L; Buchan, Catharine A; Cheng, Matthew P; Climans, Troy; Coburn, Bryan A; Daneman, Nick; Gauthier, Karine; Hay, Annette; Kabbani, Dima; Kekre, Natasha; Kennah, Michael; McIntyre, Lauralyn A; Mertz, Dominik; Monteith, Bethany E; Mortimer, Leanne M; Purssell, Andrew; Taljaard, Monica; Tsang, Corey

Keywords: Antimicrobial Resistance; Biomarker; C.Difficile Infection; Chimeric Antigen Receptor T-Cell Therapy; Feasibility; Hematopoietic Stem Cell Transplantation; Microbiome; Pilot; Prophylaxis; Randomized Trial

$100,000

Establishing An International Core Outcome Set for Subarachnoid Hemorrhage (SAH) - What and How to Measure Outcomes in SAH Research

Co-investigatorCIHR2024Project Grant

Principal investigators: English, Shane W; Andersen, Christopher R; Marti, Maria Luisa; Presseau, Justin; Shea, Beverley J

Keywords: Aneurysmal Subarachnoid Hemorrhage; Multidisciplinary Team Members; Patient And Family Partners; Patient-Centred Outcome Measures; Patient-Oriented Research

$726,752

Predict Severity for Sepsis

Co-investigatorCIHR2024Project Grant

Principal investigators: Dos Santos, Claudia C; Veres, Teodor

Keywords: Biomarker; Device; Inflammation; Rna; Sepsis; Translational Study

$543,150

Platelet Transfusion Domain of the Canadian Critical Care Comparative Effectiveness Platform(e) d'Évaluation Clinique Comparée en soins Critiques - (CEPEC)

Co-investigatorCIHR2024Project Grant

Principal investigators: Lamontagne, Francois; Adhikari, Neill K; Arnold, Donald M; Callum, Jeannie L; Fowler, Robert A; Menon, Kusum; Tsang, Jennifer L

Keywords: Platelet Transfusion; Randomized Controlled Trial; Supportive Care

$1,193,400

Therapeutic Plasma Exchange in Septic Shock (PLEXSIS): A Pilot Study

Co-investigatorCIHR2022Project Grant

Principal investigators: Rimmer, Emily; Zarychanski, Ryan

Keywords: Critical Care; Sepsis; Septic Shock; Therapeutic Apheresis

$307,530

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

Principal investigators: Daneman, Nick; Murthy, Srinivas; Yamamura, Deborah L; Fowler, Robert A; Johnstone, Jennie; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Paterson, David L; Rogers, Benjamin A; Yahav, Dafna

Keywords: Adaptive Platform Trial; Antibiotic De-Escalation; Antibiotic Step-Down; Antimicrobial Resistance; Bloodstream Infection; Central Venous Catheter Infection; Gram Negative Bacteremia; Randomized Controlled Trial

$729,947

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects

$2,919,785

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock: A Phase II RCT

Nominated PICIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

Principal investigators: McIntyre, Lauralyn A; Fox-Robichaud, Alison E; Fergusson, Dean A; Mendelson, Asher A; Stewart, Duncan J; Walley, Keith R

Keywords: Adults; Biological Outcomes; Clinical Outcomes; Mesenchymal Stromal Cells; Mulit-Organ Dysfunction; Phase Ii; Placebo Controlled; Randomized Controlled Trial; Septic Shock; Umbilical Cord

$329,678

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock: A Phase II RCT

Nominated PICIHR2022Operating Grant: Clinical Trials Projects

Principal investigators: McIntyre, Lauralyn A; Fox-Robichaud, Alison E; Fergusson, Dean A; Mendelson, Asher A; Stewart, Duncan J; Walley, Keith R

Keywords: Adults; Biological Outcomes; Clinical Outcomes; Mesenchymal Stromal Cells; Mulit-Organ Dysfunction; Phase Ii; Placebo Controlled; Randomized Controlled Trial; Septic Shock; Umbilical Cord

$1,318,714

The Canadian Critical Care Trials Group

Principal investigatorCIHR2020Operating Grant: Clinical Research Infrastructure Support for COVID-19

Principal investigators: Fowler, Robert A; Burns, Karen E; Choong, Karen; Cook, Deborah J; Gilfoyle, Elaine; Lamontagne, Francois; Marshall, John C; McIntyre, Lauralyn A; Meade, Maureen O; Muscedere, John; Seely, Andrew J; Sinuff, Tasnim; Turgeon, Alexis F

Keywords: Acute Lung Injury; Blood Transfusions; Clinical Trials; Critical Care; Mechanical Ventilation; Patient-Centred; Quality Of Care; Resuscitation; Sepsis; Traumatic Brain Injury

$150,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Lauralyn McIntyre

Research

Latest papers

Latest funding

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

Executive Summary: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026

Procalcitonin to Guide 7 vs 14 Days of Antibiotics in Bloodstream Infections

Publisher Correction: Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026

Anti-Xa Levels With Venous Thromboembolism Prophylaxis in Critical Care: A Systematic Review and Meta-Analysis

Pantoprazole Use in Invasively Ventilated Patients With Septic Shock: A Protocol and Statistical Analysis Plan

The Association Between Socioeconomic Position and Mortality in Patients With Sepsis and Septic Shock-A Systematic Review and Meta-Analysis.

Evaluating Utility-Weighted Modified Rankin Scale as an Outcome for Clinical Trials in Subarachnoid Hemorrhage: A SAHaRA Secondary Analysis.

Safety of intravascular administration of umbilical-cord-derived mesenchymal stromal cells: an updated systematic review and meta-analysis.

Frequent collaborators

Dean Fergusson

Deborah Cook

Kusum Menon

John Marshall

John Muscedere

Sangeeta Mehta

Ryan Zarychanski

Alan Tinmouth

Diane Heels-Ansdell

Anand Kumar

Peter Dodek

Alison Fox-Robichaud

Emilie Belley-Cote

Shane English

Francois Lamontagne

Nick Daneman

Brian Hutton

Carl van Walraven

François Lauzier

Joanna Dionne

Simon Oczkowski

Monica Taljaard

Maureen Meade

Ruxandra Pinto

Swapnil Hiremath

Erick Duan

Timothy A Karachi

Alan Forster

Justin Presseau

Donald Griesdale

Kednapa Thavorn

Katharine O'Hearn

Claudio Martin

Pavel Geier

Karen Li-mei Choong

Bram Rochwerg

Kimia Honarmand

Murray Krahn

Jennifer Tsang

Marisa Tucci