Faculty profile

Shane English

ResearcherRegenerative MedicineUniversity of Ottawa

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Ottawa directory, so their courses and email address may be missing. Find their university profile.

Shane English

Researcher

Regenerative Medicine

Health Sciences

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
27 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (6 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

969

Citations

h-index

223

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

University Profile Search on Google Scholar

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Signals and details

Research

Read how they describe their research on their University of Ottawa profile.

Aneurysmal Subarachnoid Hemorrhage Patient And Family Partners Patient-Centred Outcome Measures Acute Respiratory Distress Syndrome Adults Biological Outcomes Clinical Outcomes Covid-19

Latest papers

Excitatory amino acid inhibitors in adults with acute moderate to severe traumatic brain injury: a systematic review and meta-analysis.
BMJ open · 2026
Safety of intravascular administration of umbilical-cord-derived mesenchymal stromal cells: an updated systematic review and meta-analysis.
Stem cells translational medicine · 2026
Proton pump inhibitors in invasively ventilated patients with SARS-CoV-2: a substudy of the re-evaluating the inhibition of stress erosions trial
BMJ Open · 2026

All 45 publications

Latest funding

Establishing An International Core Outcome Set for Subarachnoid Hemorrhage (SAH) - What and How to Measure Outcomes in SAH Research
CIHR · 2024 · Nominated PI
$726,752
Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock: A Phase II RCT
CIHR · 2022 · Co-investigator
$329,678
Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock: A Phase II RCT
CIHR · 2022 · Co-investigator
$1,318,714

All 13 grants and awards

45 publications.

Excitatory amino acid inhibitors in adults with acute moderate to severe traumatic brain injury: a systematic review and meta-analysis.

Bouras M, Costerousse O, Verret M, O'connor S, Zarychanski R, Gagnon MA, Torkomyan TH, Ouellet A, Lauzier F, English S, Moore L, Turgeon AF

BMJ open2026

DOI: 10.1136/bmjopen-2025-108337 PMID: 41856577

Safety of intravascular administration of umbilical-cord-derived mesenchymal stromal cells: an updated systematic review and meta-analysis.

Hum C, Poliwoda J, Lalu M, Stewart DJ, Mei SHJ, Walley KR, Marshall J, Mendelson AA, Fergusson DA, English S, Winston BW, Granton J, Dos Santos CC, Champagne J, McIntyre L

Stem cells translational medicine2026

DOI: 10.1093/stcltm/szag029 PMID: 42246109

Proton pump inhibitors in invasively ventilated patients with SARS-CoV-2: a substudy of the re-evaluating the inhibition of stress erosions trial

Dennis B, Heels-Ansdell D, Ibrahim Q, Basmaji J, Thabane L, Guyatt G, Saunders L, Hand L, Loy O, Zytaruk N

BMJ Open2026

DOI: 10.1136/bmjopen-2026-119937

Prognostic Factors Associated with Pneumonia in Patients with Traumatic Brain Injury: A Systematic Review and Meta-analysis

Bitonti TM, Durr KM, Rochwerg B, Fernando S, English S, Meggison H, Kubelik D, Neilipovitz D, Millington S, Turgeon AF

Neurocritical Care2026

DOI: 10.1007/s12028-026-02459-6

Utility of predictive scales for emergency department patients with a new diagnosis of aneurysmal subarachnoid hemorrhage.

Perry JJ, English S

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine2025Senior author

DOI: 10.1111/acem.70010 PMID: 40071544

A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline

McIntyre L, Fergusson D, McArdle T, English S, Cook DJ, Fox-Robichaud AE, Martin C, Marshall J, Pugliese M, Menon K

New England Journal of Medicine202530 citations

DOI: 10.1056/nejmoa2416761

Coenrollment in a critical care trial: Characteristics and consequences

Clarke F, Hand L, Deane A, Zytaruk N, Hardie M, Arabi Y, Al-Fares A, Heels-Ansdell D, Dechert W, Ostermann M

Contemporary Clinical Trials20254 citations

DOI: 10.1016/j.cct.2025.107938

Liberal versus restrictive red blood cell transfusion thresholds in acute acquired brain injury: a systematic review and meta-analysis

Sud S, Guyatt G, Angriman F, Friedrich JO, Scales DC, Turgeon AF, English S, Adhikari NK

BMJ Open20252 citations

DOI: 10.1136/bmjopen-2025-107697

Prophylaxis for venous thromboembolism in traumatic brain injury: protocol for a randomised controlled trial

Pirouzmand F, Mathieu F, Mansouri A, Kavikondala K, Alkins R, Boyd JG, Christie S, Couillard P, Cusimano MD, Engels PT

BMJ Open2025

DOI: 10.1136/bmjopen-2025-114158

Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation

Iqbal M, Reeve B, Forrest D, Trop S, Reynolds S, Saunders L, Heels-Ansdell D, Marshall J, English S, Ostermann M

New England Journal of Medicine2024108 citations

DOI: 10.1056/nejmoa2404245

Establishing An International Core Outcome Set for Subarachnoid Hemorrhage (SAH) - What and How to Measure Outcomes in SAH Research

Nominated PICIHR2024Project Grant

Principal investigators: English, Shane W; Andersen, Christopher R; Marti, Maria Luisa; Presseau, Justin; Shea, Beverley J

Keywords: Aneurysmal Subarachnoid Hemorrhage; Multidisciplinary Team Members; Patient And Family Partners; Patient-Centred Outcome Measures; Patient-Oriented Research

$726,752

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock: A Phase II RCT

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

Principal investigators: McIntyre, Lauralyn A; Fox-Robichaud, Alison E; Fergusson, Dean A; Mendelson, Asher A; Stewart, Duncan J; Walley, Keith R

Keywords: Adults; Biological Outcomes; Clinical Outcomes; Mesenchymal Stromal Cells; Mulit-Organ Dysfunction; Phase Ii; Placebo Controlled; Randomized Controlled Trial; Septic Shock; Umbilical Cord

$329,678

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock: A Phase II RCT

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects

Principal investigators: McIntyre, Lauralyn A; Fox-Robichaud, Alison E; Fergusson, Dean A; Mendelson, Asher A; Stewart, Duncan J; Walley, Keith R

Keywords: Adults; Biological Outcomes; Clinical Outcomes; Mesenchymal Stromal Cells; Mulit-Organ Dysfunction; Phase Ii; Placebo Controlled; Randomized Controlled Trial; Septic Shock; Umbilical Cord

$1,318,714

COVID-19 Variant Supplement - Cellular Immuno-Therapy for COVID-19 Induced Acute Respiratory Distress Syndrome: the CIRCA-19 Trial

Principal investigatorCIHR2021Operating Grant: SARS-CoV-2 variants supplement stream 1

Principal investigators: Stewart, Duncan J; English, Shane W; Fergusson, Dean A

Keywords: Acute Respiratory Distress Syndrome; Adults; Biological Outcomes; Clinical Outcomes; Covid-19; Mechanical Ventilation; Mesenchymal Stromal Cells; Phase Ii; Placebo Controlled; Randomized Controlled Trial

$50,000

Cellular Immuno-Therapy for COVID-19 Induced Acute Respiratory Distress Syndrome: the CIRCA-19 Trial

Principal investigatorCIHR2020Operating Grant: COVID-19 Rapid Research Funding Opportunity - Therapeutics

Principal investigators: Stewart, Duncan J; English, Shane W; Fergusson, Dean A

$1,860,523

Establishing an International Core Outcome Set in SAH - What and When to Measure in SAH Research

Nominated PICIHR2019Project Grant - Priority Announcement: Patient-Oriented Research

Principal investigators: English, Shane W; Marti, Maria Luisa; Presseau, Justin

Keywords: Aneurysmal Subarachnoid Hemorrhage; Multidisciplinary Stakeholders; Patient And Family Partners; Patient-Centred Outcome Measures

$100,000

Crystalloid FLUID Choices for Resuscitation of Hospitalized Patients: A Pragmatic Comparative Effectiveness Trial (FLUID)

Co-investigatorCIHR2018Project Grant

Principal investigators: McIntyre, Lauralyn A; Fergusson, Dean A; Taljaard, Monica

Keywords: Cluster Cross-Over Randomized Controlled Trial; Comparative Effectiveness Trial; Crystalloid Fluid; Fluid Therapy; Normal Saline; Resuscitation; Ringers Lactate

$374,851

Cellular Immunotherapy in Septic Shock: A Meeting to Develop a Stem Cell in Sepsis International Collaborative Network

Co-investigatorCIHR2017Planning and Dissemination Grant - Institute Community Support

Principal investigators: McIntyre, Lauralyn A; Fergusson, Dean A

Keywords: Biological Data; International Meeting; Mesenchymal Stem Cells; Mesenchymal Stromal Cells; Network; Randomized Controlled Trial; Septic Shock

$10,000

An innovative Trial Assessing Donor Sex on Recipient Mortality (iTADS)

Co-investigatorCIHR2016Project Grant

Principal investigators: Fergusson, Dean A; Chasse, Michael; Tinmouth, Alan T

Keywords: Biostatistics; Blood; Blood Utilization; Clinical Trial; Database; Donor; Epidemiology; Transfusion

$371,026

Cellular Immunotherapy for Septic Shock (CISS): A Phase II Trial

Co-investigatorCIHR2016Project Grant

Principal investigators: McIntyre, Lauralyn A; Fergusson, Dean A

Keywords: Biological Outcomes; Clinical Outcomes; Mesenchymal Stem Cells (Mscs); Multi-Centre; Multi-Organ Dysfunction; Phase Ii Trial; Randomized Controlled Trial; Septic Shock

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Shane English

Research

Latest papers

Latest funding

Excitatory amino acid inhibitors in adults with acute moderate to severe traumatic brain injury: a systematic review and meta-analysis.

Safety of intravascular administration of umbilical-cord-derived mesenchymal stromal cells: an updated systematic review and meta-analysis.

Proton pump inhibitors in invasively ventilated patients with SARS-CoV-2: a substudy of the re-evaluating the inhibition of stress erosions trial

Prognostic Factors Associated with Pneumonia in Patients with Traumatic Brain Injury: A Systematic Review and Meta-analysis

Utility of predictive scales for emergency department patients with a new diagnosis of aneurysmal subarachnoid hemorrhage.

A Crossover Trial of Hospital-Wide Lactated Ringer’s Solution versus Normal Saline

Coenrollment in a critical care trial: Characteristics and consequences

Liberal versus restrictive red blood cell transfusion thresholds in acute acquired brain injury: a systematic review and meta-analysis

Prophylaxis for venous thromboembolism in traumatic brain injury: protocol for a randomised controlled trial

Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation

Frequent collaborators

Deborah Cook

John Marshall

John Muscedere

Gordon Guyatt

Lauralyn McIntyre

Diane Heels-Ansdell

Ryan Zarychanski

Bram Rochwerg

Karen Burns

François Lauzier

Ian Ball

Dean Fergusson

Erick Duan

Joanna Dionne

Jennifer Tsang

Kusum Menon

Maureen Meade

Lehana Thabane

Lynne Moore

Donald Griesdale

Alison Fox-Robichaud

Francois Lamontagne

Daniel Niven

Kednapa Thavorn

Sonny Dhanani

Kednapa Thavorn

Feng Xie

Claudio Martin

Matthew Weiss

Shane English

Steven Hawken

Marat Slessarev

Alexandra Binnie

Alexandre Tran

Justin Presseau

Sangeeta Mehta

Kirsten Fiest

Tina Mele

Francois Lamontagne

Ryan Zarychanski