Vania Prado, Western University

Research

Read how they describe their research on their Western University profile.

Acetylcholine Mouse Models Aging Alzheimer'S Disease Cholinergic System Cognition Sex Differences Vacht

Latest papers

Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes.
Acta neuropathologica communications · 2021

All 1 publications

Latest funding

The interplay of cholinergic dysfunction and APOE4 in Alzheimer's disease
CIHR · 2024 · Nominated PI
$1,090,125
Leveraging deep biology for brain resilience to AD pathology
CIHR · 2023 · Co-investigator
$739,560
TRIDENT: TRanslational Initiative to DE-risk NeuroTherapeutics
SSHRC · 2022 · Co-investigator
$8,000,000

All 10 grants and awards

1 publications.

01

Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes.

Xu X, Cowan M, Beraldo F, Schranz A, McCunn P, Geremia N, Brown Z, Patel M, Nygard KL, Khazaee R, Lu L, Liu X, Strong MJ, Dekaban GA, Menon R, Bartha R, Daley M, Mao H, Prado V, Prado MAM, Saksida L, Bussey T, Brown A

Acta neuropathologica communications2021

DOI: 10.1186/s40478-021-01161-2 PMID: 33823944

The interplay of cholinergic dysfunction and APOE4 in Alzheimer's disease

Nominated PICIHR2024Project Grant

Principal investigators: Prado, Vania F

Keywords: Acetylcholine; Aging; Alzheimer'S Disease; Cholinergic System; Cognition; Mouse Models; Sex Differences; Vacht

$1,090,125

Leveraging deep biology for brain resilience to AD pathology

Co-investigatorCIHR2023Operating Grant: Mechanisms in Brain Aging and Dementia

Principal investigators: Schmitz, Taylor W

Keywords: Alzheimer'S Disease; Brain Resilience; Imaging Biomarkers; Mechanisms Of Action; Mouse Models; P75ntr; Pharmacology; Preclinical Trials

$739,560

TRIDENT: TRanslational Initiative to DE-risk NeuroTherapeutics

Co-investigatorSSHRC2022New Frontiers in Research Fund - Transformation

Principal investigators: Menon, Ravi

Keywords: cognition; drug discovery; mouse models; marmoset; organoids; imaging; open science; neurodegenerative disease; neurochemistry; neural circuits; sex differences

$8,000,000

Investigating the role of neuronal STI1 co-chaperone in facilitating in vivo a-synuclein toxicity

SupervisorCIHR2022Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Novikov, Vladislav

Keywords: Biochemistry; Cognitive Testing; Dementia; Immunohistochemistry; Mouse Models Of Disease; Neurodegenerative Disease; Neuroscience; Parkinson'S Disease; Protein Misfolding; Treatment

$105,000

Manipulating astrocyte cholinergic signaling to improve cognition in an Alzheimer's disease mouse model

SupervisorCIHR2021CIHR Fellowship

Principal investigators: Schmidt, Scheila D

Keywords: Alzheimer'S Disease; Astrocytes; Cholinergic Signaling; Cognition; Dreadds Technology; Fiber Photometry Imaging Method; Memory; Neurodegenerative Diseases; Prefrontal Cortex; Touchscreen Tasks

$135,000

Cholinergic influence in aging and brain pathology

Nominated PICIHR2018Project Grant

Principal investigators: Prado, Vania F

Keywords: A-Beta Pathology; Alzheimer'S Disease Mouse Models; Astrocytes; Cellular Senescence; Dreadds; Microglia; Muscarinic Receptors; Neuroinflammation

$956,250

Acetylcholine modulation of circuits important for motivation and goal direct behaviors.

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Prado, Vania

$240,000

Exploring cholinergic mechanisms to understand behavioral deficits in dementia.

Nominated PICIHR2013Operating Grant

Principal investigators: Prado, Vania F

Keywords: Acetylcholine; Attention; Behavior; Behavioral Flexibility; Brain Circuits; Cellular Mechanisms; Dementia; Depression; Mouse Models; Pharmacology

$902,169

Role of acetylcholine in social behaviour

Principal investigatorNSERC2013Discovery Grants Program - Individual

Principal investigators: Prado, Vania

$145,000

Role of acetylcholine in social behaviours

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Prado, Vania

$25,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

John P. Robarts Research Institute
Department of Medical Biophysics
Biochemistry
Other

Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Arthur Brown

John P. Robarts Research Institute

1 shared papers, latest 2021

Robert Bartha

Biochemistry

1 shared papers, latest 2021

Ravi Menon

Department of Medical Biophysics

1 shared papers, latest 2021

Lisa Saksida

Faculty

1 shared papers, latest 2021

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Mention their CIHR grant from 2024

Subject: Prospective PhD student: Acetylcholine Dear Professor Prado, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes." (2021), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "The interplay of cholinergic dysfunction and APOE4 in Alzheimer's disease" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]