Emanuel Rosonina, York University

Research

Gene Expression Rna Polymerase Ii Transcription Yeast Sumoylation Biotinylation Protein Interactions Transcription Factors

Latest papers

Dynamic sumoylation is essential in yeast for suppressing stress-induced gene expression in non-stress conditions.
Nucleic acids research · 2026 · senior author
SUMO protease FUG1, histone reader AL3 and chromodomain protein LHP1 are integral to repeat expansion-induced gene silencing in Arabidopsis thaliana.
Nature plants · 2024
1,10-phenanthroline inhibits sumoylation and reveals that yeast SUMO modifications are highly transient.
EMBO reports · 2024 · senior author

All 12 publications

Latest funding

Examining transcription dynamics with biotin pulse labeling (BPL)
CIHR · 2025 · Nominated PI
$921,825
Mechanisms of transcription reinitiation
NSERC · 2023 · Principal investigator
$70,000
Biomolecular Infrastructure for Detection of Radioisotopes, Fluorescence, Chemiluminescence
NSERC · 2023 · Co-investigator
$139,514

All 8 grants and awards

12 publications.

01

Dynamic sumoylation is essential in yeast for suppressing stress-induced gene expression in non-stress conditions.

Moallem M, McNeil JB, Bergey BG, Rosonina E

Nucleic acids research2026Senior author

DOI: 10.1093/nar/gkag495 PMID: 42165130

02

SUMO protease FUG1, histone reader AL3 and chromodomain protein LHP1 are integral to repeat expansion-induced gene silencing in Arabidopsis thaliana.

Sureshkumar S, Bandaranayake C, Lv J, Dent CI, Bhagat PK, Mukherjee S, Sarwade R, Atri C, York HM, Tamizhselvan P, Shamaya N, Folini G, Bergey BG, Yadav AS, Kumar S, Grummisch OS, Saini P, Yadav RK, Arumugam S, Rosonina E, Sadanandom A, Liu H, Balasubramanian S

Nature plants2024

DOI: 10.1038/s41477-024-01672-5 PMID: 38641663

03

1,10-phenanthroline inhibits sumoylation and reveals that yeast SUMO modifications are highly transient.

McNeil JB, Lee SK, Oliinyk A, Raina S, Garg J, Moallem M, Urquhart-Cox V, Fillingham J, Cheung P, Rosonina E

EMBO reports2024Senior author

DOI: 10.1038/s44319-023-00010-8 PMID: 38182817

04

Sumoylation is Largely Dispensable for Normal Growth but Facilitates Heat Tolerance in Yeast.

Moallem M, Akhter A, Burke GL, Babu J, Bergey BG, McNeil JB, Baig MS, Rosonina E

Molecular and cellular biology2023Senior author

DOI: 10.1080/10985549.2023.2166320 PMID: 36720466

05

Regulating autophagy: a novel role for SETX (Senataxin).

Richard P, Rosonina E

Neural regeneration research2021Senior author

DOI: 10.4103/1673-5374.308091 PMID: 33642381

06

Dynamic sumoylation of promoter-bound general transcription factors facilitates transcription by RNA polymerase II.

Baig MS, Dou Y, Bergey BG, Bahar R, Burgener JM, Moallem M, McNeil JB, Akhter A, Burke GL, Sri Theivakadadcham VS, Richard P, D'Amours D, Rosonina E

PLoS genetics2021Senior author

DOI: 10.1371/journal.pgen.1009828 PMID: 34587155

07

A conserved role for transcription factor sumoylation in binding-site selection.

Rosonina E

Current genetics2019First author

DOI: 10.1007/s00294-019-00992-w PMID: 31093693

08

Sumoylation of DNA-bound transcription factor Sko1 prevents its association with nontarget promoters.

Sri Theivakadadcham VS, Bergey BG, Rosonina E

PLoS genetics2019Senior author

DOI: 10.1371/journal.pgen.1007991 PMID: 30763307

09

Regulation of transcription factors by sumoylation.

Rosonina E, Akhter A, Dou Y, Babu J, Sri Theivakadadcham VS

Transcription2017First author

DOI: 10.1080/21541264.2017.1311829 PMID: 28379052

10

Chromatin Association of Gcn4 Is Limited by Post-translational Modifications Triggered by its DNA-Binding in Saccharomyces cerevisiae.

Akhter A, Rosonina E

Genetics2016Senior author

DOI: 10.1534/genetics.116.194134 PMID: 27770033

Examining transcription dynamics with biotin pulse labeling (BPL)

Nominated PICIHR2025Project Grant

Principal investigators: Rosonina, Emanuel

Keywords: Biotinylation; Gene Expression; Protein Interactions; Rna Polymerase Ii; Transcription; Transcription Factors; Yeast

$921,825

Mechanisms of transcription reinitiation

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Rosonina, Emanuel

Keywords: Gene expression; Gene regulation; Reinitiation; RNA polymerase II; Transcription; Ubiquitination; Yeast

$70,000

Biomolecular Infrastructure for Detection of Radioisotopes, Fluorescence, Chemiluminescence

Co-investigatorNSERC2023Research Tools and Instruments

Principal investigators: Bayfield, Mark

$139,514

High throughput equipment for generating next generation sequencing libraries

Co-investigatorNSERC2021Research Tools and Instruments

Principal investigators: Zayed, Amro

$102,445

Regulation of transcription by SUMO

Nominated PICIHR2021Project Grant

Principal investigators: Rosonina, Emanuel

Keywords: Gene Expression; Gene Regulation; Rna Polymerase Ii; Sumoylation; Transcription; Transcription Factor; Yeast

$803,250

Tetrad Dissection Microscope for Yeast Genetics Analyses

Principal investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Rosonina, Emanuel

$18,594

Regulation of gene expression by protein sumoylation

Nominated PICIHR2015Operating Grant

Principal investigators: Rosonina, Emanuel

Keywords: Gene Expression; General Transcription Factors; Rna Polymerase Ii; Splicing; Sumoylation; Transcription; Yeast

$514,263

Mechanisms of transcription reinitiation

Principal investigatorNSERC2014Discovery Grants Program - Individual

Principal investigators: Rosonina, Emanuel

$280,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Biology
Banting and Best Department of Medical Research
Cellular and Molecular Medicine

Co-authors at York University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Damien D'Amours

Cellular and Molecular Medicine

1 shared papers, latest 2021

Andrew Emili

Banting and Best Department of Medical Research

1 shared papers, latest 2005

Peter Cheung

Biology

1 shared papers, latest 2024

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Gene Expression Dear Professor Rosonina, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Dynamic sumoylation is essential in yeast for suppressing stress-induced gene expression in non-stress conditions." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Examining transcription dynamics with biotin pulse labeling (BPL)" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]