Lyes Kadem, Concordia University

Research

Braids Topology Cardiovascular Fluid Dynamics Cardiovascular Medical Devices Experimental Fluid Mechanics Flow Topology Graph-based methods Patient-specific in vitro Models Soft actuators

Latest papers

An in vitro Experimental Model for Investigating Aortic Pressure Dynamics Under Blunt Thoracic Impacts.
Journal of biomechanical engineering · 2026 · senior author
Numerical investigation of the flow induced by a transcatheter intra-aortic entrainment pump.
Computer methods in biomechanics and biomedical engineering · 2026 · senior author
The Effect of Aortic Regurgitation on Left Ventricular Flow Dynamics Assessed by 4D-Flow MRI.
Annals of biomedical engineering · 2026 · senior author

All 40 publications

Latest funding

Fabrication and characterization of living pulmonary heart valves using 3D (bio)printing and human induced pluripotent stem cell technologies
NSERC · 2025 · Co-investigator
$126,522
An Autonomous Robot for Quantitative UltraSound (ARQUS) Measurements
NSERC · 2023 · Co-investigator
$195,110
Biomimetic Pulmonary Heart Valve for the Treatment of Pediatric Congenital Heart Valve Disease
NSERC · 2023 · Co-investigator
$90,000

All 16 grants and awards

40 publications.

01

An in vitro Experimental Model for Investigating Aortic Pressure Dynamics Under Blunt Thoracic Impacts.

Maraouch G, Horton CH, Fanaberia J, Malorni E, Mignacca GC, Cohen M, Kadem L

Journal of biomechanical engineering2026Senior author

DOI: 10.1115/1.4072112 PMID: 42257894

02

Numerical investigation of the flow induced by a transcatheter intra-aortic entrainment pump.

Park Y, Aycan O, Kadem L

Computer methods in biomechanics and biomedical engineering2026Senior author

DOI: 10.1080/10255842.2025.2471517 PMID: 40014031

03

The Effect of Aortic Regurgitation on Left Ventricular Flow Dynamics Assessed by 4D-Flow MRI.

Abdallah W, Darwish A, Garcia J, Kadem L

Annals of biomedical engineering2026Senior author

DOI: 10.1007/s10439-026-04187-6 PMID: 42228301

04

End-to-end framework integrating generative AI and deep reinforcement learning for autonomous ultrasound scanning.

Elmekki H, Spilkin A, Zakeri E, Zanuttini AM, Alagha A, Sami H, Bentahar J, Kadem L, Xie WF, Pibarot P, Mizouni R, Otrok H, Mourad A, Muhaidat S

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society2026

DOI: 10.1016/j.compmedimag.2026.102819 PMID: 42748510

05

An In-Vitro simulator for investigating flow disturbances in the left ventricle during controlled external impact.

Sweidy D, Mathyssen A, Teimouri K, Wei W, Saleh W, Kadem L, Evin M

Journal of biomechanics2026

DOI: 10.1016/j.jbiomech.2026.113274 PMID: 41934684

06

Hemodynamic performance and blood damage of the Intra-aortic pumps: A CFD-Based investigation.

Aycan O, Park Y, Kadem L

Medical & biological engineering & computing2026Senior author

DOI: 10.1007/s11517-026-03550-y PMID: 41863715

07

A high-fidelity simulator for evaluation of hemodynamic response during cardiopulmonary resuscitation in hypogravity environments.

Lord Z, Andrade C, Leroux L, Kadem L

NPJ microgravity2026Senior author

DOI: 10.1038/s41526-026-00577-1 PMID: 41741473

08

Experimental Investigation of the Effect of a MitraClip on Left Ventricular Flow Dynamics.

Teimouri K, Darwish A, Saleh W, Ng HD, Kadem L

Annals of biomedical engineering2025Senior author

DOI: 10.1007/s10439-025-03744-9 PMID: 40325266

09

CACTUS: An open dataset and framework for automated Cardiac Assessment and Classification of Ultrasound images using deep transfer learning.

Elmekki H, Alagha A, Sami H, Spilkin A, Zanuttini AM, Zakeri E, Bentahar J, Kadem L, Xie WF, Pibarot P, Mizouni R, Otrok H, Singh S, Mourad A

Computers in biology and medicine2025

DOI: 10.1016/j.compbiomed.2025.110003 PMID: 40107020

10

Design, manufacturing, and multi-modal imaging of stereolithography 3D printed flexible intracranial aneurysm phantoms.

Yalman A, Jafari A, Léger É, Mastroianni MA, Teimouri K, Savoji H, Collins DL, Kadem L, Xiao Y

Medical physics2025

DOI: 10.1002/mp.17518 PMID: 39546636

Fabrication and characterization of living pulmonary heart valves using 3D (bio)printing and human induced pluripotent stem cell technologies

Co-investigatorNSERC2025Research Tools and Instruments

Principal investigators: Savoji, Houman

Keywords: heart valves; 3d bioprinting; bioreactor; bioinks; valve interstitial cells; structure-function study; hydrodynamics; tissue engineering; regenerative medicine; human induced pluripotent stem cells

$126,522

An Autonomous Robot for Quantitative UltraSound (ARQUS) Measurements

Co-investigatorNSERC2023Discovery Horizons

Principal investigators: Xie, Wen-Fang

Keywords: Autonomous Robot; Quantitative UltraSound; Control Theory; Cardiology; Cardiovascular Engineering; Deep Reinforcement Learning; Cardiovascular Imaging; Medical Sciences; Computer Science; Mechanical Design

$195,110

Biomimetic Pulmonary Heart Valve for the Treatment of Pediatric Congenital Heart Valve Disease

Co-investigatorNSERC2023Alliance Grants

Principal investigators: Savoji, Houman H

Keywords: 3d (bio)printing; advanced biofabrication techniques; biomechanics; bioreactor; children; heart valves; hydrodynamics; in vitro evaluation; transcatheter pulmonary valve replac

$90,000

Biomimetic 3D (bio)printed pulmonary heart valves for pediatric patients

Co-investigatorSSHRC2023New Frontiers in Research Fund - Exploration

Principal investigators: Savoji, Houman

$250,000

Innovative Methods and Tools for Advanced Analyses of Cardiovascular Flows

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Kadem, Lyes

Keywords: cardiovascular fluid dynamics; cardiovascular medical devices; experimental fluid mechanics; flow topology; braids topology; graph-based methods; patient-specific in vitro models; soft actuators

$117,000

An innovative minimally invasive modular right ventricular assist device

Principal investigatorNSERC2021Alliance Grants

Principal investigators: KADEM, Lyes L

$183,050

Toward the Next-Generation of Heart Assist Devices

Principal investigatorSSHRC2020New Frontiers in Research Fund - Exploration

Principal investigators: Kadem, Lyes

Keywords: Congestive Heart Failure; Medical Device; Experimental Fluid Mechanics; Computational Fluid Mechanics; Fluid-Structure Interaction; Heart Assist Device; Left Ventricle Assist Device

$250,000

An engineered 3D-printed realistic patient simulator: market assessment

Principal investigatorNSERC2017Idea to Innovation

Principal investigators: Kadem, Lyes

$14,977

Optimal and Sub-Optimal Flow Configurations in the Heart: Application to Implantable Medical Devices

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Kadem, Lyes

$185,000

Optimal and Sub-Optimal Flow Configurations in the Heart: Application to Implantable Medical Devices

Principal investigatorNSERC2017Discovery Grants Program - Accelerator Supplements

Principal investigators: Kadem, Lyes

$120,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Mechanical Engineering
Mechanical Industrial and Aerospace Engineering
Cardiology
Concordia Institute for Information Systems Engineering (CIISE)
Mechanical, Industrial & Aerospace Engineering - Concordia University
Département de génie mécanique
Génie biomédical, Institut de
Other

Co-authors at Concordia University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Philippe Pibarot

Cardiology

4 shared papers, latest 2026

Zahra Keshavarz Motamed

Mechanical Engineering

4 shared papers, latest 2015

Jamal Bentahar

Concordia Institute for Information Systems Engineering (CIISE)

3 shared papers, latest 2026

Wen-Fang Xie

Mechanical, Industrial & Aerospace Engineering - Concordia University

3 shared papers, latest 2026

Giuseppe Di Labbio

Département de génie mécanique

2 shared papers, latest 2024

Yiming Xiao

Computer Science and Software Engineering

1 shared papers, latest 2025

Michel Labrosse

Mechanical Engineering

1 shared papers, latest 2015

Lawrence Leroux

Faculty

1 shared papers, latest 2024

Anne Fournier

Faculty

1 shared papers, latest 2015

Guy Cloutier

Génie biomédical, Institut de

1 shared papers, latest 2014

Houman Savoji

Biomedical Engineering

1 shared papers, latest 2025

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2022

Subject: Prospective PhD student: Braids Topology Dear Professor Kadem, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "An in vitro Experimental Model for Investigating Aortic Pressure Dynamics Under Blunt Thoracic Impacts." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Innovative Methods and Tools for Advanced Analyses of Cardiovascular Flows" (2022), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]