Sylvia Santosa, Concordia University

Research

Acetyl Coa Adipocyte Adipose Tissue Bariatric Surgery Body Composition Immune Cells Obesity Preadipocyte

Latest papers

Integrated metabolomics and metagenomics analysis identifies a unique signature characterizing metabolic syndrome.
The Journal of nutritional biochemistry · 2026
T cells are elevated in abdominal and femoral adipose tissue in females with type 2 diabetes.
Journal of the Endocrine Society · 2026 · senior author
Transwell membrane material affects myogenic differentiation in human primary myoblast-adipocyte co-culture.
Physiological reports · 2026 · senior author

All 39 publications

Latest funding

Enhancing Innovative Cellular Analyses through the Acquisition of a Flow Cytometer
NSERC · 2025 · Principal investigator
$150,000
Optimising Bariatric Surgery Outcomes through Interventions Focused on Mental Health Support
CIHR · 2023 · Co-investigator
$6,000
Tummy vs Thighs: Defining Healthy and Unhealthy Subcutaneous Adipose Tissue Characteristics in Obesity and Type 2 Diabetes and the Effects of Surgically Induced Weight Loss
CIHR · 2021 · Nominated PI
$589,050

All 7 grants and awards

39 publications.

01

Integrated metabolomics and metagenomics analysis identifies a unique signature characterizing metabolic syndrome.

Wannaiampikul S, Lee B, Chen J, Prentice KJ, Ayansola R, Xu A, Santosa S, Pantopoulos K, Sweeney G

The Journal of nutritional biochemistry2026

DOI: 10.1016/j.jnutbio.2026.110327 PMID: 41794383

02

T cells are elevated in abdominal and femoral adipose tissue in females with type 2 diabetes.

Delaney KZ, Nadeem MI, Plissonneau C, Khor N, Delaney J, Morais JA, Tsoukas MA, Pescarus R, Garneau PY, Santosa S

Journal of the Endocrine Society2026Senior author

DOI: 10.1210/jendso/bvag117 PMID: 42255513

03

Transwell membrane material affects myogenic differentiation in human primary myoblast-adipocyte co-culture.

Plissonneau C, Tam BT, Garneau PY, Morais JA, Piekny A, Santosa S

Physiological reports2026Senior author

DOI: 10.14814/phy2.70939 PMID: 42260998

04

Is Adipose Tissue Inflammation the Culprit of Obesity-Associated Comorbidities?

Turner L, Wanasinghe AI, Brunori P, Santosa S

Obesity reviews : an official journal of the International Association for the Study of Obesity2025Senior author

DOI: 10.1111/obr.13956 PMID: 40533358

05

The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss.

Murphy J, Morais JA, Tsoukas MA, Cooke AB, Daskalopoulou SS, Santosa S

Frontiers in immunology2025Senior author

DOI: 10.3389/fimmu.2025.1601847 PMID: 40831565

06

Sex differences in the metabolism of glucose and fatty acids by adipose tissue and skeletal muscle in humans.

Costa DN, Santosa S, Jensen MD

Physiological reviews2025

DOI: 10.1152/physrev.00008.2024 PMID: 39869194

07

Combating childhood overweight and obesity: The role of Olympic Movement and bodily movement.

Tam BT, Wan K, Santosa S, Cai Z

Innovation (Cambridge (Mass.))2025

DOI: 10.1016/j.xinn.2024.100771 PMID: 39991475

08

Regional primary preadipocyte characteristics in humans with obesity and type 2 diabetes mellitus.

Plissonneau C, Santosa S

Heliyon2024Senior author

DOI: 10.1016/j.heliyon.2024.e39710 PMID: 39553621

09

Age of obesity onset affects subcutaneous adipose tissue cellularity differently in the abdominal and femoral region.

Murphy J, Dera A, Morais JA, Tsoukas MA, Khor N, Sazonova T, Almeida LG, Cooke AB, Daskalopoulou SS, Tam BT, Santosa S

Obesity (Silver Spring, Md.)2024Senior author

DOI: 10.1002/oby.24059 PMID: 39045668

10

Improvements in cardiorespiratory fitness, muscle strength and body composition to modest weight loss are similar in those with adult- versus childhood-onset obesity.

Almeida LG, Dera A, Murphy J, Santosa S

Clinical obesity2024Senior author

DOI: 10.1111/cob.12623 PMID: 37794721

Enhancing Innovative Cellular Analyses through the Acquisition of a Flow Cytometer

Principal investigatorNSERC2025Research Tools and Instruments

Principal investigators: Santosa, Sylvia

Keywords: immune cells; adipose tissue; cell biology; cell analysis; multicolor immunophenotyping; cellular mechanisms; immune response; metabolic pathways; cytokine production; endocrine signaling

$150,000

Optimising Bariatric Surgery Outcomes through Interventions Focused on Mental Health Support

Co-investigatorCIHR2023CIHR Café Scientifique Program - Institute of Nutrition, Metabolism and Diabetes

Principal investigators: Ben Porat, Tair; Bacon, Simon L; Côté, Marilou; Lavoie, Kim

Keywords: Bariatric Surgery; Behavioural Change; Mental Health; Obesity; Outcomes; Psychological Well-Being; Social Support

$6,000

Tummy vs Thighs: Defining Healthy and Unhealthy Subcutaneous Adipose Tissue Characteristics in Obesity and Type 2 Diabetes and the Effects of Surgically Induced Weight Loss

Nominated PICIHR2021Project Grant

Principal investigators: Santosa, Sylvia

Keywords: Acetyl Coa; Adipocyte; Adipose Tissue; Bariatric Surgery; Body Composition; Immune Cells; Obesity; Preadipocyte; Type 2 Diabetes; Weight Loss

$589,050

Brain health in females across the adult lifespan: quantitative imaging of the effect of estradiol, arterial stiffness, and inflammation on the brain

Co-investigatorCIHR2021Project Grant - PA: Sex and Gender in Health Research (Bridge funding)

Principal investigators: Gauthier, Claudine

Keywords: Brain Imaging; Cerebral Metabolism; Cerebrovascular Health; Endothelial Health; Estradiol And Menopause; Female Aging; Inflammation; Lifespan; Magnetic Resonance Imaging; Vascular Stiffness

$100,000

Cellular and Metabolic Processes in Regional Adipose Tissue

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Santosa, Sylvia

$200,000

Canada Research Chair - Tier 2

Nominated PICIHR2018Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Santosa, Sylvia

Keywords: Crc

$500,000

Acute and Chronic Effects of Adipose Tissue Growth on Cellular and Metabolic Processes

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Santosa, Sylvia

$232,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Mathematics and Statistics
Psychology
Family Medicine
Biology
Nutrition
Nutrition Sciences
Other

Co-authors at Concordia University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Lisa Kakinami

Mathematics and Statistics

4 shared papers, latest 2023

Paula Brauer

Family Relations and Applied Nutrition

1 shared papers, latest 2022

Marie-Claude Audet

Nutrition Sciences

1 shared papers, latest 2023

Sylvie Belleville

Neurology and Neurosurgery

1 shared papers, latest 2023

Doug Klein

Family Medicine

1 shared papers, latest 2022

Sophie Desroches

Sciences des aliments et nutrition

1 shared papers, latest 2022

Sylvie Belleville

Centre de recherche

1 shared papers, latest 2023

Kaberi Dasgupta

Faculty

1 shared papers, latest 2021

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2025

Subject: Prospective PhD student: Acetyl Coa Dear Professor Santosa, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Integrated metabolomics and metagenomics analysis identifies a unique signature characterizing metabolic syndrome." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Enhancing Innovative Cellular Analyses through the Acquisition of a Flow Cytometer" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Sylvia Santosa

Research

Latest papers

Latest funding

Integrated metabolomics and metagenomics analysis identifies a unique signature characterizing metabolic syndrome.

T cells are elevated in abdominal and femoral adipose tissue in females with type 2 diabetes.

Transwell membrane material affects myogenic differentiation in human primary myoblast-adipocyte co-culture.

Is Adipose Tissue Inflammation the Culprit of Obesity-Associated Comorbidities?

The age of obesity onset affects changes in subcutaneous adipose tissue macrophages and T cells after weight loss.

Sex differences in the metabolism of glucose and fatty acids by adipose tissue and skeletal muscle in humans.

Combating childhood overweight and obesity: The role of Olympic Movement and bodily movement.

Regional primary preadipocyte characteristics in humans with obesity and type 2 diabetes mellitus.

Age of obesity onset affects subcutaneous adipose tissue cellularity differently in the abdominal and femoral region.

Improvements in cardiorespiratory fitness, muscle strength and body composition to modest weight loss are similar in those with adult- versus childhood-onset obesity.

Enhancing Innovative Cellular Analyses through the Acquisition of a Flow Cytometer

Optimising Bariatric Surgery Outcomes through Interventions Focused on Mental Health Support

Tummy vs Thighs: Defining Healthy and Unhealthy Subcutaneous Adipose Tissue Characteristics in Obesity and Type 2 Diabetes and the Effects of Surgically Induced Weight Loss

Brain health in females across the adult lifespan: quantitative imaging of the effect of estradiol, arterial stiffness, and inflammation on the brain

Cellular and Metabolic Processes in Regional Adipose Tissue

Canada Research Chair - Tier 2

Acute and Chronic Effects of Adipose Tissue Growth on Cellular and Metabolic Processes

Frequent collaborators

Lisa Kakinami

Paula Brauer

Angela Alberga

Jean-Philippe Drouin-Chartier

Tair Ben Porat

Julie Robitaille

Marie-Claude Audet

Carsten Wrosch

Elham Rahme

Sylvie Belleville

Gary Sweeney

Doug Klein

Sophie Desroches

Kaberi Dasgupta

Sylvie Belleville

Patrick Marion

Carsten Wrosch

Kaberi Dasgupta