Faculty profile
Charles Calmettes
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Research
Latest papers
Engineering human RNase 7 with an eosinophil RNase segment reveals determinants of cytotoxic and antimicrobial activity.
The Journal of biological chemistry · 2026
Author Correction: Mechanism of trans-envelope bacterial polysaccharide secretion in Class-3 outer-membrane polysaccharide export (OPX) protein systems.
Nature communications · 2026 · senior author
Host range and zoonotic potential linked to P-like fimbrial (PLF) adhesin specificity in avian pathogenic Escherichia coli.
PLoS pathogens · 2026
Latest funding
- $715,276
Assembly of virulence factors at the cell surface of Pseudomonas aeruginosa
CIHR · 2018 · Nominated PI
10 publications.
Engineering human RNase 7 with an eosinophil RNase segment reveals determinants of cytotoxic and antimicrobial activity.
Tran TTQ, Larda ST, Nieves C, Veyrier FJ, Calmettes C, Doucet N
Author Correction: Mechanism of trans-envelope bacterial polysaccharide secretion in Class-3 outer-membrane polysaccharide export (OPX) protein systems.
Mellouk A, Ngo K, Kezzo AA, Martini C, França TCC, Laplante SR, Islam ST, Calmettes C
Host range and zoonotic potential linked to P-like fimbrial (PLF) adhesin specificity in avian pathogenic Escherichia coli.
Akrami F, Jamali H, Houle S, Ortiz PA, Calmettes C, Dozois CM
Network-based allosteric analysis of galectin-7: Key residues dictate functional communication and stability.
Pham NTH, Paré A, Létourneau M, Fortier M, Chatenet D, St-Pierre Y, Lagüe P, Calmettes C, Doucet N
Mechanism of trans-envelope bacterial polysaccharide secretion in Class-3 outer-membrane polysaccharide export (OPX) protein systems.
Mellouk A, Ngo K, Kezzo AA, Martini C, França TCC, Laplante SR, Islam ST, Calmettes C
Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases.
Tran TTQ, Narayanan C, Loes AN, Click TH, Pham NTH, Létourneau M, Harms MJ, Calmettes C, Agarwal PK, Doucet N
Unraveling the crystal structure of the HpaA adhesin: insights into cell adhesion function and epitope localization of a Helicobacter pylori vaccine candidate.
Martini C, Araba V, Beniani M, Armoa Ortiz P, Simmons M, Chalbi M, Mellouk A, El Bakkouri M, Calmettes C
Bacterial Outer Membrane Polysaccharide Export (OPX) Proteins Occupy Three Structural Classes with Selective β-Barrel Porin Requirements for Polymer Secretion.
Saïdi F, Mahanta U, Panda A, Kezzo AA, Jolivet NY, Bitazar R, John G, Martinez M, Mellouk A, Calmettes C, Chang YW, Sharma G, Islam ST
Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7.
Pham NTH, Létourneau M, Fortier M, Bégin G, Al-Abdul-Wahid MS, Pucci F, Folch B, Rooman M, Chatenet D, St-Pierre Y, Lagüe P, Calmettes C, Doucet N
Insights into Structural and Dynamical Changes Experienced by Human RNase 6 upon Ligand Binding.
Narayanan C, Bernard DN, Létourneau M, Gagnon J, Gagné D, Bafna K, Calmettes C, Couture JF, Agarwal PK, Doucet N
Assembly of virulence factors at the cell surface of Pseudomonas aeruginosa
Principal investigators: Calmettes, Charles
Keywords: Bacteriology; Biochemistry; Outer-Membrane Proteins; Protein Structure; Structural Biology; Structural Microbiology; X-Ray Crystallography
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Yves St-Pierre and David Chatenet: 5 shared papers
- Charles Calmettes and Yves St-Pierre: 2 shared papers
- Charles Calmettes and David Chatenet: 2 shared papers
- INRS-Institut Armand-Frappier (Laval)
- Other
Co-authors at Institut national de la recherche scientifique, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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