Faculty profile
Yves St-Pierre
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Institut national de la recherche scientifique directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Reassessing galectin inhibition: Lessons for context-selective drug design and translational oncology.
Drug discovery today · 2026 · first author
Network-based allosteric analysis of galectin-7: Key residues dictate functional communication and stability.
Protein science : a publication of the Protein Society · 2026
Absolute Affinities from Quantitative Shotgun Glycomics Using Concentration-Independent (COIN) Native Mass Spectrometry.
ACS central science · 2023
Latest funding
- $105,000
Galectin-7 inhibitors: A new generation of antibodies to target both intracellular and extracellular galectin-7 for triple-negative breast cancer treatment
CIHR · 2023 · Supervisor
- $105,000
Generation of galectin-9-specific single-domain antibodies: new inhibitors to improve immunotherapy of cancer.
CIHR · 2022 · Supervisor
- $371,024
GAL-7-specific nanobodies for treatment of triple-negative breast cancer
CIHR · 2018 · Nominated PI
15 publications.
Reassessing galectin inhibition: Lessons for context-selective drug design and translational oncology.
St-Pierre Y
Network-based allosteric analysis of galectin-7: Key residues dictate functional communication and stability.
Pham NTH, Paré A, Létourneau M, Fortier M, Chatenet D, St-Pierre Y, Lagüe P, Calmettes C, Doucet N
Absolute Affinities from Quantitative Shotgun Glycomics Using Concentration-Independent (COIN) Native Mass Spectrometry.
Bui DT, Favell J, Kitova EN, Li Z, McCord KA, Schmidt EN, Mozaneh F, Elaish M, El-Hawiet A, St-Pierre Y, Hobman TC, Macauley MS, Mahal LK, Flynn MR, Klassen JS
Placental Galectins in Cancer: Why We Should Pay More Attention.
Fuselier C, Dumoulin A, Paré A, Nehmé R, Ajarrag S, Granger Joly de Boissel P, Chatenet D, Doucet N, St-Pierre Y
Quantifying Biomolecular Interactions Using Slow Mixing Mode (SLOMO) Nanoflow ESI-MS.
Bui DT, Li Z, Kitov PI, Han L, Kitova EN, Fortier M, Fuselier C, Granger Joly de Boissel P, Chatenet D, Doucet N, Tompkins SM, St-Pierre Y, Mahal LK, Klassen JS
Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7.
Pham NTH, Létourneau M, Fortier M, Bégin G, Al-Abdul-Wahid MS, Pucci F, Folch B, Rooman M, Chatenet D, St-Pierre Y, Lagüe P, Calmettes C, Doucet N
Binding of a Soluble meso-Tetraarylporphyrin to Human Galectin-7 Induces Oligomerization and Modulates Its Pro-Apoptotic Activity.
López de Los Santos Y, Bernard DN, Egesborg P, Létourneau M, Lafortune C, Cuneo MJ, Urvoas A, Chatenet D, Mahy JP, St-Pierre Y, Ricoux R, Doucet N
Bone morphogenetic protein 4 (BMP-4) and epidermal growth factor (EGF) inhibit metalloproteinase-9 (MMP-9) expression in cancer cells.
Laulan NB, St-Pierre Y
Expression of galectin-7 is induced in breast cancer cells by mutant p53.
Campion CG, Labrie M, Lavoie G, St-Pierre Y
PKC isoforms interact with and phosphorylate DNMT1.
Lavoie G, Estève PO, Laulan NB, Pradhan S, St-Pierre Y
Galectin-7 inhibitors: A new generation of antibodies to target both intracellular and extracellular galectin-7 for triple-negative breast cancer treatment
Principal investigators: Nehmé, Rita
Keywords: Bioinformatics; Galectin-7; Galectins; Immunotherapy; Nanobodies; Proteolysis-Targeting Chimeras (Protacs); Transcriptomics; Triple-Negative Breast Cancer
Generation of galectin-9-specific single-domain antibodies: new inhibitors to improve immunotherapy of cancer.
Principal investigators: Dumoulin, Alyssa
Keywords: Breast Cancer; Galectin Inhibitors; Galectins; Glycomics; Immunotherapy; Single-Domain Antibodies
GAL-7-specific nanobodies for treatment of triple-negative breast cancer
Principal investigators: St-Pierre, Yves
Keywords: Galectins
Investigating DNA hypomethylation in the MMP promoter in cancer cells following exposure to inflammatory cytokines
Principal investigators: Couillard, Julie
Étude de la régulation transcriptionnelle de la galectine-7, un gène impliqué dans l'agressivité du cancer.
Principal investigators: Campion, Carole G
Keywords: Cancer; Cible Thérapeutique; Clonage Moléculaire; Galectine-7; Génétique; Métastases; Méthylation; Régulation Transcriptionnelle; Souris Transgéniques; Études Des Polymorphismes
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Centre Armand-Frappier Santé Biotechnologie
- INRS-Institut Armand-Frappier (Laval)
- Other
Co-authors at Institut national de la recherche scientifique, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
David Chatenet
Faculty
5 shared papers, latest 2026
Charles Calmettes
INRS-Institut Armand-Frappier (Laval)
2 shared papers, latest 2026
Marie-Claude Rousseau
Centre Armand-Frappier Santé Biotechnologie
1 shared papers, latest 2008
Marie-Elise Parent
Centre Armand-Frappier Santé Biotechnologie
1 shared papers, latest 2008
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