Faculty profile
Charles Gauthier
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Research
Latest papers
Lewis-X-Containing Triterpenoid Saponins Inhibit DC-SIGN- and L-SIGN-Mediated Transfer of HIV-1 Infection.
Chemistry (Weinheim an der Bergstrasse, Germany) · 2025 · senior author
Immunological and Toxicological Assessment of Triterpenoid Saponins Bearing Lewis-X- and QS-21-Based Trisaccharides.
Chemistry (Weinheim an der Bergstrasse, Germany) · 2025 · senior author
Exploring fluorinated heptose phosphate analogues as inhibitors of HldA and HldE, key enzymes in the biosynthesis of lipopolysaccharide.
Bioorganic chemistry · 2024
Latest funding
- $703,800
Preclinical evaluation of multicomponent glycoconjugate vaccines against melioidosis
CIHR · 2021 · Nominated PI
28 publications.
Lewis-X-Containing Triterpenoid Saponins Inhibit DC-SIGN- and L-SIGN-Mediated Transfer of HIV-1 Infection.
Gamboa Marin OJ, Ng K, Verma N, Flavien Yapi AG, Pantophlet R, Gauthier C
Immunological and Toxicological Assessment of Triterpenoid Saponins Bearing Lewis-X- and QS-21-Based Trisaccharides.
Gamboa Marin OJ, Adda-Bouchard Y, Sylla B, Verma N, Charpentier T, Huber M, Lopez G, Pichette A, Lamarre A, Gauthier C
Exploring fluorinated heptose phosphate analogues as inhibitors of HldA and HldE, key enzymes in the biosynthesis of lipopolysaccharide.
Cao J, Veytia-Bucheli JI, Liang L, Wouters J, Silva-Rosero I, Bussmann J, Gauthier C, De Bolle X, Groleau MC, Déziel E, Vincent SP
Synthesis and pharmacological evaluation of nature-inspired phenacyl glycosides.
Delar E, Tigherghar Y, Girard L, Haddad M, Ramassamy C, Legault J, Gauthier C
Synthesis and cytotoxicity evaluation of d- and l-sugar-containing mono- and bidesmosidic ursane-type saponins.
Sylla B, Jost G, Lavoie S, Legault J, Gauthier C, Pichette A
Thioarylation of 6-Amino-2,3,6-trideoxy-d-manno-oct-2-ulosonic Acid (IminoKdo): Access to 3,6-Disubstituted Picolinates and Mechanistic Insights.
Manmode S, Hussain N, Marin OJG, Kato A, Veytia-Bucheli JI, Vincent SP, Gauthier C
Structural characterization of a nonionic rhamnolipid from Burkholderia lata.
Gauthier C, Lavoie S, Kubicki S, Piochon M, Cloutier M, Dagenais-Roy M, Groleau MC, Pichette A, Thies S, Déziel E
Synthesis of immunostimulatory saponins: A sweet challenge for carbohydrate chemists.
Gamboa Marin OJ, Heis F, Gauthier C
Early developmental toxicity of Atlantic salmon exposed to conventional and unconventional oils.
Bérubé R, Garnier C, Lefebvre-Raine M, Gauthier C, Bergeron N, Triffault-Bouchet G, Langlois VS, Couture P
C7 Epimerization of Benzylidene-Protected β-d-Idopyranosides Brings Structural Insights into Idose Conformational Flexibility.
Cloutier M, Lavoie S, Gauthier C
Preclinical evaluation of multicomponent glycoconjugate vaccines against melioidosis
Principal investigators: Gauthier, Charles
Keywords: Antibacterial Vaccines; Burkholderia Pseudomallei; Capsular Polysaccharides; Carbohydrate Chemistry; Exopolysaccharides; Glycoconjugate Vaccines; Immunogenicity; Lipopolysaccharides; Melioidosis; Protection Studies
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Charles Gauthier and Maude Cloutier: 6 shared papers
- Ralph Pantophlet and Charles Gauthier: 1 shared paper
- Alain Lamarre and Charles Gauthier: 1 shared paper
- Charles Gauthier and Adnane Sellam: 1 shared paper
- Microbiologie et maladies infectieuses
- INRS-Institut Armand-Frappier (Laval)
- Molecular Biology and Biochemistry
- Other
Co-authors at Institut national de la recherche scientifique, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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