Adrien Peyrache, McGill University

Research

Neuronal Dynamics Learning And Memory Sleep Neuronal Circuits Spatial Navigation Brain Dynamics Crc Cognition

Latest papers

Sleep reveals dynamics integrating and segregating movement and stimulus representations in V1.
Nature communications · 2026
Months-long stability of the head-direction system.
Nature · 2026 · senior author
The postsubiculum as a head-direction cortex.
Trends in neurosciences · 2025 · senior author

All 30 publications

Latest funding

Head direction signals are necessary for the formation of a cognitive map in the hippocampus, and for memory replay during sleep
CIHR · 2025 · Supervisor
$120,000
How dysfunction of hippocampal sharp wave-ripples leads to cognitive impairment in a mouse model of Christianson syndrome.
CIHR · 2024 · Nominated PI
$914,175
The subcortical circuits of spatial cognition and memory formation.
CIHR · 2023 · Nominated PI
$868,276

All 12 grants and awards

30 publications.

01

Sleep reveals dynamics integrating and segregating movement and stimulus representations in V1.

de Oliveira EF, Kim S, Qiu TS, Peyrache A, Batista-Brito R, Sjulson L

Nature communications2026

DOI: 10.1038/s41467-026-75347-4 PMID: 42481470

02

Months-long stability of the head-direction system.

Skromne Carrasco S, Viejo G, Peyrache A

Nature2026Senior author

DOI: 10.1038/s41586-025-10096-w PMID: 41673149

03

The postsubiculum as a head-direction cortex.

Duszkiewicz AJ, Fricker D, Burgalossi A, Peyrache A

Trends in neurosciences2025Senior author

DOI: 10.1016/j.tins.2025.09.004 PMID: 41067986

04

Visual objects refine head direction coding.

Siegenthaler D, Denny H, Carrasco SS, Mayer JL, Levenstein D, Peyrache A, Trenholm S, Macé É

Science (New York, N.Y.)2025

DOI: 10.1126/science.adu9828 PMID: 40934318

05

Stereo olfaction underlies stable coding of head direction in blind mice.

Asumbisa K, Peyrache A, Trenholm S

Nature communications2025

DOI: 10.1038/s41467-025-58847-7 PMID: 40229306

06

A pas de deux between the hippocampus and the cortex during sleep.

Peyrache A

Nature reviews. Neuroscience2024First author

DOI: 10.1038/s41583-024-00828-8 PMID: 38839948

07

Hyperpolarization-activated currents drive neuronal activation sequences in sleep.

Mehrotra D, Levenstein D, Duszkiewicz AJ, Carrasco SS, Booker SA, Kwiatkowska A, Peyrache A

Current biology : CB2024Senior author

DOI: 10.1016/j.cub.2024.05.048 PMID: 38901427

08

Local origin of excitatory-inhibitory tuning equivalence in a cortical network.

Duszkiewicz AJ, Orhan P, Skromne Carrasco S, Brown EH, Owczarek E, Vite GR, Wood ER, Peyrache A

Nature neuroscience2024Senior author

DOI: 10.1038/s41593-024-01588-5 PMID: 38491324

09

Editorial for the special issue: 'Local to large-scale networks in the sleeping brain'.

Peyrache A, Talamini L, Albouy G, Adamantidis A

The European journal of neuroscience2024First author

DOI: 10.1111/ejn.16277 PMID: 38343170

10

Pynapple, a toolbox for data analysis in neuroscience.

Viejo G, Levenstein D, Skromne Carrasco S, Mehrotra D, Mahallati S, Vite GR, Denny H, Sjulson L, Battaglia FP, Peyrache A

eLife2023Senior author

DOI: 10.7554/elife.85786 PMID: 37843985

Head direction signals are necessary for the formation of a cognitive map in the hippocampus, and for memory replay during sleep

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Halawa, Adel

Keywords: Alzheimers; Head Direction; Hippocampus; Manifold; Memory; Navigation; Optogenetics; Place Cells; Rats; Replay

$120,000

How dysfunction of hippocampal sharp wave-ripples leads to cognitive impairment in a mouse model of Christianson syndrome.

Nominated PICIHR2024Project Grant

Principal investigators: Peyrache, Adrien

Keywords: Genetic Disease; Learning And Memory; Neuronal Dynamics; Sleep

$914,175

The subcortical circuits of spatial cognition and memory formation.

Nominated PICIHR2023Project Grant

Principal investigators: Peyrache, Adrien

Keywords: Brain Dynamics; Learning And Memory; Neuronal Circuits; Sleep; Spatial Navigation; Thalamocortical Networks

$868,276

The coupling of spindles and high frequency oscillations during sleep: role in memory and in epilepsy.

Nominated PICIHR2021Project Grant

Principal investigators: Peyrache, Adrien

Keywords: Brain Dynamics; Epilepsy; Learning And Memory; Sleep

$937,125

Canada Reseach Chair - Tier 2

Nominated PICIHR2021Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Peyrache, Adrien

Keywords: Crc

$500,000

The role of the retrosplenial cortex in orienting cognitive maps.

Principal investigatorSSHRC2021New Frontiers in Research Fund - Exploration

Principal investigators: Peyrache, Adrien

Keywords: spatial navigation learning and memory sleep brain dynamics neural networks

$250,000

Brain circuits and dynamics for memory consolidation

Principal investigatorNSERC2018Discovery Launch Supplement

Principal investigators: Peyrache, Adrien

$12,500

Scanning histology and immunohistochemistry-prepared tissue for bridging across scales of molecular, cellular, systems and imaging neuroscience

Co-investigatorNSERC2018Research Tools and Instruments

Principal investigators: Shmuel, Amir

$150,000

Selective real-time monitoring of diverse neuronal types in the brain

Nominated PICIHR2018Joint Canada-Israel Health Research Program

Principal investigators: Peyrache, Adrien; Stark, Eran

Keywords: Cognition; Electrophysiology; Neuronal Cell Types; Neuronal Dynamics; Neurophysiology; Spike Sorting

Brain circuits and dynamics for memory consolidation

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Peyrache, Adrien

$315,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Montreal Neurological Institute
Other

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Igor Timofeev

Faculty

1 shared papers, latest 2016

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2024

Subject: Prospective PhD student: Neuronal Dynamics Dear Professor Peyrache, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Sleep reveals dynamics integrating and segregating movement and stimulus representations in V1." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "How dysfunction of hippocampal sharp wave-ripples leads to cognitive impairment in a mouse model of Christianson syndrome." (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Adrien Peyrache

Research

Latest papers

Latest funding

Sleep reveals dynamics integrating and segregating movement and stimulus representations in V1.

Months-long stability of the head-direction system.

The postsubiculum as a head-direction cortex.

Visual objects refine head direction coding.

Stereo olfaction underlies stable coding of head direction in blind mice.

A pas de deux between the hippocampus and the cortex during sleep.

Hyperpolarization-activated currents drive neuronal activation sequences in sleep.

Local origin of excitatory-inhibitory tuning equivalence in a cortical network.

Editorial for the special issue: 'Local to large-scale networks in the sleeping brain'.

Pynapple, a toolbox for data analysis in neuroscience.

Head direction signals are necessary for the formation of a cognitive map in the hippocampus, and for memory replay during sleep

How dysfunction of hippocampal sharp wave-ripples leads to cognitive impairment in a mouse model of Christianson syndrome.

The subcortical circuits of spatial cognition and memory formation.

The coupling of spindles and high frequency oscillations during sleep: role in memory and in epilepsy.

Canada Reseach Chair - Tier 2

The role of the retrosplenial cortex in orienting cognitive maps.

Brain circuits and dynamics for memory consolidation

Scanning histology and immunohistochemistry-prepared tissue for bridging across scales of molecular, cellular, systems and imaging neuroscience

Selective real-time monitoring of diverse neuronal types in the brain

Brain circuits and dynamics for memory consolidation

Frequent collaborators

Stuart Trenholm

Sylvain Baillet

Igor Timofeev