Stuart Trenholm, McGill University

Research

Functional Ultrasound Imaging Visual Neuroscience Crc 2-Photon Calcium Imaging Artificial Intelligence Behavioral Training Chemogenetics Cortex

Latest papers

Efficient and sustained optogenetic control of sensory and cardiac systems.
Nature biomedical engineering · 2026
RetINaBox: A Hands-On Learning Tool for Experimental Neuroscience.
eNeuro · 2026 · senior author
Visual objects refine head direction coding.
Science (New York, N.Y.) · 2025

All 7 publications

Latest funding

Multiscale analysis of visual object recognition in the mouse
CIHR · 2022 · Nominated PI
$998,325
Canada Research Chair - Tier 2
CIHR · 2021 · Nominated PI
$500,000
A closed-loop brain stimulation system for vision restoration following damage to visual cortex
SSHRC · 2019 · Principal investigator
$271,193

All 8 grants and awards

7 publications.

01

Efficient and sustained optogenetic control of sensory and cardiac systems.

Alekseev A, Hunniford V, Zerche M, Jeschke M, El May F, Vavakou A, Siegenthaler D, Hüser MA, Kiehn SM, Garrido-Charles A, Meyer A, Rambousky A, Alvanos T, Witzke I, Rojas-Garcia KD, Draband MD, Cyganek L, Klein E, Ruther P, Huet A, Trenholm S, Macé E, Kusch K, Bruegmann T, Wolf BJ, Mager T, Moser T

Nature biomedical engineering2026

DOI: 10.1038/s41551-025-01461-1 PMID: 40721511

02

RetINaBox: A Hands-On Learning Tool for Experimental Neuroscience.

Bettler B, Arias Armas F, Cianfarano E, Bordonaro V, Liu MQ, Loukine M, Wan M, Villemain A, Richards BA, Trenholm S

eNeuro2026Senior author

DOI: 10.1523/eneuro.0349-25.2025 PMID: 41526157

03

Visual objects refine head direction coding.

Siegenthaler D, Denny H, Carrasco SS, Mayer JL, Levenstein D, Peyrache A, Trenholm S, Macé É

Science (New York, N.Y.)2025

DOI: 10.1126/science.adu9828 PMID: 40934318

04

Stereo olfaction underlies stable coding of head direction in blind mice.

Asumbisa K, Peyrache A, Trenholm S

Nature communications2025Senior author

DOI: 10.1038/s41467-025-58847-7 PMID: 40229306

05

Flexible cue anchoring strategies enable stable head direction coding in both sighted and blind animals.

Asumbisa K, Peyrache A, Trenholm S

Nature communications2022Senior author

DOI: 10.1038/s41467-022-33204-0 PMID: 36123333

06

An Annotated Journey through Modern Visual Neuroscience.

Trenholm S, Krishnaswamy A

The Journal of neuroscience : the official journal of the Society for Neuroscience2020First author

DOI: 10.1523/jneurosci.1061-19.2019 PMID: 31896562

07

Magnetically guided virus stamping for the targeted infection of single cells or groups of cells.

Schubert R, Herzog S, Trenholm S, Roska B, Müller DJ

Nature protocols2019

DOI: 10.1038/s41596-019-0221-z PMID: 31628446

Multiscale analysis of visual object recognition in the mouse

Nominated PICIHR2022Project Grant

Principal investigators: Trenholm, Stuart

Keywords: 2-Photon Calcium Imaging; Artificial Intelligence; Behavioral Training; Chemogenetics; Cortex; Functional Ultrasound Imaging; Mouse; Visual Neuroscience; Visual Object Recognition

$998,325

Canada Research Chair - Tier 2

Nominated PICIHR2021Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Trenholm, Stuart

Keywords: Crc

$500,000

A closed-loop brain stimulation system for vision restoration following damage to visual cortex

Principal investigatorSSHRC2019New Frontiers in Research Fund - Exploration

Principal investigators: Trenholm, Stuart

Keywords: Visual neuroscience; Cortical visual impairment; Optogenetics; Vision restoration; Closed-loop stimulation; Brain circuit rewiring; Electrophysiology; Spike timing dependent plasticity; Scotoma

$271,193

Scanning histology and immunohistochemistry-prepared tissue for bridging across scales of molecular, cellular, systems and imaging neuroscience

Co-investigatorNSERC2018Research Tools and Instruments

Principal investigators: Shmuel, Amir

$150,000

The development of feature selectivity across the visual system

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Trenholm, Stuart

$266,000

The development of feature selectivity across the visual system

Principal investigatorNSERC2018Discovery Launch Supplement

Principal investigators: Trenholm, Stuart

$12,500

Vision loss, brain circuit rewiring, and vision therapy

Nominated PICIHR2018Project Grant

Principal investigators: Trenholm, Stuart

Keywords: Animal Behavior; Circuit Tracing; Disease Models; Electrophysiology; Functional Ultrasound Imaging; In Vivo Calcium Imaging; Optogenetics; Retinal Degeneration; Vision Restoration; Visual Neuroscience

$979,200

Canada Research Chair - Tier 2

Nominated PICIHR2017Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Trenholm, Stuart

Keywords: Crc

$500,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Montreal Neurological Institute
Physiology
Other

Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Adrien Peyrache

Montreal Neurological Institute

3 shared papers, latest 2025

Arjun Krishnaswamy

Physiology

1 shared papers, latest 2020

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2022

Subject: Prospective PhD student: Functional Ultrasound Imaging Dear Professor Trenholm, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Efficient and sustained optogenetic control of sensory and cardiac systems." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Multiscale analysis of visual object recognition in the mouse" (2022), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]